Gene Information

Name : ASU2_11155 (ASU2_11155)
Accession : YP_006818597.1
Strain : Actinobacillus suis H91-0380
Genome accession: NC_018690
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase aldA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2438656 - 2440137 bp
Length : 1482 bp
Strand : -
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGAAAAATCTAAATGTTTTTGATAAAACTTATGGCTTATTAATTAATGGTGAATGGACTCAGGGAAGCGGTAAAGATTT
ACTCGCTTCTTACAATCCGGCAAACGGTAATGTACTGGCACACTTTGTTGATGCAACCGATGCGGATGTGGATGCAGCAG
TAACAGCAGCACAAGAAGCGTTTAAAACTTGGCGTAAAACAACTACTGCAGAACGAGCTGCCATTTTAAATAAAATTGCC
GATGTGATTGATGAGCATAGTGAATTATTCGCTTTGCAAGAAACGCTAGATAACGGCAAACCAATTCGAGAAACCAGAGC
AGCGGATATCCCGTTGGCTGCCGATCACTTCCGCTATTTTGCCAGTGCCATTCGTGCCGGCGAAGGCAGCTTAAATCAAA
TCAATCAAGAAGAACTTTCGCTCGTACTGCGTGAGCCAATCGGCGTAGTTGGGCAAATTATTCCGTGGAATTTCCCATTC
TTAATGGCGGCATGGAAAATCGCACCGGCTCTTGCCGCCGGCTGTACCGTGGTCATTCACCCTTCCAGTACTACTTCGTT
AAGCCTATTATCCTTTGCACAAAAAATTAATCATTTACTGCCGAAAGGCGTATTAAACGTGATTACCGGTAAAGGTTCGA
AATCCGGTGAATATATGCTTAAACACAAAGGCTTTAACAAACTGGCATTTACCGGTTCGACTGAAGTGGGACGTCATATT
GCGATTTCTGCCGCAGAATTACTCATTCCGGCAACCTTAGAATTAGGCGGTAAATCGGCTAATATTTTCTTTGACGATAT
GCCGTTCGACAAAGCATTAGAGGGCGCACAAAAAGGGATTTTATTCAATCAAGGACAAGTCTGTTGTGCCGGTTCACGCA
TCTTTGTACAAGAAGGAATTTATGACAAATTTGTGGCAGCATTAGCCGAAGAATTTAAGAAAGTCAAAGTCGGTTTACCG
TGGGAAGATGACACTCAAATGGGTGCACAGGTCAATGCGGGACAACTTAACACCATTTTAAAATATGTGAAAATCGGTGA
AGAAGAAGGCTGCCGTATTATTACCGGCGGTAGAAAAGTGTTAGCGGATAATCTTGCCAGCGGTGAATTTGTTGAACCGA
CTTTAATTGAATCGAAAGATAATAACAGCCGAATTGCTCAAGAAGAAATCTTCGGACCGGTGGCAACCGTGATTAAATTT
AAAACCGAAGAAGATGTTATTCGTATGGCGAACGATTCGGAATACGGCTTAGGCGGCGGTGTTTGGACTAAAGACATTAA
CCGTGCATTACGTGTTGCACAAGCGATCGAAACCGGTCGTGTGTGGGTAAATTGTTATAATATTCTGCCGGCAGGCGCAC
CGTTCGGTGGCTATAAATCTTCCGGTATCGGGCGTGAAACCCACCAAATGATGTTAGACGCTTATACCCAAGTGAAAAAT
ATCTACATCAGCACCCGTGAAGAGCGTGAAGGCATGTACTAA

Protein sequence :
MKNLNVFDKTYGLLINGEWTQGSGKDLLASYNPANGNVLAHFVDATDADVDAAVTAAQEAFKTWRKTTTAERAAILNKIA
DVIDEHSELFALQETLDNGKPIRETRAADIPLAADHFRYFASAIRAGEGSLNQINQEELSLVLREPIGVVGQIIPWNFPF
LMAAWKIAPALAAGCTVVIHPSSTTSLSLLSFAQKINHLLPKGVLNVITGKGSKSGEYMLKHKGFNKLAFTGSTEVGRHI
AISAAELLIPATLELGGKSANIFFDDMPFDKALEGAQKGILFNQGQVCCAGSRIFVQEGIYDKFVAALAEEFKKVKVGLP
WEDDTQMGAQVNAGQLNTILKYVKIGEEEGCRIITGGRKVLADNLASGEFVEPTLIESKDNNSRIAQEEIFGPVATVIKF
KTEEDVIRMANDSEYGLGGGVWTKDINRALRVAQAIETGRVWVNCYNILPAGAPFGGYKSSGIGRETHQMMLDAYTQVKN
IYISTREEREGMY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-99 52
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-103 49
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-103 49
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-103 49
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-102 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ASU2_11155 YP_006818597.1 aldehyde dehydrogenase aldA VFG0082 Protein 4e-100 52