Gene Information

Name : ASU2_10720 (ASU2_10720)
Accession : YP_006818511.1
Strain : Actinobacillus suis H91-0380
Genome accession: NC_018690
Putative virulence/resistance : Virulence
Product : RTX-I toxin secretion component
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2341893 - 2343329 bp
Length : 1437 bp
Strand : -
Note : COG0845 Membrane-fusion protein

DNA sequence :
ATGAAAACATGGTTTATGGGATTATGGGAATTTCTCCAACGTTATAAAACCGTTTGGTCAGAAGTTTGGAAAATTCGTCA
TCAACTAGACACTCCAGACCGAGAAAGTGATGAGAGTGAGTTTTTACCGGCACACTTAGAGCTAATTGAAACACCGGTTT
CAAAAAAGCCAAGATTGGTTGCTTACTTAATTATGCTTTTCTTGTTTTTAGCATTGGTCATTTCAATTGTTAGTCACGTG
GAAATTGTTGCTAGCGCTTCAGGAAAACTTACCTTTAGCGGACGCAGTAAAGAAATTAAACCAATTGAAAATGCACTGGT
GAAGGAAATTTTTGTACAAGATGGACAATTTGTACAAAAAGGGGAATTGTTGCTACACCTTACTGCGCTTGGTGCAGATG
CGGATCAACAAAAAACCCAAAGCTCGTTGTCATTGGCAAAATTAGAACGTTATCGTTACGAAACGCTATTAACTGCCGTT
GAAACGAATCATTTGCCATTAATCGAATTAACACATAATGACTTTAGTCACGCCTCTGAAGAGGATAAGACACGGATTCG
TCATTTAATTGTTGAACAATTCGAAGCGTGGCAAAAACAAAAATATCAAAAGGAATTGGTATTACAACGCCGAGAAGCTG
AGAAACAAACGGTTTTAGCTAATATTCGTAAATATGAAGGGATAAGCCGAGTAGAACAGGAAAAATTGAAGGATCTTAAA
AAACTGTTCAATTCAAGATCGGCATCAAAGCACGATGTATTAGCACAAGAAAACCATTATATTGAAGCCGTCAATGAACT
TGCGGTCTATCAATCTCGCTTAAATGAGGTAGAAAGTGACTTACGCCAAGCAAAAGAAGATGCACAATTAATTACGCAAC
TCTTTAAAGCGGATGTACTTGAAAAGCTTAAGCAAAATGTTGAAACGGAAAAGCAACTTAAACTTGAGCTAGAAAAAAAT
GAGCAACGCCAAGTCGCATCAGTCATTCGAGCACCGGTTTCCGGTACGGTACAACAGTTAAAAACCCATACGGTTGGCGG
TGTTGTAACGACCGCAGAAACATTAATGGTGATTGCGCCGGAAGATGATGTTCTTGAAGTCACCGCTTTAATTCAGAATA
AGGACATTGGTTTTATTGAAGTGGGACAAGATGCCGTGATCAAAGTTGAGACATTTCCTTATACTCGCTATGGTTATTTA
ACGGGTAAAGTAAAACATATCACTTTAGAAGCAATTGAGCATCCGCAACTTGGTTTGGTATTTAATACCATTATCTCAAT
TGATAAGAAAACGCTGTCTAGTAAAGATGGCAAAGAGATCGCACTTGGCTCAGGGATGAGCGTTACTGCCGAGATCAAGA
CAGGAGAACGTAGTGTGATTAGTTACTTATTAAGTCCGCTGGAAGAATCTATTTCTGAAAGCTTGAGAGAGCGCTAG

Protein sequence :
MKTWFMGLWEFLQRYKTVWSEVWKIRHQLDTPDRESDESEFLPAHLELIETPVSKKPRLVAYLIMLFLFLALVISIVSHV
EIVASASGKLTFSGRSKEIKPIENALVKEIFVQDGQFVQKGELLLHLTALGADADQQKTQSSLSLAKLERYRYETLLTAV
ETNHLPLIELTHNDFSHASEEDKTRIRHLIVEQFEAWQKQKYQKELVLQRREAEKQTVLANIRKYEGISRVEQEKLKDLK
KLFNSRSASKHDVLAQENHYIEAVNELAVYQSRLNEVESDLRQAKEDAQLITQLFKADVLEKLKQNVETEKQLKLELEKN
EQRQVASVIRAPVSGTVQQLKTHTVGGVVTTAETLMVIAPEDDVLEVTALIQNKDIGFIEVGQDAVIKVETFPYTRYGYL
TGKVKHITLEAIEHPQLGLVFNTIISIDKKTLSSKDGKEIALGSGMSVTAEIKTGERSVISYLLSPLEESISESLRER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 3e-138 64
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 3e-138 64
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 1e-138 64
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 8e-123 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ASU2_10720 YP_006818511.1 RTX-I toxin secretion component VFG0908 Protein 1e-138 64
ASU2_10720 YP_006818511.1 RTX-I toxin secretion component VFG1502 Protein 2e-138 64
ASU2_10720 YP_006818511.1 RTX-I toxin secretion component VFG1556 Protein 8e-139 64
ASU2_10720 YP_006818511.1 RTX-I toxin secretion component VFG0843 Protein 3e-103 50