Gene Information

Name : ureC (ASU2_09490)
Accession : YP_006818267.1
Strain : Actinobacillus suis H91-0380
Genome accession: NC_018690
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 2085959 - 2087677 bp
Length : 1719 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGGCATTAACAATCCCACGCAGTCAGTATGTAGCGACTTACGGCCCGACAGTCGGTGATAAAGTCCGTTTAGGCGACAC
CGATTTATGGGCGACAATTGAACAAGATTTGTTAACCAAAGGCGATGAGTGTAAATTCGGCGGCGGTAAATCGGTACGTG
ACGGTATGGCACAATCAAGCACCGTAACCCGTGATAACCTGAACGTATTGGATTTTGCCCTCACTAATGTGATGATTATC
GACGCAAAATTAGGCATTATCAAAGCGGATATTGGGATTCGTGACGGTCGTATTGTCGGTATCGGTCAGGCGGGTAATCC
GGATACAATGGATAACGTCACGCCAAATATGATTATCGGCGCAAGCACCGAAGTACATAACGGCGCACATTTAATTGCGA
CCGCCGGCGGTATCGATACCCACATTCACTGGATCTGCCCGCAACAGGCACAACACGCTATCGAAAACGGTATTACTACG
ATGATCGGCGGTGGTTCAGGTCCGGCGGACGGCACACACGCCACCACTTGTACACCGGGTAAATTTAACATTGAAAGAAT
GTTCCAAGCTTGCGAATCCTTACCGGTTAATATCGGCTTTTTCGGCAAAGGTAACTGTTCTACGCTTGAACCGCTTAAAG
AACAAGTGGTTGCTGGTGCGTTAGGCTTAAAAATCCACGAAGACTGGGGTGCAACACCGGCAGTGATTGACGCAGCGTTA
AAAGTAGCGGACGAAATGGATGTGCAAGTAGCGATTCACACCGATACGCTCAACGAAAGTGGTTTCTTAGAAGACACGAT
GAAAGCGATTAACGGACGTGTGATTCACACTTTCCACACCGAAGGTGCCGGCGGCGGTCATGCACCGGATATTATTAAAG
CGGCGATGTACCCGAACGTATTACCGGCTTCAACCAATCCAACCCGCCCATTTACTGTGAATACGATTGACGAGCATTTG
GATATGCTGATGGTTTGCCACCATTTAGATAAACGTGTTCCGGAAGATGTCGCATTTGCCGATAGCCGTATCCGTCCTGA
AACGATTGCCGCAGAAGATATTCTGCACGATATGGGCGTGTTCTCAATTATGAGTTCAGACAGTCAAGCAATGGGACGTG
TTGGCGAAGTAGTGACTCGTACGTGGCAGACTGCGGATAAAATGAAAGAACAGCGTGGAGCATTGGGCGATGAAGGTAAC
GACAACTTCCGTATTAAACGCTATATTGCGAAATATACCATCAACCCGGCAATCGCTCACGGTATCAGCCAACACGTTGG
CTCGCTTGAAGTGGGTAAACTGGCGGATATCGTACTATGGAAACCGCAATTCTTCGGTGTAAAACCGGAATTTGTGATGA
AAAAAGGCTTTATCAGCTTTGCTAAAATGGGTGACCCGAATGCGTCAATTCCGACACCACAACCGGTATTCTACCGCCCA
ATGTTTGGGGCAAATGCGAAAGCGAATACTGAAAGTGCAGTTTATTTCGTTTCCCAAGCGAGTGTAGAAGCGGATATCAA
AACCCAATATGGTATCCAGAAAGATACTTTAGCGGTAAAAGGCTGTCGTGATGTAGGTAAAAAAGACCTCGTTCATAATA
ACGCAACGCCTGAAATTACCGTTGATCCGGAACGCTACGAAGTTCGTGTGGACGGCGAGCATATTACTTGCGAACCTGCG
ACTAAAGTGCCGCTTGCACAGCGTTATTTCTTGTTCTAG

Protein sequence :
MALTIPRSQYVATYGPTVGDKVRLGDTDLWATIEQDLLTKGDECKFGGGKSVRDGMAQSSTVTRDNLNVLDFALTNVMII
DAKLGIIKADIGIRDGRIVGIGQAGNPDTMDNVTPNMIIGASTEVHNGAHLIATAGGIDTHIHWICPQQAQHAIENGITT
MIGGGSGPADGTHATTCTPGKFNIERMFQACESLPVNIGFFGKGNCSTLEPLKEQVVAGALGLKIHEDWGATPAVIDAAL
KVADEMDVQVAIHTDTLNESGFLEDTMKAINGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLPASTNPTRPFTVNTIDEHL
DMLMVCHHLDKRVPEDVAFADSRIRPETIAAEDILHDMGVFSIMSSDSQAMGRVGEVVTRTWQTADKMKEQRGALGDEGN
DNFRIKRYIAKYTINPAIAHGISQHVGSLEVGKLADIVLWKPQFFGVKPEFVMKKGFISFAKMGDPNASIPTPQPVFYRP
MFGANAKANTESAVYFVSQASVEADIKTQYGIQKDTLAVKGCRDVGKKDLVHNNATPEITVDPERYEVRVDGEHITCEPA
TKVPLAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 5e-170 65
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 5e-170 65
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-149 61
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-150 61
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-150 61
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-150 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_006818267.1 urease subunit alpha VFG0270 Protein 3e-161 62