Gene Information

Name : ASU2_05740 (ASU2_05740)
Accession : YP_006817525.1
Strain : Actinobacillus suis H91-0380
Genome accession: NC_018690
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease subunit B
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1268442 - 1271015 bp
Length : 2574 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATTTCGAAAAATTTACTACCAAACTGCAAGAAGCTCTTGCAGAAGCCCAATCTTTAGCCATCGGAAAAGATAATAA
CTATATTGAACCGGCACATTTACTTTATGCGTTAGTCAAACAACAAGACGGTTCTATCGCCCCACTATTTACCGCGCTCA
ATGTGCAACCGCAACGTATTTTGAGTGAATTAGAGACGATTTTAAACCGCTTACCGACCGTATCCGGCGGTACAACCCAA
CCGTCACAACAACTGATTCGCCTGTTAAATCAATCTGATAAATTGGCACAACAATTCGGCGATAGCTTTATTTCATCGGA
ATTATTTGTACTTGCCGCACTGGACGATAACGGCGATTTAGGCAAATTATTAAAACAATTTGGCTTAACTAAAGAGAAAG
TAAACAACGCAATCAGCCAAATTCGAGGAGGAGAAAACGTGAATAATCAAAACGCAGAAGAAACCAGACAAGCCCTTCAA
AAATATACCATTGACCTTACCGAACGAGCCAAAGCTGGCAAGCTAGATCCGGTAATCGGTCGTGATGAAGAAATCCGCCG
TGCGGTACAAGTTTTACAACGCCGCACTAAAAATAACCCTGTATTAATCGGTGAACCTGGGGTCGGTAAAACTGCGATCG
TAGAAGGCTTGGCACAACGTATCGTCAACGGCGAAGTGCCGGAAGGTTTAAAAAATAAACGTGTGCTTTCCCTCGATATG
GGCGCATTAATTGCCGGAGCAAAATATCGTGGTGAATTTGAAGAACGTCTAAAAGCGGTACTTAATGAATTAGCCAAAGA
AGAAGGTCAGGTTATTTTATTTATTGATGAAATTCACACTATGGTTGGTGCGGGTAAAACGGACGGCGCAATGGATGCCG
GTAACTTACTCAAACCGTCTCTTGCTCGTGGTGAATTACATTGCGTTGGGGCAACTACACTAGATGAGTATCGCCAATAT
ATCGAAAAAGATGCGGCACTTGAACGTCGTTTCCAAAAAGTATTAGTGGATGAACCTACTGTAGAAGATACGATTGCAAT
TTTACGTGGCTTGAAAGAACGTTATGAAATTCACCACCATGTACAAATTACCGACCCAGCAATCGTAGCAGCGGCAACCC
TTTCGCACCGTTATATTTCCGACCGTCAATTACCGGATAAAGCGATCGATTTAATTGATGAAGCCGCATCCAGTTTACGT
ATGGAAATCGATTCTAAACCTGAGCCGTTAGATAAACTTGAACGCCGTATTATTCAACTTAAATTGGAACGCCAAGCGTT
ACAAAAAGAGGAAGATGAAGCAAGTCGCCAACGTCTTGCAAAATTAGATGAAGAATTGACCGCTCGTGAGCGTGAATATT
CTGAATTGGAAGAAGTTTGGAAAGCGGAGAAATCAGCATTACTCGGTACGCAACATATCAAAACTGAGTTAGAATATGCC
CGTATTGAAATGGATCAAGCTCGCCGTGAAAGTAACTTCGAAAAAATGTCCGAATTACAATACGGTAAAATTCCGGCATT
AGAAAAACAGTTAGCTGAAGCGGTTAAACGTGAGGAAGAAGGCGGAGAGAATCAACTACTTCGTACCAAAGTAACCGATG
AAGAAATTGCAGAAGTGCTTTCTAAAGCAACCGGTATTCCTGTTTCCAAAATGATGGAAGGCGAGAAAGAAAAACTGTTG
CGTATGGAAGAAGTGTTACACAGCCGTGTCATCGGACAAAACGAAGCGGTTGAAGCCGTTGCAAATGCGATTCGCCGTAG
CCGTGCCGGGTTGTCGGATCCGAATCGTCCGATTGGTTCATTCTTATTCCTTGGCCCGACTGGGGTCGGTAAAACCGAAC
TTTGCAAAACCTTGGCGAATTTCCTCTTCGAGGATCCTGATGCGATGGTACGTATCGATATGTCGGAATTTATGGAAAAA
CATAGCGTTTCTCGTTTAGTCGGCGCACCTCCGGGCTATGTCGGTTACGAAGAAGGCGGCTACTTAACCGAAGCGGTTCG
CCGCCGTCCATATTCGGTCGTACTACTTGATGAAGTGGAAAAAGCTCATCCGGACGTGTTTAATATCTTGCTTCAAGTGT
TGGATGACGGTCGTTTAACCGATGGTCAAGGTCGTACGGTAGATTTCCGCAATACGGTGGTGATTATGACATCAAACTTA
GGTTCGCATTTAATCCAAGAAAACCCAGAATTGGATTACGCCAGCATGAAAGAAGTGGTAATGTCAGTGGTAGGACAACA
TTTCCGCCCTGAATTTATCAACCGTATTGATGAAACTGTGGTGTTCCACCCACTTGGTCAAGAGCATATTCGTGCAATTG
CTCGTATTCAATTACAACGTTTAATCGCTCGCCTTGCGGAACGTGGTTACGAAGTGACAGTCACGGATAATGCGTTGGAT
CATATCGGCAAAGCTGGCTTTGACCCGTTATTCGGCGCAAGACCGCTTAAACGTGCAATTCAGCAAGAACTTGAAAATCC
ACTTGCACAACAGATCTTAAGCGGTAAATTATTACCGAATAGCCCTGTTGTGGTGGACTATCAAAATGATCAATTAAGCA
TTAGCAACAGCTAA

Protein sequence :
MNFEKFTTKLQEALAEAQSLAIGKDNNYIEPAHLLYALVKQQDGSIAPLFTALNVQPQRILSELETILNRLPTVSGGTTQ
PSQQLIRLLNQSDKLAQQFGDSFISSELFVLAALDDNGDLGKLLKQFGLTKEKVNNAISQIRGGENVNNQNAEETRQALQ
KYTIDLTERAKAGKLDPVIGRDEEIRRAVQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLDM
GALIAGAKYRGEFEERLKAVLNELAKEEGQVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQY
IEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASSLR
MEIDSKPEPLDKLERRIIQLKLERQALQKEEDEASRQRLAKLDEELTAREREYSELEEVWKAEKSALLGTQHIKTELEYA
RIEMDQARRESNFEKMSELQYGKIPALEKQLAEAVKREEEGGENQLLRTKVTDEEIAEVLSKATGIPVSKMMEGEKEKLL
RMEEVLHSRVIGQNEAVEAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFEDPDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSHLIQENPELDYASMKEVVMSVVGQHFRPEFINRIDETVVFHPLGQEHIRAIARIQLQRLIARLAERGYEVTVTDNALD
HIGKAGFDPLFGARPLKRAIQQELENPLAQQILSGKLLPNSPVVVDYQNDQLSISNS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 9e-110 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ASU2_05740 YP_006817525.1 ATP-dependent Clp protease subunit B VFG2076 Protein 1e-111 45
ASU2_05740 YP_006817525.1 ATP-dependent Clp protease subunit B VFG2084 Protein 5e-112 42
ASU2_05740 YP_006817525.1 ATP-dependent Clp protease subunit B VFG0079 Protein 7e-136 41