Gene Information

Name : O3I_036460 (O3I_036460)
Accession : YP_006812213.1
Strain : Nocardia brasiliensis HUJEG-1
Genome accession: NC_018681
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 8200390 - 8201535 bp
Length : 1146 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGAGTGAATTCGGGTTCTCTACGCGCGCGGTGCATGCCGGGTTCGATCCTGATCCGCAGACCGGCGCGGTGAACGTGCC
CATCTACGCGAGTTCGACCTTCGCCCAGGACGGGGTGGGCGGCCTGCGTGGCGGTTTCGAATACGCCCGCACCGGAAACC
CGACCCGCTCCGCGCTGGAAGCGAACCTCGCCGCGCTCGAATCCGGCCGGTACGGCCGGGCTTTCGCGTCCGGTATGGCC
GCCACCGACTGTGCCCTGCGCGCCACGCTGCGCCCCGGTGACCACATCGTCATCCCGGACGACGCCTACGGCGGCACCTT
CCGCCTGATCGACAAGGTGTTCAGCCAGTGGGGCATCGAACATTCGCCCGCGCACGTCTTCGACGTGGACGAGATGCGCG
CGGCGATCCGCCCGAACACCAAGCTGGTGTGGGTCGAGACGCCGACCAATCCGCTGCTGAGCATCGGCGACATCCCGGCG
CTGGCCGATGTCGCGCACGCCGCGGGCGCAAAACTCGTGGTGGACAACACCTTCGCCACCCCGTACCTGCAGCAGCCGCT
GCAACTCGGCGCCGATATCGTGACGCACTCGACCACGAAATACCTAGGCGGTCACTCCGATGTCGTCGGCGGCGCGCTGA
TCACCAACGATCCCGAACTCGACGCGGCGTTCGCGTTCCTGCAGAACGGCGCGGGCGCGGTGCCCGGACCGTTCGACGCC
TTCCTCACCATGCGCGGCACCAAGACGCTGGCCGTGCGGATGGACCGGCACTGCGACAACGCCGAGACCCTGGTCGAGTT
CCTCGCCGGGCACCCGGCGATCGCGCAGGTGATCTACCCCGGCCTGCCGGAGCACCCGGGTCACCAGGTGGCGGCCAAGC
AGATGCGCCGGTTCGGCGGCATGATCTCGGTGCGGCTGCACGGCGGCGCCGACGCCGCCCGCGAGTTCTGCGCGCGGACC
AAGGTTTTCACCCTGGCCGAGTCGCTGGGTGGAGTGGAATCGCTGATCGAGCACCCGGCCGCGATGACGCACGCGTCGAC
CGAGGGCTCCGTGCTGGAGGTGCCCGCCGACCTCGTCCGGCTGTCGGTCGGCATCGAGGACGTGGCCGATCTGCTCACCG
ATGTCGAGCAAGCCCTCGCGAGCTGA

Protein sequence :
MSEFGFSTRAVHAGFDPDPQTGAVNVPIYASSTFAQDGVGGLRGGFEYARTGNPTRSALEANLAALESGRYGRAFASGMA
ATDCALRATLRPGDHIVIPDDAYGGTFRLIDKVFSQWGIEHSPAHVFDVDEMRAAIRPNTKLVWVETPTNPLLSIGDIPA
LADVAHAAGAKLVVDNTFATPYLQQPLQLGADIVTHSTTKYLGGHSDVVGGALITNDPELDAAFAFLQNGAGAVPGPFDA
FLTMRGTKTLAVRMDRHCDNAETLVEFLAGHPAIAQVIYPGLPEHPGHQVAAKQMRRFGGMISVRLHGGADAAREFCART
KVFTLAESLGGVESLIEHPAAMTHASTEGSVLEVPADLVRLSVGIEDVADLLTDVEQALAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-73 47
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-72 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-55 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O3I_036460 YP_006812213.1 cystathionine gamma-synthase BAC0207 Protein 1e-68 44