Gene Information

Name : O3I_003495 (O3I_003495)
Accession : YP_006805636.1
Strain : Nocardia brasiliensis HUJEG-1
Genome accession: NC_018681
Putative virulence/resistance : Virulence
Product : hydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 775394 - 777007 bp
Length : 1614 bp
Strand : -
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
GTGACTTCGACATCCACCACGCATCGCGCGGGCTACGTCGGCTTCCCCACCGAAGCCGCCGACGCCTACCGCGCCGCCGG
ATACTGGACCGGACGCCCGCTGGCCGACCTGCTGCGCGACACCGCCCGGCGGCATCCGCACCGGCCCGCGCTGCTCGACG
CCGAACAGACGCGCAGCTACGCGTGGCTCGACGCGGAGGCCGACCGGATGGCGCACGGCCTGCTCGCCCTCGGCATCGCG
CCGGGCGACCGGGTGGTGGTGCAGCTGCCGAACGTGCCGGAGTTCTTGACCGTGCTCTTCGGCGCACTACGCGCGGGCAT
CATTCCGGTGCTGACGCTGCCCGCCCACCGCCGGGCCGAAATCGAGCATCTGGCAGCACTTTCCGAAGCCGTCGCCTACA
TCATCGTGGACCGGCTCGGCGACTTCGACTATCGCGAACTGGCCGACACGGTGCGGGCCGCGGTACCGACACTGCGCCAC
GTGCTGGTGGTCGGCGAGCCCGGCGCCGGAACCGATCTGGCCTCGGTGCCCCGCGCGGGCGAGACGCTGCCGGAGATCGA
TCCGAGCGATATCGCGCTGATGCTGGTCTCCGGCGGCACCACGGGTCTGCCGAAACTCATCGCGCGCACCCACGACGACT
ACGCCTACAACGCCACCGCGAGCGCCGCGATCTGCGAACTCACCGAGGACGACGTCTACTTGGCGACCTTGCCTGCCGCA
CACAACTTTCCGCTCGCCTGCCCGGGCATCCTCGGCACCGTGAGCGTGGGCGGCGCGGTGAGCTTCGTCACCGACCCCAG
CCCGGAGAACGCCTTCGCGGCGATCGAACGACACCGGGTGACCGTCACGGCCGTCGTCCCGCCGCTGGCCCAACTGTGGT
GCGCCGCAACCGAATGGGAGGAAGCCGACCTGAGTTCGCTACGGCTGCTCCAGGTGGGCGGCGCGAAGCTGGCCGAGGTC
AACGCGCGCGAGGTCACCCCCGCGCTCGGCGCCACGCTGCAGCAGGTGTTCGGCATGGCGGAGGGCTTGCTCAACTACAC
CCGGCTCGATGACGACACCGAGCTGCTGTGCACCACACAGGGCCGGGCACTCTCGCCCGACGACGAGATCAGGGTGGTGG
ACGCGGACGGCAACGACGTGCCGCCCGGCGCGGAGGGCGAGCTGCTGACCAAGGGCCCCTACACGATTCGCGGCTATTAC
CGCGCGCCCGAGCACAACGCCCGCGCCTTCACCCCCGACGGCTACTACCGCAGCGGTGATCTGGTGCGCCGACTGCCGAG
CGGTCACCTGATCGTCTCCGGACGAATCAAGGACGTGATCAATCGCGGCGGCGAGAACATCTCCTGCGACGAACTCGAGG
AGCACCTGCTCGCGTACCCGGCCGTGCGGCACGCCGCCGCGGTCGGACTGCCCGATCCCACGCTCGGCGAAAAGGTCTGC
GCCGTCCTCGTCGTCGACGGCGATATGCCGACCCTGGCCGAGATCAAGACGTTCCTCATCGACCGCGGTCTGGCCACCTA
CAAACTGCCCGATGTGCTCCGCCGCGCGGACACGCTGCCCGTCACCGCCGTCGGCAAGATCGACAAGAAGGTGCTGCGCG
GCCTCGAGGGGTGA

Protein sequence : 
MTSTSTTHRAGYVGFPTEAADAYRAAGYWTGRPLADLLRDTARRHPHRPALLDAEQTRSYAWLDAEADRMAHGLLALGIA
PGDRVVVQLPNVPEFLTVLFGALRAGIIPVLTLPAHRRAEIEHLAALSEAVAYIIVDRLGDFDYRELADTVRAAVPTLRH
VLVVGEPGAGTDLASVPRAGETLPEIDPSDIALMLVSGGTTGLPKLIARTHDDYAYNATASAAICELTEDDVYLATLPAA
HNFPLACPGILGTVSVGGAVSFVTDPSPENAFAAIERHRVTVTAVVPPLAQLWCAATEWEEADLSSLRLLQVGGAKLAEV
NAREVTPALGATLQQVFGMAEGLLNYTRLDDDTELLCTTQGRALSPDDEIRVVDADGNDVPPGAEGELLTKGPYTIRGYY
RAPEHNARAFTPDGYYRSGDLVRRLPSGHLIVSGRIKDVINRGGENISCDELEEHLLAYPAVRHAAAVGLPDPTLGEKVC
AVLVVDGDMPTLAEIKTFLIDRGLATYKLPDVLRRADTLPVTAVGKIDKKVLRGLEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-108 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-108 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-110 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-110 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-110 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-110 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-110 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-110 50
ybtE CAA21394.1 - Virulence HPI Protein 2e-110 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O3I_003495 YP_006805636.1 hydroxybenzoate-AMP ligase VFG1817 Protein 8e-137 57
O3I_003495 YP_006805636.1 hydroxybenzoate-AMP ligase VFG0168 Protein 1e-105 50
O3I_003495 YP_006805636.1 hydroxybenzoate-AMP ligase VFG0932 Protein 9e-98 44