Gene Information

Name : lysS (O3I_000295)
Accession : YP_006804996.1
Strain : Nocardia brasiliensis HUJEG-1
Genome accession: NC_018681
Putative virulence/resistance : Unknown
Product : lysyl-tRNA ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 70587 - 73907 bp
Length : 3321 bp
Strand : -
Note : COG2898 Uncharacterized conserved protein

DNA sequence :
GTGACCACCACGCAAGCCCGGCAACACCTGATCGAACCGCCAGCCGACAGACCGACCCCGCCTGTGCCGCATCGCGGGCA
CGGCAGGCTGGCCGAGGTCCCGCATATCGCGGGTCTAGTGCTCGGGGTGTTCGCGGTCGCGTGTTTCCTCTGGAGCCTCT
CACCCACCCTGCGCTACCTCACGCAGGTGCCCCGGCACTACATCGACAACTACTACTTCGACGCGCCGGACACGAACCTG
ATGTGGGCGCTGATCGTCGGCCTGCTCGCCGGGGCGCTGGCCAGCCGGAAGCGGATCGCGTGGTGGTTGCTGCTCGGTTA
CGTGTCGCTGTACGCCCTGGCCGAGGGCCTGGATTTCGCGGACACCGGCGATGTCAACGCGCTGGTCGCGATGATCGTGC
ACCTCGCGGTGATCGGTGTGCTGGTCGCGGCGTGGCGTGAGTTCTACACGAAGGTGCGCCGCGGCGCGGGCTGGAAGGCG
CTCGGCGTGCTCGCCGGCGGCCTGACGGTCGGTTTCCTGCTCGGCTGGGGCCTGGTCGAATTGTTCCCCGGATCGCTGCC
GCAGGGCGCGCAGCGGCCCGGCTGGGCGCTGTACCGGGTGACCGCCGCGGTGCTGGTGGACAACGAACGCTTCGACGGGC
ATCCGCGCCCGTTCGTGAACTTCCTGCTCGGTCTGTTCGGCGCGATCGCACTGCTGGCCGCGGTGATCATCCTGCTGCGC
TCCCAGCGCGCGGCGAACGCGATGACCGGCACCGACGAATCCGCGATCCGCGGCCTGCTGGAACGCTCCGACGTCGAGGA
TTCGCTCGGCTACTTCGCGACCCGCCGGGACAAGGCGGTGGTGTTCGCGCCCAGCGGCAAGGCGGCCCTCACCTATCGGG
TCGAGCTGGGCGTGTGCCTGGCCAGCGGCGACCCGGTCGGCATCCGCGAGGCCTGGCCGCAGGCGATCGACGCCTGGCTG
CGGCTGGCCGACCAATTCGGCTGGGCGCCCGCGGTGATGGGCGCGAGCGAACTCGGCGCCACGGCCTACCAGCGCGCGGG
CCTCTCGGTGATCCGGCTCGGCGACGAAGCCATCCTGGATACCAGGACGTTCTCGCTGGCGGGCCCGGAGATGAAACCGG
TGCGCCAGGCCGCGAATCGATTGCGCAAGCACGGCATCACCGTGCGGATCCGGCGGCACCGCGATATCCCGGCCGAGGAG
TTCCGCGCCGTGATCGCGCGTGCCGACGCCTGGCGCGACACCGAGACCGAGCGCGGTTTCTCGATGGCGCTCGGCCGGCT
CGGCGATCCGCTGGACGCCGACTGCCTCCTGGTCGAAGCGGTGAACGGACAGGATCGCGTGCTCGGCATGCTGTCGCTGG
TCCCGTGGGGCCGCACCGGGGTCTCGCTGGAGCTGATGCGCCGCGACCCGAACGGTCCGAACGGCGTGATGGAGCTGATG
ATCTCGCAGCTCGCACTGAACTCCGAACAGCACGGCGTCACCAAGATCTCGTTGAACTTCGCCGTGTTCCGCTCGGTGTT
CGAGGAGGGCGGGCGGATCGGCGCCGGGCCGGTGCTGCGCATGTGGCGCGGTGTGCTGCTGTTCTTTTCGCGATGGTGGC
AGCTGGAGGCGCTGTACCGCTCCAACGTGAAATACCAGCCGCATTGGGTACCAAGGTTTTTCCTGTTCGAGGAGCGCAGG
CAACTGCCGCGGGTCGCGGTGGCCAGCGCGCTCGCCGAGGGCTTCCTGCCGCGGTTCGGGAAAGAACCGGACACGATCAC
CCACACCGGCTCGCACAGCGCGGCGCCCGCGAGCATGACCGGCCTGCACGCCGACGGCAGCCCGCCCGACCTCGACCAGG
TCGAGGGACAGGAACTGCTGCCGCGCCGGCCCGAACAGGTGCGGGTGCGGATGGACAAGCTGGACCGGCTCACCGCCTCC
GGTGTCGAGGCATACCCGGTCGCCTACCCGCCGACCCACAGCGTCGCGGGCGCCCGGCAATCGCCGCGCGGCACCACGGT
CCGGGTGTGCGGCAGGCTGCTGCGCATCCGCGACTACGGCGGCGTGATCTTCGCCGTGCTGCGTGACTGGACCGACGACA
TCCAGCTGGTGATCGATCGGGACCGGGTCGGCGCCGAACGCAGCGCCGAATTCACCGAATTCTTCGACCTCGGTGACCTG
ATCGAGGTCAGCGGGCAGATCGGGCGCAGCCGCCGCGGCGAGCTCTCGCTGCTCGCGGCGGACTGGCGGATGCTCGGCAA
ATGCCTGCATCCCTTGCCGGACAAGTGGAAGGGCCTGTCCGATCCCGAGGCGCGAGTGCGGCAGCGCTACGTCGACATGG
CGATCAACGCCGAAACCCGCGAGGTGCTCGCCAAACGCAGCGCGGTGGTCCGTTCGCTACGCGACACGTTCAACGGCTGG
GGCTACCTCGAGGTGGAGACGCCGATCCTGCAGCAGGTGCACGGCGGCGCCAACGCCACCCCGTTCCTCACCCACATCAA
CGCCTACGACCTCGATCTGTACCTGCGGATCGCGCCCGAGCTGTACCTGAAGCGGCTCTGCGTCGGCGGCATGGAGAAGG
TTTTCGAGATCGGCCGCACCTTCCGCAACGAGGGCGTCGACTTCAGCCACAATCCCGAGTTCACCATCCTCGAGGCCTAC
GAGGCGCACAGCGACTACGAGCGGATGATGCACGCCGCCCGCGAACTCATCCAGAACGCCGCCGTCGCGGCCAACGGTGC
GATGGTGGCGTTGCGGCCGCAGGACGACGGCTCGTTCGAGCAGGTCGACATCTCCGGCGAGTGGGCGGTCAAAACGGTGC
ACGGCGCGGTGTCCGAGGCACTCGGCACCGAGATCACCCCGGCCACCGAGGTCGAGCTGCTGCGCGAACTGTGCGACAAG
GCCGAGGTGCCCTATCAGCACGGCTGGGACGCGGGCCAGGTGGTGCTGGAAATGTACGAGCACCTGGTCGAAGCGCGCAC
CGAGGCGCCGACCTTCTACATCGACTTCCCCACCTCGGTGTCCCCGCTGACCCGCGCGCACCGCAGCATCGCCGGAGTCA
CCGAACGCTGGGACCTGGTCGCCTGGGGCGTCGAACTCGGCACCGCCTACAGCGAACTCACCGATCCGGTGGAGCAGCGA
CGCAGGCTCACCGAACAATCCATGCTCGCCGCCAACGGCGATCCGGAGGCGATGGAACTCGACGAGGACTTCCTGCAGGC
CCTCGAGCACGCGATGCCGCCGACCGGCGGGCTCGGGCTCGGCGTCGACCGGGTGGTCATGCTGATCACGGGGCGCAGCA
TCCGCGAGACACTCCCGTTCCCGCTGGTGAAACCGCGCTGA

Protein sequence :
MTTTQARQHLIEPPADRPTPPVPHRGHGRLAEVPHIAGLVLGVFAVACFLWSLSPTLRYLTQVPRHYIDNYYFDAPDTNL
MWALIVGLLAGALASRKRIAWWLLLGYVSLYALAEGLDFADTGDVNALVAMIVHLAVIGVLVAAWREFYTKVRRGAGWKA
LGVLAGGLTVGFLLGWGLVELFPGSLPQGAQRPGWALYRVTAAVLVDNERFDGHPRPFVNFLLGLFGAIALLAAVIILLR
SQRAANAMTGTDESAIRGLLERSDVEDSLGYFATRRDKAVVFAPSGKAALTYRVELGVCLASGDPVGIREAWPQAIDAWL
RLADQFGWAPAVMGASELGATAYQRAGLSVIRLGDEAILDTRTFSLAGPEMKPVRQAANRLRKHGITVRIRRHRDIPAEE
FRAVIARADAWRDTETERGFSMALGRLGDPLDADCLLVEAVNGQDRVLGMLSLVPWGRTGVSLELMRRDPNGPNGVMELM
ISQLALNSEQHGVTKISLNFAVFRSVFEEGGRIGAGPVLRMWRGVLLFFSRWWQLEALYRSNVKYQPHWVPRFFLFEERR
QLPRVAVASALAEGFLPRFGKEPDTITHTGSHSAAPASMTGLHADGSPPDLDQVEGQELLPRRPEQVRVRMDKLDRLTAS
GVEAYPVAYPPTHSVAGARQSPRGTTVRVCGRLLRIRDYGGVIFAVLRDWTDDIQLVIDRDRVGAERSAEFTEFFDLGDL
IEVSGQIGRSRRGELSLLAADWRMLGKCLHPLPDKWKGLSDPEARVRQRYVDMAINAETREVLAKRSAVVRSLRDTFNGW
GYLEVETPILQQVHGGANATPFLTHINAYDLDLYLRIAPELYLKRLCVGGMEKVFEIGRTFRNEGVDFSHNPEFTILEAY
EAHSDYERMMHAARELIQNAAVAANGAMVALRPQDDGSFEQVDISGEWAVKTVHGAVSEALGTEITPATEVELLRELCDK
AEVPYQHGWDAGQVVLEMYEHLVEARTEAPTFYIDFPTSVSPLTRAHRSIAGVTERWDLVAWGVELGTAYSELTDPVEQR
RRLTEQSMLAANGDPEAMELDEDFLQALEHAMPPTGGLGLGVDRVVMLITGRSIRETLPFPLVKPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 8e-159 45
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 8e-159 45
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 8e-159 45
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 3e-159 45