Gene Information

Name : O3I_021245 (O3I_021245)
Accession : YP_006809182.1
Strain : Nocardia brasiliensis HUJEG-1
Genome accession: NC_018681
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4800513 - 4802000 bp
Length : 1488 bp
Strand : +
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
GTGGAAACCTCGTCCAGCACACCGGGTCCGGCGGCACAGCACTTCCTGTCCGGACCGCACCTGCTCTATCTGGGCGGCGA
GTTCGCCGCCGCCGCGGACGGCCGGACCTTCGGCACCGTCGACCCGTCCACCGGCGCAGCGATCACGCAGGTCGCGCACG
CGGGACCGGCCGACGTATCCGCGGCGGTCGCGGCGGCGCGCGCCGCGCTCGAAGGGCCGTGGGGCGCACTGTCGGCCGCG
GATCGCGGCACCCTCCTCACTCGGTTGGCCGACCTCATCGAGGGCAACGCCGACCAGCTCGCCCAGCTCGAAGCCCTCGA
CGGCGGCAAGCCGATCAGCGTGACCCGCGCGCTCGATATCCCGGCCGCCGCAGCGCAATTCCGCTACTTCGCGGGGTGGC
CGACCAAGCTGGAGGGCGAGACGATCCCGGTCGCGGTGCCGAACACGCTGTGCTACACCCGCAAAGAGCCGGTCGGCGTG
TGCGCGCAGATCATCCCGTGGAACTTCTCGCTGCTGATGGCGGCGTGGAAGATCGGCGCGGCCCTGGCCGCAGGGTGCAC
CGTGGTGGTGAAACCGGCCGAACAGACACCGCTGACCGTACTACGCCTCGCCGAACTCGTTGCGGCGGCCGGGTTTCCGC
CCGGCACGGTCAATGTGCTCACCGGCGACGGCACCACCGGCGCGGCGCTGGTCGAGCATCCCGGCGTCGACAAGATCGTG
TTCACCGGTTCCACCGCCGTGGGGCGCGAGATCGGCGCGAAGGCCGGCGCGCAGCTCAAGCCGGTCACGCTCGAACTGGG
CGGGAAGAGCCCGAACATCATTCTGCCGGACGCCGACCTCGACGCGGCGATCGCCGGCGCCTTCAACGGGATCTACTTCA
ACACCGGCCAGGCGTGCAATGCCGCGTCCCGGCTCTTCGTCCACGAGAGCGTGTTCGACGAGGTCGTCGCGGGACTGTCG
ACGCGGGCCGAGAAGGCACAGGTGGGTCCGGCACTGGACCCGGCCACCGAACTCGGGCCGGTGGTCTCGGCCGAGCAGTA
CCGCCGGGTGCGCGGGTATCTCCAAGACGGCGTCGCCGCGGGGGCGACTCTGAAAGCCGGTACCGTGCCGCCGGTTTCCC
CCGAAGGCGGCTATTTCGTCTCGCCCGCGCTCTTCGTCGACGTCGACCCGCGGATGCGGATCTGCCGTGAGGAGATCTTC
GGGCCGGTGCTCGTGGCCGCACCGTTCGACTGCGTCGACGAGGTGGTGCGGCAGGCCAACGACACGGAATACGGTCTGGC
CGCGGGCATCTGGACCCAGCACCTCGGCCGGGCACACACCCTCGCCGCCCGGCTGCGCGCCGGATCGGTCTATCTCAACA
CCTGGGCGCCGGGCGATCCGGCGGCCCCGTTCGGCGGCGTCAAGGCCTCCGGGGTCGGCCGCGAGATGGGCCGCGCGGGC
GTCGAGGCCTATCTCGAGCCGAAAACCGTGTGGGCGACGCTCGCCTGA

Protein sequence :
METSSSTPGPAAQHFLSGPHLLYLGGEFAAAADGRTFGTVDPSTGAAITQVAHAGPADVSAAVAAARAALEGPWGALSAA
DRGTLLTRLADLIEGNADQLAQLEALDGGKPISVTRALDIPAAAAQFRYFAGWPTKLEGETIPVAVPNTLCYTRKEPVGV
CAQIIPWNFSLLMAAWKIGAALAAGCTVVVKPAEQTPLTVLRLAELVAAAGFPPGTVNVLTGDGTTGAALVEHPGVDKIV
FTGSTAVGREIGAKAGAQLKPVTLELGGKSPNIILPDADLDAAIAGAFNGIYFNTGQACNAASRLFVHESVFDEVVAGLS
TRAEKAQVGPALDPATELGPVVSAEQYRRVRGYLQDGVAAGATLKAGTVPPVSPEGGYFVSPALFVDVDPRMRICREEIF
GPVLVAAPFDCVDEVVRQANDTEYGLAAGIWTQHLGRAHTLAARLRAGSVYLNTWAPGDPAAPFGGVKASGVGREMGRAG
VEAYLEPKTVWATLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-67 46
hpaE AAO17179.1 HpaE Not tested tcd island Protein 8e-64 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-65 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-65 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-65 42
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-63 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-64 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O3I_021245 YP_006809182.1 aldehyde dehydrogenase VFG0082 Protein 7e-64 42