Gene Information

Name : ureC (O3I_019635)
Accession : YP_006808860.1
Strain : Nocardia brasiliensis HUJEG-1
Genome accession: NC_018681
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 4406496 - 4408217 bp
Length : 1722 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
GTGACCGAATTGAGCCGGGCCCGCTACGCGGAACTCTTCGGGCCGACCACCGGTGACCGGATCCGGTTGGCCGACACCGA
TCTGCTGATCGAGATCACCGAAGACCGCAGCGGCGGACCGGGTCTCGCGGGCGAGGAGGCCGTGTTCGGCGGCGGCAAGG
TGCTGCGCGAGTCGATGGGACAGTCCCGCGCGACCCGCGCCGACGGGGCGCCGGACACCGTGATCACCGGCGCGGTGATC
ATCGACCACTGGGGAATCATCAAGGCCGACATCGGCATTCGTGACGGGCGCATCTGCGGCATCGGCAAGGCGGGCAACCC
CGACACGATGAGCGGTGTGCATCCCGACCTCGTCGTCGGCCCGTCCACCGAGATCATCTCCGGCAACGGACGCATCCTCA
CCGCGGGCGCGATCGACTGCCATGTGCACTTCATCTGCCCACAGCTGATGGACGAGGCGCTCGGCGGCGGCATCACCACC
CTGATCGGCGGCGGCACCGGCCCGGCCGAAGGCAGCAAGGCGACCACCGTGACGCCCGGCGCCTGGCATCTGGCCCGCAT
GCTGGAGGCCACCGACGGCTGGCCGCTGAACATCGTGCTGCTCGGCAAGGGCAACACCGTCAGCGCCGACGCCATGTGGG
AGCAATTGCGCGCCGGCGCGGCAGGGTTCAAGCTGCACGAGGATTGGGGCTCCACTCCGGCCGCGATCGACGCCTGCCTG
CGGGTCGCCGACGCCACCGGGGTGCAGGTGGCGCTGCACTCGGACACCTTGAACGAGGCCGGGTTCGTCGAGGACACCCT
CGGCGCCATCGCCGGCCGCGGCATCCACGCCTATCACACCGAGGGTGCGGGCGGCGGGCACGCGCCCGACATCATCACGG
TCGCAGCGCATCTCAACGTGTTGCCCAGCTCGACCAATCCGACCCGCCCGCACACGGTCAACACCCTCGACGAGCATCTC
GACATGCTCATGGTGTGCCATCATCTCAGCGCGTCCATCCCCGAGGATCTGGCGTTCGCGGAGAGCCGGATCCGGCCGTC
CACCATCGCCGCCGAGGATCTGCTGCACGATCTCGGCGCGATCTCCATGATCGGCAGCGATTCCCAGGCGATGGGCCGCA
TCGGTGAGGTGGTGCTGCGCACCTGGCAGACCGCGCACGTGATGAAACGCCGCCGCGGCGCGCTGCCCGGCGACGGCGCC
GCCGACAATGCCCGGGTGCAGCGCTACATCGCGAAATACACCATCTGCCCGGCCGTCGCGCACGGACTGGACCACGAGAT
CGGCTCGGTCGAGGTCGGCAAGCTGGCCGATCTGGTGCTGTGGGAGCCCGCCTTCTTCGGGGTGCGCCCGCACGCCGTGC
TCAAGGGCGGCGCGATCGCCTGGGCCGCGATGGGTGACGCGAACGCGTCCATCCCGACCCCGCAGCCGGTGCTGCCGCGC
CCCATGTTCGGCGCCGCCCCGCTGGCCGCCGCTGCCACCTCCCTGCATTTCGTCTCCGAGCAGGCGATCGAGGACGGCCT
CGCCGACCGCCTGCGCGTGCACCGAAAACTGGCCCCGGTCAAGAACGTTCGCGCTCGCACCAAGGCCGACATGCCGCACA
ACGACGCCATGCCGCGCATCGAGGTGGACCCCGACACCTTCACCGTCCGCATCGACGGCGAGGTCTGGACCGAGCAACCC
GCGACCGAACTCCCCATGGCCCAACGCTATTTCCTCTTCTGA

Protein sequence :
MTELSRARYAELFGPTTGDRIRLADTDLLIEITEDRSGGPGLAGEEAVFGGGKVLRESMGQSRATRADGAPDTVITGAVI
IDHWGIIKADIGIRDGRICGIGKAGNPDTMSGVHPDLVVGPSTEIISGNGRILTAGAIDCHVHFICPQLMDEALGGGITT
LIGGGTGPAEGSKATTVTPGAWHLARMLEATDGWPLNIVLLGKGNTVSADAMWEQLRAGAAGFKLHEDWGSTPAAIDACL
RVADATGVQVALHSDTLNEAGFVEDTLGAIAGRGIHAYHTEGAGGGHAPDIITVAAHLNVLPSSTNPTRPHTVNTLDEHL
DMLMVCHHLSASIPEDLAFAESRIRPSTIAAEDLLHDLGAISMIGSDSQAMGRIGEVVLRTWQTAHVMKRRRGALPGDGA
ADNARVQRYIAKYTICPAVAHGLDHEIGSVEVGKLADLVLWEPAFFGVRPHAVLKGGAIAWAAMGDANASIPTPQPVLPR
PMFGAAPLAAAATSLHFVSEQAIEDGLADRLRVHRKLAPVKNVRARTKADMPHNDAMPRIEVDPDTFTVRIDGEVWTEQP
ATELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-155 64
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-155 64
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-150 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-150 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-150 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-150 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_006808860.1 urease subunit alpha VFG0270 Protein 3e-136 56