Gene Information

Name : O3I_001635 (O3I_001635)
Accession : YP_006805264.1
Strain : Nocardia brasiliensis HUJEG-1
Genome accession: NC_018681
Putative virulence/resistance : Resistance
Product : beta-lactamase AST-1 precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 377763 - 378683 bp
Length : 921 bp
Strand : -
Note : COG2367 Beta-lactamase class A

DNA sequence : 
ATGATTCGGTTCACACGTGATACCCGGGTGGCGTTGGCCGCCGCCGCGCTGGTCCTGCCGCTGCTCGCCGGCTGCGGTAC
CGATTCCCCTGCGGCACAGACCGAATCAGCCGTGGCGAGCACCGCGGCCGTGGCCGCTCCCGCCGAACTGACTGCGCTGG
AACAGCAGTACGACGCCCAGCTCGGGCTGTTCGCCGTCGACACCGGCAGTGGGAAGACGCTGACCAATCGCGCCGACCAG
CGCATGCCCTTCCTGTCCACCTTCAAAGGGCTCGCTGCGGGCGCACTGCTGAAGGCGCACCCGCTCGCCACCGGATACTT
CGACAAGGTCGTGCATTTCACCGAAGCCGACCTGGTCACCTATTCGCCGGTCACCAGCACCAAAGTGGCCGAGGGCATGA
CCATCGCCCAGATAGCCGACGCCGCGATCACCCAGAGCGACAACACCGCGGGCAACCTGCTGCTTCGCGAACTCGGTGGG
CCGCAAGGACTCACCGCCTTTCTGCGCACCCTCGGCGACCAGGTCAGCCGCCTCGACCGCTGGGAACCGGATCTCAACAC
CGCCCTGCCCGACGATGAACGCGACACCACCACCCCCGCCGCGCTCGCCGCCGACTACCGCGCCTTGGTCCTGGGCGATG
CCCTGGGCGCTCCCGAACGCGACCAGCTCACCAAGTGGCTGAAGGCGAACACCACCGGCGACAAGCGCATTCGCGCGGGC
GTCCCGGCAGGCTGGACCACCGGCGACAAAACCGGCACCGGCGACTACGGCATGGCCAACGACGCGGCCGTCACCTGGCC
CGACGGCGGCCGCGCCCCCCTTGTCATCGCCATCCAAACCCGCAAATCCACCACAGCAGCCGAACCCAGCAACGACCTCG
TCGCCGCCGCCACCAAACTCGTCGTCGAAAAGCTGCGCTGA

Protein sequence : 
MIRFTRDTRVALAAAALVLPLLAGCGTDSPAAQTESAVASTAAVAAPAELTALEQQYDAQLGLFAVDTGSGKTLTNRADQ
RMPFLSTFKGLAAGALLKAHPLATGYFDKVVHFTEADLVTYSPVTSTKVAEGMTIAQIADAAITQSDNTAGNLLLRELGG
PQGLTAFLRTLGDQVSRLDRWEPDLNTALPDDERDTTTPAALAADYRALVLGDALGAPERDQLTKWLKANTTGDKRIRAG
VPAGWTTGDKTGTGDYGMANDAAVTWPDGGRAPLVIAIQTRKSTTAAEPSNDLVAAATKLVVEKLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaCTX-M2 ACF06162.1 beta-lactamase CTX-M2 Not tested Tn5036-like Protein 4e-27 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY822595.1.gene1.p01 Protein 9e-32 49
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor EF581888.1.gene1.p01 Protein 4e-31 49
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY847143.1.gene1.p01 Protein 6e-31 49
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY847145.1.gene1.p01 Protein 9e-31 49
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AF395881.gene.p01 Protein 6e-38 49
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor EU729727.1.gene1.p1 Protein 4e-38 49
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor FJ234412.1.gene1.p01 Protein 7e-38 49
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor GQ140348.1.gene1.p01 Protein 9e-38 49
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AF174129.3.gene9.p01 Protein 5e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY143430.1.gene1.p01 Protein 8e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor HM755448.1.gene1.p01 Protein 6e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY847147.1.gene1.p01 Protein 7e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AF252622.2.gene2.p01 Protein 4e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor FJ907381.1.gene1.p01 Protein 6e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor FJ214367.1.gene1.p1 Protein 6e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor DQ211987.1.gene1.p01 Protein 4e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY156923.1.gene1.p01 Protein 5e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor FJ214368.1.gene1.p1 Protein 3e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY029068.1.gene1.p1 Protein 5e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor EF418608.1.gene1.p01 Protein 8e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor JF274247.1.gene1.p01 Protein 6e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor HQ398215.1.gene1.p01 Protein 2e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor HQ833652.1.gene1.p01 Protein 7e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AJ416345.gene.p01 Protein 5e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor EU136031.3.gene1.p3 Protein 6e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY847146.1.gene1.p01 Protein 6e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AF325133.1.gene1.p1 Protein 4e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor FJ214366.1.gene1.p1 Protein 5e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY033516.1.gene2.p01 Protein 1e-30 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY847144.1.gene1.p01 Protein 5e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor JF274246.1.gene1.p01 Protein 6e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor HQ833651.1.gene1.p01 Protein 2e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor HQ913565.1.gene1.p01 Protein 6e-31 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor JF274242.1.gene1.p01 Protein 1e-30 48
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AF367983.gene.p01 Protein 3e-37 47
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor HM066995.1.gene1.p01 Protein 7e-38 47
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY034847.1.gene1.p01 Protein 4e-38 47
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor HQ641421.1.gene1.p01 Protein 6e-38 47
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor EU555534.1.gene1.p01 Protein 5e-38 47
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AF297554.1.gene1.p1 Protein 4e-38 47
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AY178993.1.gene1.p01 Protein 1e-31 42
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AF135373.1.gene1.p01 Protein 1e-31 42
O3I_001635 YP_006805264.1 beta-lactamase AST-1 precursor AF275256.gene.p01 Protein 5e-33 41