Gene Information

Name : O3I_007905 (O3I_007905)
Accession : YP_006806518.1
Strain : Nocardia brasiliensis HUJEG-1
Genome accession: NC_018681
Putative virulence/resistance : Virulence
Product : (2,3-dihydroxybenzoyl)adenylate synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1807529 - 1809169 bp
Length : 1641 bp
Strand : +
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
ATGACGCTCGACGGATTCACGCCCTGGCCATCGGAGTTCGCCGCGCGGTATCGCCAACTCGGCTACTGGGGCACCGACAC
CCTGGCCGAGCTACCCCGGCGCTGGGCCGAGACATTCGGTGCCGCAACGGCATTGGTGCACTACGACACCGGCGTCCGGA
TGGATTACGCGGAACTCGATCGGCGCATCGACCGGATGGCGGCCGGGTTCCGGGCACACGGTATCGAGGCCGGGGATCGG
GTCGTGGTCCAACTGCCCAACCATCCGGAGTTCGTCGTCACGGTGTTCGCCCTCATCCGGCGCGGCGCCATCCCGGTCTT
CGCGCTGCTGGCGCACCGCGGCAACGAGATCCGGCATCTCTGCCGCAGCGTCGACGCCACCGGTTTCGTCACGTCGGCGC
ACTATCGCGGCTTCGATCATCGGGAACTCGCGGTGGACGCGCTGAAGAACTGTCAGACCCTGCGGACGGTTTTCGTCGCG
GGCGAAGCGGACGACGGGGTCGAGTCCGCGGTGTCGGATCGGTTCGTCGCGCTGGCCGAGGTCGACGCGGCGCCCGCCGC
CTTTCCCGCGCCGCACCCGTCGGAGGTGGCCTTCTTCCTGTTGTCCGGCGGGACGACGGCGATGCCCAAGCTGATCGGCC
GCACCCACTACGACTACTGCTATCAGACCCGAGTTCTGGCGGATCTGGTGCAGTTGACCGCGGGGGACGTCTATTTGGCG
GCGCTGCCGGTGGAATTCAACTTCACCTGGGGATCGCCGGGTGTGGTGGGCACGCTGTGCCGGGGCGGCACCGTGGTGCT
GGTCGACGACCCGAATCCGGACGATTGCTTCGCCGCGATCGACCGGGAGCAGGTCACCGTCACCTCGCTGGTGCCCGCGA
TGGCGCAGCTGTGGCTGGAGATCGCGGAGCTGCAACCACCGCGGCTCTCGACGTTGCGCCTGCTGCAGATCGGTGGCGCG
CCGCTGCAACGCAGTGTCGCCGAACGTGTTTCCCCCACCCTGGGTTGTGCGCTGCAACAGGTGTTCGGCATGGCCGAGGG
GTTGCTCAGCGTGACCCGGCTCGACGATCCGGTCGAGACCGTGCTCGGCACGCAGGGACGGCCGATCTCGCCCGGTGACG
AGATCCGCCTGGTCGACGACGCCGATGCCGACGTGCCGCTCGGACACACCGGCGAGCTGCTCGCCCGCGGTCCGTACACG
CTGCGCGGGTATTTCCAAGCGCCGGAACACAATCAGAACTCCTTCACACCGGACGGCTTCTTCCGGACCGGCGATCTGGC
GCGCCTGAGCGCCGCGGGGAATCTCGTGATCGAGGGCCGCCGCAAGGACATCGTGATCCGCGGCGGCAACAAGATCTCGG
CCACCGAACTGGAGGGGTACCTGCTCGCGCATCCCGCGGTCAGCCGGGTGGTCGTGGTGCCGGTGCCCGATGCCGACCTC
GGTGAGGCGATCTGCGTGTGCGTGCAGCCGATCGCCGCGCCGCCCACGCTCGCGGAGCTACGAGAGTTGTTGCAACGCAG
CGGAGTAGCCGAATACAAATGGCCGGATCGGCTGGCGATCGTGACCGCGCTGCCGCTGACCGGTCTCGGCAAAGTCGACA
AGGCCGCCCTGGTGCGGGCCGTGCTCGCGGTGGGGCGGTGA

Protein sequence : 
MTLDGFTPWPSEFAARYRQLGYWGTDTLAELPRRWAETFGAATALVHYDTGVRMDYAELDRRIDRMAAGFRAHGIEAGDR
VVVQLPNHPEFVVTVFALIRRGAIPVFALLAHRGNEIRHLCRSVDATGFVTSAHYRGFDHRELAVDALKNCQTLRTVFVA
GEADDGVESAVSDRFVALAEVDAAPAAFPAPHPSEVAFFLLSGGTTAMPKLIGRTHYDYCYQTRVLADLVQLTAGDVYLA
ALPVEFNFTWGSPGVVGTLCRGGTVVLVDDPNPDDCFAAIDREQVTVTSLVPAMAQLWLEIAELQPPRLSTLRLLQIGGA
PLQRSVAERVSPTLGCALQQVFGMAEGLLSVTRLDDPVETVLGTQGRPISPGDEIRLVDDADADVPLGHTGELLARGPYT
LRGYFQAPEHNQNSFTPDGFFRTGDLARLSAAGNLVIEGRRKDIVIRGGNKISATELEGYLLAHPAVSRVVVVPVPDADL
GEAICVCVQPIAAPPTLAELRELLQRSGVAEYKWPDRLAIVTALPLTGLGKVDKAALVRAVLAVGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-89 45
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-89 45
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 6e-90 45
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 8e-90 45
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-90 45
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 7e-90 45
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-90 45
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-90 45
ybtE CAA21394.1 - Virulence HPI Protein 7e-90 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O3I_007905 YP_006806518.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG1817 Protein 6e-97 46
O3I_007905 YP_006806518.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0168 Protein 4e-99 45