Gene Information

Name : spaP (O3K_05160)
Accession : YP_006777750.1
Strain : Escherichia coli 2011C-3493
Genome accession: NC_018658
Putative virulence/resistance : Virulence
Product : type III secretion system protein SpaP
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1062740 - 1063405 bp
Length : 666 bp
Strand : +
Note : COG4790 Type III secretory pathway, component EscR

DNA sequence :
ATGTCAAATACCATTTCGCTGATAGCTATACTAACATTATTTACACTATTGCCGTTTATAATAGCATCCGGGACATATTT
TATTAAATTCTCGATTGTTTTTGTTATTGTCCGAAACGCGCTGGGGCTTCAGCAAGTGCCATCAAATATGACACTTAATG
GGGTTGCTTTGCTATTGTCAATGTTTGTAATGATGCCGGTTGGGACGGAAATATATTATAACAGTCAGAATGAGAATCTT
TCATTCAATAATGTAGCGTCGGTTGTTAATTTTGTTGAGACAGGCATGAGTGGTTATAAATCATATTTGATAAAATATTC
TGAACCTGAGTTGGTTAGCTTTTTTGAAAAGATTCAGAAGGTGAATAGTTCTGAAGACAATGAAGAGATAATCGATGATG
ATAATATTTCAATTTTCTCGTTACTGCCCGCATATGCATTGAGTGAGATAAAAAGTGCATTTATTATAGGTTTTTATATC
TATTTACCCTTTGTCGTAGTGGATCTGGTTATATCCAGCGTTCTGTTAACGTTAGGTATGATGATGATGAGCCCGGTAAT
CATATCTACACCGATAAAATTAATTCTATTTGTCGCTATGGACGGTTGGACAATGTTATCAAAAGGACTCATTTTACAAT
ATTTTGACCTATCCATTAATCCCTGA

Protein sequence :
MSNTISLIAILTLFTLLPFIIASGTYFIKFSIVFVIVRNALGLQQVPSNMTLNGVALLLSMFVMMPVGTEIYYNSQNENL
SFNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQKVNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYI
YLPFVVVDLVISSVLLTLGMMMMSPVIISTPIKLILFVAMDGWTMLSKGLILQYFDLSINP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
epaP AAZ31293.1 EpaP Virulence ETT2 Protein 3e-64 100
spaP NP_311752.1 surface presentation of antigens protein SpaP Not tested LIM Protein 8e-63 99
spaP YP_217809.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 7e-45 66
spaP NP_461811.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 7e-45 66
spaP NP_457284.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 2e-44 65
spaP NP_806493.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 2e-44 65
spaP AAS66865.1 SpaP Not tested SSR-2 Protein 2e-44 57
ysaR AAS66846.1 YsaR Not tested SSR-1 Protein 6e-38 56
escR AAC38369.1 EscR Virulence LEE Protein 3e-24 43
escR AAC31528.1 L0049 Virulence LEE Protein 6e-25 43
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 6e-25 43
ECs4583 NP_312610.1 type III secretion system protein Virulence LEE Protein 8e-25 43
escR AAK26700.1 EscR Virulence LEE Protein 5e-25 43
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 8e-25 43
escR AAL57527.1 EscR Virulence LEE Protein 5e-25 43
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 8e-25 43
escR CAC81847.1 EscR protein Virulence LEE II Protein 5e-25 43
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 7e-25 43
escR CAI43889.1 EscR protein Virulence LEE Protein 5e-25 43
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 7e-25 43
lscR AAO18040.1 LscR Virulence TTSS locus Protein 2e-24 42
escR AFO66317.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 5e-22 41
escR AFO66400.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 5e-22 41
unnamed AAL06354.1 EscR Virulence LEE Protein 2e-23 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaP YP_006777750.1 type III secretion system protein SpaP VFG0551 Protein 3e-45 66
spaP YP_006777750.1 type III secretion system protein SpaP VFG2455 Protein 1e-43 61
spaP YP_006777750.1 type III secretion system protein SpaP VFG1773 Protein 2e-44 60
spaP YP_006777750.1 type III secretion system protein SpaP VFG1012 Protein 2e-39 58
spaP YP_006777750.1 type III secretion system protein SpaP VFG0394 Protein 7e-26 45
spaP YP_006777750.1 type III secretion system protein SpaP VFG0188 Protein 7e-25 44
spaP YP_006777750.1 type III secretion system protein SpaP VFG0715 Protein 1e-24 43
spaP YP_006777750.1 type III secretion system protein SpaP VFG0827 Protein 3e-25 43
spaP YP_006777750.1 type III secretion system protein SpaP VFG0044 Protein 4e-24 41