Gene Information

Name : O3K_00505 (O3K_00505)
Accession : YP_006776837.1
Strain : Escherichia coli 2011C-3493
Genome accession: NC_018658
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 85541 - 86014 bp
Length : 474 bp
Strand : -
Note : COG0262 Dihydrofolate reductase

DNA sequence :
TTGAAAATTTCATTGATTTCTGCAACGTCAGAAAATGGCGTAATCGGTAATGGCCCTGATATCCCATGGTCAGCAAAAGG
TGAGCAGTTACTCTTTAAAGCGCTCACATATAATCAGTGGCTCCTTGTTGGAAGGAAAACATTTGACTCTATGGGTGTTC
TTCCAAATCGAAAATATGCAGTAGTGTCGAGGAAAGGAATTTCAAGCTCAAATGAAAATGTATTAGTCTTTCCTTCAATA
GAAATCGCTTTGCAAGAACTATCGAAAATTACAGATCATTTATATGTCTCTGGTGGCGGTCAAATCTACAATAGTCTTAT
TGAAAAAGCAGATATAATTCATTTGTCTACTGTTCACGTTGAGGTTGAAGGTGATATCAATTTTCCTAAAATTCCAGAGA
ATTTCAATTTGGTTTTTGAGCAGTTTTTTTTGTCTAATATAAATTACACATATCAGATTTGGAAAAAAGGCTAA

Protein sequence :
MKISLISATSENGVIGNGPDIPWSAKGEQLLFKALTYNQWLLVGRKTFDSMGVLPNRKYAVVSRKGISSSNENVLVFPSI
EIALQELSKITDHLYVSGGGQIYNSLIEKADIIHLSTVHVEVEGDINFPKIPENFNLVFEQFFLSNINYTYQIWKKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA1 AAX48777.1 DfrA1 trimethoprim-insensitive dihydrofolate reductase Not tested SGI2 Protein 1e-51 72
dfrI CAJ77029.1 dihydrofolate reductase type I Not tested AbaR1 Protein 1e-51 72
dfrA1 AGF34987.1 DfrA1 dihydrofolate reductase Not tested SGI1 Protein 1e-51 72
dfrA15 AGK07099.1 DfrA15 dihydrofolate reductase Not tested SGI1 Protein 6e-53 72
dfrA5 AET25387.1 dihydrofolate reductase Not tested PAGI-2(C) Protein 1e-46 66
dfrA5 AFG30110.1 dihydrofolate reductase Not tested PAGI-2 Protein 1e-46 66
dfrA1 ADZ05803.1 trimethoprim-insensitive dihydrofolate reductase Not tested AbaR3 Protein 8e-49 66
unnamed AEL12695.1 DfrA5 Not tested AbaR21 Protein 8e-49 66