Gene Information

Name : guaA (NSED_00640)
Accession : YP_006774882.1
Strain : Candidatus Nitrosopumilus sp. AR2
Genome accession: NC_018656
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 111756 - 113279 bp
Length : 1524 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGGATAAAATTGTAGTTTTAGATTTTGGATCACAGTATAGCCATTTAATCTGTAGGAGAATTCGAGAGTTTTCTGTCTA
TGCAGAACTAGTTCCTTATGATATCAGTTATGAGGAATTACAAAAAATAAATCCTACAGGGATAATTTTTTCGGGTGGCC
CATCCAGTGTTTATAATTCAGATGCACCTATTCCAGAAAATAAAATTTTTGATATGAACTTACCATTACTTGGAATCTGT
TATGGTCATCAACTGATTGTTAACAAATATGGAGGAAAAGTAAAAAGGGCAAACAAAGAATATGGTTCATCATTACTAAC
AATCGATAGTAATGAAGACCTTCTAAACGGAATTGGTGAATCAATCAGAGCATGGATGAGTCATGGGGATGAGGCAGAGC
AAATTCCAGAGGGTTTCCAAGTAATAGGTCATACTGAAAGTGCAAAGGCAGCTGCAATTGCATTAAAAGAAAAATCAATC
TATGGAATTCAATTTCATCCTGAGGTGGTACATACAGAGCAAGGTACAGAAATTCTAAAAAATTTTGTTTTGAAAGTTTG
TGGTGCCAAACAAGATTGGACCATGGAAGGTTTTATCGATACAGCTATTGAAAAAATCTCAAAAATCGATGGAAATGTGC
TTTGTGGAGTTAGTGGTGGCATAGATTCTACAGTAGTTGCATTGCTTATTCACAAAGCAATCGGAGATAGACTAAAGTGT
GTTTTTGTTGATAACGGCTTGCTACGATTGAATGAAGAAAAAGAGATTGAGGAAATGTTCAAAGATAATTTCAAAGTAGA
TTTTACAGCAGTAAATGCTGCAGATGCATTTCTTGGAAAACTCAAAGGAGTAGAAGATCCTGAAAAGAAAAGAATGATTG
TTGGAGAAGAATTTATTCAGGTATTTACTGAATTTGCTAAAGGAAATGGTCCATTCAAATGGTTAGCTCAAGGTACATTG
TATCCAGATGTGATTGAAAGTGGAGTATCAAAAGGACCCGCTGCAGTAATAAAATCACATCATAATGTAGGAGGACTACC
AGAATGGCTGAATTTAGAAATTTTAGAGCCATTAAGGGACTTGTATAAAGATGAAGTAAGGAAAATTGCCAAAATTCTTC
AAGTTCCAGAAAAACTTTTCATGAGACACCCATTTCCAGGTCCAGGTTTGTCAGTAAGGATAATCGGAGAAGTTACTCCA
ACAAAACTAGAGATTTGTAAAGTAGCCAGTAAAATAGTCGAAGAGGAGTTAATTGAAGCAGGTTTGTATGAAAAAGTATG
GCAGGCATATGCAGCAGTAGGTGATGATAGGGCAGTGGGAGTTGTTGGAGATGAACGCAGATATGGAAATATTGTAATGA
TTAGAGTTGTAGATTCAGTTGATGCAATGACCGCAGATTGGACAAGATTGCCACATGGATTATTAGAAAAAATGAGTAAT
AGAATAACAAATGAGATTGAAGATGTTACGTGGGTCACCTATACAATATCAAGTAAACCACCAGCAACAATTGAACCACA
ATAA

Protein sequence :
MDKIVVLDFGSQYSHLICRRIREFSVYAELVPYDISYEELQKINPTGIIFSGGPSSVYNSDAPIPENKIFDMNLPLLGIC
YGHQLIVNKYGGKVKRANKEYGSSLLTIDSNEDLLNGIGESIRAWMSHGDEAEQIPEGFQVIGHTESAKAAAIALKEKSI
YGIQFHPEVVHTEQGTEILKNFVLKVCGAKQDWTMEGFIDTAIEKISKIDGNVLCGVSGGIDSTVVALLIHKAIGDRLKC
VFVDNGLLRLNEEKEIEEMFKDNFKVDFTAVNAADAFLGKLKGVEDPEKKRMIVGEEFIQVFTEFAKGNGPFKWLAQGTL
YPDVIESGVSKGPAAVIKSHHNVGGLPEWLNLEILEPLRDLYKDEVRKIAKILQVPEKLFMRHPFPGPGLSVRIIGEVTP
TKLEICKVASKIVEEELIEAGLYEKVWQAYAAVGDDRAVGVVGDERRYGNIVMIRVVDSVDAMTADWTRLPHGLLEKMSN
RITNEIEDVTWVTYTISSKPPATIEPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-120 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-120 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-120 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-109 46