Gene Information

Name : O3M_22875 (O3M_22875)
Accession : YP_006772189.1
Strain : Escherichia coli 2009EL-2050
Genome accession: NC_018650
Putative virulence/resistance : Unknown
Product : Prophage integrase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4714826 - 4716088 bp
Length : 1263 bp
Strand : +
Note : COG0582 Integrase

DNA sequence :
ATGGCACTGACTGACGCAAAAATCCGGGCTGCAAAGCCCACTGACAAGGCTTATAAACTCACTGACGGGGCCGGCATGTT
CCTGCTGGTTCATCCTAATGGTTCCCGTTACTGGCGTCTCCGTTATCGTATTCTGGGTAAGGAGAAGACTCTGGCACTTG
GTGTGTATCCAGAAGTTTCTCTCTCCGAAGCTCGTACAAAACGGGATGAGGCCCGAAAACTGATTTCAGAGGGGATTGAC
CCTTGCGAACAGAAAAGAGTTAAAAAAGTTGTCCCTGATTTACAGCTCTCTTTTGAACATATTGCACGACGCTGGCATGC
CAGTAATAAACAATGGGCACAATCACACAGCGATAAAGTACTCAAAAGCCTCGAGACACACGTTTTCCCCTTTATCGGCA
ACCGGGATATCACAACACTCAATACCCCGGACCTGCTTATCCCTGTTCGTGCTGCAGAAGCAAAACAAATTTATGAAATC
GCCAGTCGTCTGCAGCAAAGAATATCTGCTGTAATGCGTTACGCCGTACAGTCTGGCATCATCAGATATAACCCGGCTCT
GGATATGGCTGGTGCATTGACCACGGTAAAACGCCAGCATCGCCCTGCTCTGGAGCTTTCACGCCTGCCTGAACTTCTGT
CGCGTATTGACGGTTATAAAGGCCAGCCTGTCACCCGACTGGCAGTTATGCTGAATTTACTGGTTTTTATTCGTTCCAGT
GAACTCAGATATGCCCGCTGGTCGGAAATTGATATTGACAATTCCATGTGGACTATTCCAGCCGAACGCGAACCTCTGCC
AGGCGTAAAATTCTCACACCGGGGATCCAAGATGCGAACACCACATCTTGTGCCACTCAGCAAACAGGTTGTAGCCATAC
TGGCAGAACTTCAGACATGGGCTGGTGAAAATGGTCTGATCTTTACGGGTGCACATGACCCGCGTAAACCAATCAGTGAA
AATACTGTAAATAAAGCCCTGAGGGTGATGGGGTATGACACAACCCAGGAAGTCTGTGGCCATGGATTCCGGGCGATGGC
GTGCAGTGCATTGATTGAATCAGGTTTGTGGTCCCGCGATGCTGTGGAACGTCAGATGAGCCATCAGGAGCGTAATGGTG
TACGTGCTGCGTATATCCATAAAGCAGAACATCTGGAAGAACGGCGACTGATGTTGCAATGGTGGGCCGATTTTCTAGAT
GCGAACCGGGAGAAGGGTATCAGCCCGTTTGAATATGCAAAGATTAACAATCCATTAAAATAG

Protein sequence :
MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRILGKEKTLALGVYPEVSLSEARTKRDEARKLISEGID
PCEQKRVKKVVPDLQLSFEHIARRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEAKQIYEI
ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALELSRLPELLSRIDGYKGQPVTRLAVMLNLLVFIRSS
ELRYARWSEIDIDNSMWTIPAEREPLPGVKFSHRGSKMRTPHLVPLSKQVVAILAELQTWAGENGLIFTGAHDPRKPISE
NTVNKALRVMGYDTTQEVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLMLQWWADFLD
ANREKGISPFEYAKINNPLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 0.0 100
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 0.0 100
int AAK00456.1 Int Not tested SHI-1 Protein 5e-180 100
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 0.0 99
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 0.0 99
int AAK16198.1 Int Not tested PAI-I AL862 Protein 0.0 99
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 0.0 99
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 0.0 99
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 0.0 98
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 0.0 98
int AAL51028.1 CP4-like integrase Not tested LEE Protein 0.0 98
int-phe AAL60261.1 Int-phe Not tested LEE Protein 0.0 98
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 0.0 98
int AAL51003.1 CP4-like integrase Not tested LEE Protein 0.0 98
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 0.0 98
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 0.0 98
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 0.0 98
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 0.0 98
int CAC81896.1 integrase Not tested LEE II Protein 5e-177 98
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 0.0 97
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 0.0 97
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 3e-130 68
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 2e-123 61
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 2e-123 61
int CAB59974.1 integrase Not tested HPI Protein 1e-109 56
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 2e-76 55
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 4e-109 55
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 4e-109 55
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 6e-111 55
int YP_002346908.1 integrase Not tested HPI Protein 2e-108 55
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 2e-108 55
int2 NP_993013.1 integrase Not tested HPI Protein 2e-108 55
int CAA21384.1 - Not tested HPI Protein 2e-108 55
int CAA08754.1 integrase Not tested HPI Protein 6e-109 55
unnamed AAD17660.1 unknown Not tested HPI Protein 5e-106 54
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 7e-84 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 1e-96 52
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 3e-73 43
int AAD44730.1 Int Not tested SHI-2 Protein 7e-80 42
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-80 42
int CAC39282.1 integrase Not tested LPA Protein 1e-80 42
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 4e-79 41
ECs4534 NP_312561.1 integrase Not tested LEE Protein 4e-79 41
int AAC31482.1 CP4-like integrase Not tested LEE Protein 3e-79 41
int ACU09430.1 integrase Not tested LEE Protein 3e-79 41
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 3e-78 41
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 2e-78 41
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 3e-78 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O3M_22875 YP_006772189.1 Prophage integrase VFG0626 Protein 0.0 100
O3M_22875 YP_006772189.1 Prophage integrase VFG1693 Protein 0.0 97
O3M_22875 YP_006772189.1 Prophage integrase VFG1536 Protein 2e-130 68
O3M_22875 YP_006772189.1 Prophage integrase VFG0783 Protein 2e-79 41
O3M_22875 YP_006772189.1 Prophage integrase VFG0598 Protein 1e-78 41