Gene Information

Name : O3M_01170 (O3M_01170)
Accession : YP_006767917.1
Strain : Escherichia coli 2009EL-2050
Genome accession: NC_018650
Putative virulence/resistance : Virulence
Product : long polar fimbrial outer membrane usher protein LpfC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 225380 - 227911 bp
Length : 2532 bp
Strand : +
Note : COG3188 P pilus assembly protein, porin PapC

DNA sequence :
ATGCATTGGATGCATTTACCTCTCTATCACTACAGAGCGCATTTTTCCTTCTCTCTGCTGGCATTAACGATTGCCAGCTC
GTTACCTGCGTATGGCGGAAAATTTAACCCTAAATTTCTCGAAAACGTTCAGGGTATCGATCAACACATCGACTTGTCGG
TATACGACTCACCTGTCGGCCAGCAAATCCCCGGTAAATACCGGGTTTCGGTGTTTGTAAACGAAGAAAAAATGGCTTCC
CGGACGCTGGATTTTAGTACCGCCAGCGAAGCGAAACGCAAAGCCAGCGGTGAGTCGCTTATGCCTTGCCTTAGCCGGGT
GCAACTGGAAGAAATGGGCGTGCGCGTTGACAGCTTTCCGGCGCTGAAGATGTCACCACCAGAAGCCTGCGTAGCGTTTG
ATGAAATCATTCCCCAGGCCACCAGCCGCTTTGATTTTAATACTCAGACGCTGCATCTTTCCTTTCCACAGGCGGCAATG
ATGATGACCGCTCGCGGCACGGTTGATCCTTCTCGCTGGGACGAAGGAATACCTGCGCTGTTGCTGGATTACAGCTTTAG
TGGCAGCAATGGACGCAATGAAGGTACAGGTTCATCTTCAGATTCGACCAGTGACAGTTATTACCTGAACCTGCGCAGCG
GTTTGAACGTTGGTCCGTGGCGTTTACGTAATAACAGTATCTGGAACCGTACCGATGGCAAAAACCAATGGGATAACGTT
GGTACATCGTTAAACCGGGCAATTATTCCACTTAAATCACAGATAACTCTGGGTGATACCGCCACGCCTGGCGAGATTTT
TGATAGCGTACAAATGCGTGGGGCGTTACTGGCATCCGACGATGAAATGTTGCCGGACAGCCAGCGTGGCTTTGCTCCGG
TAGTGCGCGGCATCGCCAAAAGCAACGCTGAAGTGAGTATCGAACAGAACGGCTATGTCATTTATCGCACTTTTGTTCAG
CCGGGTGCATTTGAGATTAACGATCTCTACGCAACCTCCGGCAGCGGCGACCTGACGGTGATCATTAAAGAAGCCGACGG
AAGTGAACAACGTTTTATCCAGCCGTTTTCGGCGGTGGCGATTTTCCAGCGTGAAGGGTATCTGAAATACAGTCTGGCTG
CCGGTGAATATCGTGCTGGTAATTACGACAGCGATAAACCACATTTCGGGCAGTTTACCGCCATGTACGGCTTGCCGTGG
GGTATGACCGCCTACGGTGGTGCATTGTTGTCGGCAGATTACAGCGCTTTAGCTCTGGGCCTGGGGAAAAACTTCGGTAC
CATTGGCGCAGTATCGGTGGATGTCACTCAGGCGAAAAGTCAGTTACGCAACAATGAAAAAGAGGAAGGCCAGTCTTATC
GCTTCCTCTATTCGAAAAGTTTTGAGGGTGGCACTGACCTGCGTCTGTTGGGCTACAAATACTCAACCAGCGGCTACTAC
ACCTTCCAGGAAGCAACTGATGTTCGCAGTGACGCCGACAGTGATTACCGCCGTTATCACAAGCGCAGCCAGATACAGGG
CAATATTACCCAGCAACTGGGAGACTACGGCTCGGTTTATTTCAATATGACGCAGCAGGATTACTGGAACGTTGACGGTA
AGGAAAACTCCTTAAGCGCCGGTTATCACGGTCACATTGGTCGGGTGAATTACAGCGTGGCCTATACCTGGACGAGAAGT
CCGGAATGGGAAGAAGACGATCGCTTGTGGTCATTCAGTGTTTCCATCCCTCTGGGGGGCGCGTGGAGCAGTTATCGCAT
GACTACCGACCAGAATGGCAAGACGTCGCAACAGGCCTCTGTTAGCGGCACGTTACTGGAAGATCGTAACCTGAGCTATA
ACGTTCAGCAGGGTTACACCAGTAATGGCGTAGGCTACAGTGGCAGCGTCAACATGGGGTATATGGGTGGCTCTGGTAAC
ATTGACGTAGGCTATAACTATTCTAAAGATAACCAACAGGTTAACTATGGCGTGCGCGGCGGTGTCATCGTTCACAGTGA
AGGTATAACGCTTTCGCAGCCTTTAGGCGAAAGTCTGGCGATTGTTTCTGCACCGGGCGCGCGTGGTGGACATGTGGTTA
ACAGCAGCGGCGTAGAAGTTGACTGGATGGGCAACGCCGTGGTGCCTTATCTCACACCATATCGTGAAACCATTGTGGAA
TTGCGTAGCGACACGTTGGGGCAAAACGTTGAACTACAGGAAGCGTTCCAGAAAGTCGTGCCTACTCGTGGTGCAGTTGT
GCGTTCCCGCTTTGATACCCGCGTCGGTTACCGTGTGCTGATGAGCTTAAAACAGGCGAATGGCAACGCAGTACCGTTTG
GTGCAACCGCAGCGTTAATTGATGAGAGCAAACCTGCCAGCAGCATTGTGGGTGAAGAAGGACAGCTTTATATCAGCGGG
ATGCCAGAAGAGGGCGAATTGCAGGTGAGCTGGGGGAACGAGCAGGCGCAACGTTGCCGTGTGCCATTCCGCTTGCCAGA
GAACAAGGACAATGCGGCTATCGTGATGGTTAATGCGGTATGCGAGAAATAA

Protein sequence :
MHWMHLPLYHYRAHFSFSLLALTIASSLPAYGGKFNPKFLENVQGIDQHIDLSVYDSPVGQQIPGKYRVSVFVNEEKMAS
RTLDFSTASEAKRKASGESLMPCLSRVQLEEMGVRVDSFPALKMSPPEACVAFDEIIPQATSRFDFNTQTLHLSFPQAAM
MMTARGTVDPSRWDEGIPALLLDYSFSGSNGRNEGTGSSSDSTSDSYYLNLRSGLNVGPWRLRNNSIWNRTDGKNQWDNV
GTSLNRAIIPLKSQITLGDTATPGEIFDSVQMRGALLASDDEMLPDSQRGFAPVVRGIAKSNAEVSIEQNGYVIYRTFVQ
PGAFEINDLYATSGSGDLTVIIKEADGSEQRFIQPFSAVAIFQREGYLKYSLAAGEYRAGNYDSDKPHFGQFTAMYGLPW
GMTAYGGALLSADYSALALGLGKNFGTIGAVSVDVTQAKSQLRNNEKEEGQSYRFLYSKSFEGGTDLRLLGYKYSTSGYY
TFQEATDVRSDADSDYRRYHKRSQIQGNITQQLGDYGSVYFNMTQQDYWNVDGKENSLSAGYHGHIGRVNYSVAYTWTRS
PEWEEDDRLWSFSVSIPLGGAWSSYRMTTDQNGKTSQQASVSGTLLEDRNLSYNVQQGYTSNGVGYSGSVNMGYMGGSGN
IDVGYNYSKDNQQVNYGVRGGVIVHSEGITLSQPLGESLAIVSAPGARGGHVVNSSGVEVDWMGNAVVPYLTPYRETIVE
LRSDTLGQNVELQEAFQKVVPTRGAVVRSRFDTRVGYRVLMSLKQANGNAVPFGATAALIDESKPASSIVGEEGQLYISG
MPEEGELQVSWGNEQAQRCRVPFRLPENKDNAAIVMVNAVCEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 2e-156 43
lpfC YP_006098365.1 fimbrial outer membrane usher protein Not tested Tn2411 Protein 2e-134 41
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 6e-157 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O3M_01170 YP_006767917.1 long polar fimbrial outer membrane usher protein LpfC VFG0454 Protein 0.0 74
O3M_01170 YP_006767917.1 long polar fimbrial outer membrane usher protein LpfC VFG0876 Protein 2e-161 44
O3M_01170 YP_006767917.1 long polar fimbrial outer membrane usher protein LpfC VFG0446 Protein 2e-149 41
O3M_01170 YP_006767917.1 long polar fimbrial outer membrane usher protein LpfC VFG1645 Protein 3e-157 41
O3M_01170 YP_006767917.1 long polar fimbrial outer membrane usher protein LpfC VFG0912 Protein 6e-157 41