Gene Information

Name : LFML04_0795 (LFML04_0795)
Accession : YP_006765989.1
Strain : Leptospirillum ferriphilum ML-04
Genome accession: NC_018649
Putative virulence/resistance : Resistance
Product : mercuric reductase Hg(II) reductase,MerA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 730460 - 732250 bp
Length : 1791 bp
Strand : +
Note : -

DNA sequence : 
ATGAAGAAGCACCCGGGAATCCGGGAGTCGGGGCCTCCTGATTTTTCAAGGACCCTTTTCGAAACGGGCCGGGAACAGGA
CGGGAGAAGATCCTGTTTTCTTCCCGGGTGTATTCTGACAGAAGGAGTGCAGGGCATGAAAAATATCGCGTTTCAGATTC
AGGGAATGACCTGTGACCATTGCGCCCGGACGGTGGAAAGCACCCTCCGGAAGGTTCCCGGTGTTTCCTCGGCCAGCGTG
TCTTTTTCCGCCGGCGGGGGAAGCGCCGAGGTGGGGGACGATCTGTCCCTGCCGGCTCTCGAACAGGCGGTCCGTCAGGT
CGGATATCGTCTGATCCCGGCCGATTCCGTTTCTTCCCGGACAGAAGATTTCTCTTCTCCCAAAGCGGAATCCGGGCGTT
CTGTCGTCATCATCGGGGCGGGATCTGGCGCCTTCGCCGCGGCTCTCCGGGTGATCGAACTCGGAGGACGGGTGACCCTG
ATCGAGCGGGGCACTCTGGGGGGGACCTGCGTCAACGTCGGCTGCGTTCCGTCCAAGATCCTGATCCGTCAGGCGGATCA
TGCCTGGAAACCCCGGACACAGCCGTTCGACGGGATCGAACATCCAAATCCGGGACTTCACCCCCTTCTGCTGAAGAGAC
AGCGGGAAAGACGGGTTCTGGAGCTGCAGGAAGAGAAGTATGCCCGGATTCTCCGGGAGATGCCGCAGGTGACCTTTCTG
GCCGGAAACGCGTCCTTCGTCGATGCCAGCACGGTGCGTGTCCTGCTGAACGGAGGGGAGGAGAGAACGGTCTCGGCCGA
CCGCATCCTGATTGCCACCGGAGGCCGTCCGTCCGTCCCGGAGATCCCGGGACTTTCGGGCACCCCCTACTGGACGTCCA
CGGACGCCCTGTTCTCAGAGACTGTTCCGGCACGGCTGATTGTTCTGGGCAGCGGGTTCGTGGCGGCGGAAATCGGGCAG
TCCCTCCGCCGTCTGGGCGCCCGTGTCACGGTCGTTGGGCGTCGGGGTTCCCTTCTGAACCGGATGGACCCCGATCTGGG
AAAAGGTCTGGAGGGGTACCTTCAGGAGGAGGGGATCCGGTTTGTCTTTCGGGGAGAGCCTCGAAAAGTCGACTATCAAA
AGGGCCTGTTCCGGGTGGATGTCGACGGCGAAACGCTGGAGGCCGAAGCGCTTCTGGTCGCCACGGGAAGGACGCCGAAT
ACGGGAGACCTGGCTCTGGAAAAAGCCGGCGTCTCGACGAACCCGAAGGGCGAGATTGTCGTGAACGAACGGCTGGAAAC
AAACGTGCCCGGCATTTATGCCGTCGGAGACTGCACGAATCTCCCCAAATTCGTCTATGTCGCCGCGGCCGCCGGAACCC
GGGCGGCGACCAACATGATGGGGGACGGGACGGTTTCGCTCGATCTTTCCGTCCTGCCCGAGGTCATTTTCACCGATCCC
CAGGTGGCGGTTGTCGGTCTGACCGGGGAGGACGCCCGGAAGCGGGGCATTGCGGTCGAGATCCGGACAGTGTCCCTCGA
CCAGGTTCCCCGGGCTCTGGCCAACTTCGACACGCGGGGCTGGGTCCGCATGGTGGCGGAAACGACGACCGGACGTCTCC
TGGGTGTCCAGATTCTCGCTCCGGAAGGAGGAGAGGTGATCCAGACGGCGGCCCTGGCCATCAGCGCGGGAAAAACCGTC
CGCGAAATCGGAGATCAGCTTTTTCCATACCTGACCATGGTGGAGAGCCTGAAGCTGTGCGCCCAGTCTTTTCACAAGGA
TGTCCGGCAGCTCTCCTGCTGTGCGGGGTAG

Protein sequence : 
MKKHPGIRESGPPDFSRTLFETGREQDGRRSCFLPGCILTEGVQGMKNIAFQIQGMTCDHCARTVESTLRKVPGVSSASV
SFSAGGGSAEVGDDLSLPALEQAVRQVGYRLIPADSVSSRTEDFSSPKAESGRSVVIIGAGSGAFAAALRVIELGGRVTL
IERGTLGGTCVNVGCVPSKILIRQADHAWKPRTQPFDGIEHPNPGLHPLLLKRQRERRVLELQEEKYARILREMPQVTFL
AGNASFVDASTVRVLLNGGEERTVSADRILIATGGRPSVPEIPGLSGTPYWTSTDALFSETVPARLIVLGSGFVAAEIGQ
SLRRLGARVTVVGRRGSLLNRMDPDLGKGLEGYLQEEGIRFVFRGEPRKVDYQKGLFRVDVDGETLEAEALLVATGRTPN
TGDLALEKAGVSTNPKGEIVVNERLETNVPGIYAVGDCTNLPKFVYVAAAAGTRAATNMMGDGTVSLDLSVLPEVIFTDP
QVAVVGLTGEDARKRGIAVEIRTVSLDQVPRALANFDTRGWVRMVAETTTGRLLGVQILAPEGGEVIQTAALAISAGKTV
REIGDQLFPYLTMVESLKLCAQSFHKDVRQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-105 52
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-105 52
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-105 52
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-105 52
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-105 52
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-105 52
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 1e-101 51
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 2e-101 51
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 3e-99 49
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 6e-102 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LFML04_0795 YP_006765989.1 mercuric reductase Hg(II) reductase,MerA BAC0653 Protein 3e-111 51
LFML04_0795 YP_006765989.1 mercuric reductase Hg(II) reductase,MerA BAC0652 Protein 5e-102 50
LFML04_0795 YP_006765989.1 mercuric reductase Hg(II) reductase,MerA BAC0650 Protein 1e-100 47