Gene Information

Name : ugd (HMPREF1038_00406)
Accession : YP_006742606.1
Strain : Streptococcus pneumoniae gamPNI0373
Genome accession: NC_018630
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.1.1.22
Position : 354621 - 355889 bp
Length : 1269 bp
Strand : +
Note : KEGG: spr:spr0318 1.5e-174 cps2K; UDPglucose 6-dehydrogenase K00012; Psort location: Cytoplasmic, score: 8.87

DNA sequence :
ATGTATAACGAGAGTGTTTTGAGAAAGGAAAAAATTATGAAAATAGCAGTAGCAGGTACAGGATATGTTGGATTATCTAT
TGCAATCTTACTGGCTCAACATCATCAAGTTGTTGCCGTAGATATCATTCCTGAGAAAGTTGAGTTAATCAATAAAAAGA
AGTCCCCTATCCAAGACGATTATATAGAAAAATATCTCGCGGAAAAAGAATTGAATCTCGTAGCTACATTGAATGCAGAG
GAAGCATATGAGAATGCGGATTTTATAGTTATTGCGGCTCCAACTAATTATGATCCGAAAAAAAATTTTTTCGATACATC
TTCAGTCGAGGCTGTCATTGAAGCAGTTATGAAATATAATCCTGATGCAATTATAATAATTAAAAGTACTGTTCCTGTTG
GATATACAAAGTCAGTACGGAGGAAATTTCTTACAGACAATATTATGTTTAGTCCTGAGTTTTTACGGGAGTCAAAAGCG
TTATATGATAACCTATATCCGAGTCGAATTATTATAGGTACAGATAAAGATGATAAAGATTTGGTAAAGTCTGCTGAAAT
TTTTGTAAAAATGCTTCAGGAAGGTGCAGTGAAAGAAAATATTGAAACATTGTATATGGATTTTACAGAAGCTGAAGCAG
TAAAACTTTTTGCTAATACCTATCTTGCCCTCCGGGTTTCCTATTTTAACGAGTTAGATACTTATTCTGAGATGAAAGGA
CTAGATACTCAAGCGATTATTGATGGAGTTTGTTTAGATCCGAGAATAGGTTCTCACTACAATAATCCTTCTTTTGGTTA
TGGGGGTTACTGTCTTCCTAAAGATACCAAGCAACTTCTTGCAAATTATTCTGACGTTCCACAAGAAATGATAACAGCTA
TAGTACAAAGTAATCGGACAAGAAAAGATTATATTGCAGATCGTATTTTAGATCTTGCTGGATCTTATGTAGGCAATGAT
TTCTATAAACCAGATAAAGAAAAAGAGATTGTTGTAGGAATTTATCGTTTAACAATGAAAAGTAATTCAGATAATTTTAG
ACAATCTTCTATTCAAGGTATTATGAAGCGTTTGAAAGCAAAAGGTGTTACTATTATTATTTACGAACCAACTCTTGAAA
GTGGTACTACTTTCTATGGTAGTCAAGTAGTTAATGATTTTGAAATATTTAAGAAATCTAGTCAAGTGATTGTTGCAAAT
CGTTTTGATGAGACTTTAGAAGATGTGAGGGGTAAAGTTTATACTAGGGATATTTTTAAGAGAGATTAA

Protein sequence :
MYNESVLRKEKIMKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSPIQDDYIEKYLAEKELNLVATLNAE
EAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIEAVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKA
LYDNLYPSRIIIGTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFNELDTYSEMKG
LDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQEMITAIVQSNRTRKDYIADRILDLAGSYVGND
FYKPDKEKEIVVGIYRLTMKSNSDNFRQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVAN
RFDETLEDVRGKVYTRDIFKRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 8e-81 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ugd YP_006742606.1 UDP-glucose 6-dehydrogenase VFG0963 Protein 3e-107 57