Gene Information

Name : wze (HMPREF1038_00399)
Accession : YP_006742599.1
Strain : Streptococcus pneumoniae gamPNI0373
Genome accession: NC_018630
Putative virulence/resistance : Virulence
Product : protein-tyrosine kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.10.-
Position : 347077 - 347742 bp
Length : 666 bp
Strand : +
Note : KEGG: saa:SAUSA300_0153 4.5e-33 cap5B; capsular polysaccharide biosynthesis protein Cap5B K00903; Psort location: CytoplasmicMembrane, score: 9.82

DNA sequence : 
ATGCCGACATTAGAAATAGCACAAAAAAAACTGGAGTTCATTAAGAAGGCAGAAGAATATTACAATACCTTGTGTACAAA
TATACAGTTGAGCGGAGATAAACTAAAAGTAATTTCCGTTACTTCTGTTAATCCGGGGGAAGGAAAAACAACTACTTCCG
TAAATATAGCAATGTCATTTGCGCGTGCAGGCTATAAAACTCTTTTGTTCGATGGCGATATTCGAAATTCAGTTATGTCA
GGATTTTTTAAATCTCGTGAAAAAATTACAGGGCTAACAGAATTTTTATCTGGGACAGCTGATTTATCTCACGGTTTATG
TGATACAAATATTGAAAATTTATTTGTAGTTCAATCGGGATCTGTATCACCAAACCCTACAGCCTTGTTACAAAGTAAAA
ATTTTAATGATATGATTGAAACATTGCGTAAATATTTTGATTATATCATTGTTGATACACCACCTATTGGAATTGTTATT
GATGCGGCAATTATCACTCAAAAGTGTGATGCGTCCATCTTGATAACAGCAACAGGTGAGGCGAATAAACGTGATGTCCA
AAAAGCGAAACAACAATTAGAACAAACAGGGAAACTGTTCCTGGGAGTTGTTTTAAATAAATTGGATATCTCGGTTGATA
AGTATGGAGTTTACGGTCGTAAATAG

Protein sequence : 
MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVNPGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMS
GFFKSREKITGLTEFLSGTADLSHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVYGRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cpsFD YP_006310771.1 putative autophosphorylating protein tyrosine kinase Not tested FWisland_4 Protein 7e-64 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wze YP_006742599.1 protein-tyrosine kinase VFG1368 Protein 7e-94 95
wze YP_006742599.1 protein-tyrosine kinase VFG1349 Protein 6e-58 57