Gene Information

Name : hlyB (B2904_orf614)
Accession : YP_006706710.1
Strain : Brachyspira pilosicoli B2904
Genome accession: NC_018607
Putative virulence/resistance : Virulence
Product : hemolysin B
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 605113 - 607617 bp
Length : 2505 bp
Strand : +
Note : -

DNA sequence :
ATGTCTTATCCATTTCGTCTTACTAATAAAGCTATAAGAATATTAGACTTACACTCTGTGGAAGAAGCTAAGAGATTAAA
TCATGATATGCTTACTCCAGAGCATGTTTTATTAGGAATATTTCATGAAACTGATTCAATAGTTGTGAATGTTTTAAATA
AATTAAAAATAGATATAGAAAAAATTAAATTTGATATAGAATCTTCTATGGTAAAATCTACAAGCAACACTAAATTGTTT
GGTAAGATACCTCCATCACCACGCATTCAGCATTTAATAAGCAGAGCGGCAGAAGAGGCTAAATCATTAGGAGATAATTG
CATAAGCACAGAACATTTACTTCTTGGTATTTTAAAAGAGGAAAATGGAATAGCATATAATGTACTTACTAGCTATAATT
TAGATTTAAAAACATTAAGACATGAGATGATGAGAATTAGAGGTAAATCTGGTTCTTCATCAAATATTTCTGAATCTTCT
TCTAGCACTATTCAAGAAGATAACACAGCAAGAACTCCTACTTTAGATAAGTTTGCACGTGATTTAACTAAAATGGCTAG
AGAAAAGGCTTTAGATAGAGTGATAGGCAGAGAAAACGAGGTAATGAGAGTTGTACAGATACTTTCAAGGAGAAAGAAAA
ATAACCCTATACTATTAGGAGAGCCTGGTGTTGGTAAGACTGCTATAGTTGAGGGGTTGGCTGAAAAGATTGTTTCTACT
GATGTGCCTGATATATTATTAAAAAAGAGAGTTTTGAGTTTAGATTTATCTTCTGTTGTTGCTGGTACTAAATATAGAGG
TGAGTTTGAAGAGAGAATAAAAAACATAGTAATGGAGATAAAGAAAGTTGGCAATATTATAATATTTATAGATGAGCTTC
ATACTTTAATTGGAGCAGGAGGAGCAGAGGGAGCTTTAGATGCTGCTAATATGCTTAAGCCTGCACTTTCACGCGGAGAG
ATTCAATGTATTGGTGCTACTACAATTAATGAATATAAAAAATATATAGAAAAAGATGGTGCTTTGGTGAGAAGATTTCA
GCCTATAAATGTTGAAGAGCCTTCTATTGAAGATACTATAGAAATATTAAATGGAATAAAATCTAAATATGAAGAGCATC
ATAAAGTAAAATATACTGATGGGGCTATTTATGCTTCTGCTGTATTAAGTAAAAGATATATATTTGAAAGACATTTACCA
GATAAGGCTATAGATTTAATTGATGAGGCAGGTTCGAGAGCAAGACTTATGAATATGGTAAGACCTCAGGAATTAAAAGA
TTTAGAAAATAAAATAAAAGAGCTTAATCAAGAAAAAGAGACTGTTGTAAAAAATCAGAATTTTGAAGAGGCTGTTAAAT
TAAGAGATGCTATAAAATCTTTACAAGAGGAATTGGATAAAAAAGAAGCTGAGTGGAGAAGCGAAAGAGACAAAACAGAA
ACAATTATTAATGAAGATGATATAAGACATGTAATATCAGAAATTACAAATATACCAGTAAAAAGATTATTAGATTCTGA
GAGTAAAAGACTTATTGGTATGGAAGATGAACTTCACAGTAAGATAGTAGGTCAGAAAGAAGCTATATCATCTATATCAA
AAGCTATAAGAAGAGCAAGAGCCGGATTAAAAAGTACTAAAAAACCGCTTGGAAGTTTTATATTTTTAGGTCCTACTGGT
GTTGGTAAAACTGCTTTAGCTAAAGTACTTTCAGAGTTTATGTTTGGAGATAGTGACGCTCTTATAAGAATAGATATGAG
TGAGTTTATGGAGAAGTTTGCAGTAAGCAGACTTATTGGAGCTCCTCCTGGATATGTTGGATATGAAGAGGGAGGCGGAC
TTACAGAGAAGGTAAGAAGAAAACCTTATTCTTTAATACTTTTTGATGAGATAGAAAAAGCTCACCCAGACATCACAAAC
ATACTTTTACAGGTGCTTGAAGAGGGGCAGCTTACAGATAACTTTGGAAGAAAGGTTGATTTCTCTAATACTATAATTAT
TATAACAAGCAACTTGGGTGCAAGAGATATTGTTAAAGGAACTTCTTTAGGTTTTAATGCCATTGGAAGTGAAAAAGATA
TTAATGACATGAAAAACTTTGCTATGGAAGAATTGAAGCAGAATTTCAATCCAGAGTTTTTAAACAGAATAGATGATATT
ATAGTATTCCATACTCTTACAAAAGAAGATTTGAAAGATATTATAGAGATTATGCTTAGAGAGTTGAATGAAGCTATAAA
AGATAGAAATATTTTTATAAGTTTAACTGATGATGCAAAAAATTATATAATAGATAAAGGCTTTGACAAGAAATATGGCG
CAAGAAGTTTAAGACGTGCTATACAAAAAGAGGTTGAAGATTATATTAGTACAGAGATACTTTTCGGGCATATTGAAGAG
GGCGATAATATAAATGTTGATTCTGATGGCCAGTCGCTGCTATTTAATGTTGAAAAGCTAAAGACCTACAGAGAAAATGA
GGTAGAAGAGTTATCTAAGAGTTGA

Protein sequence :
MSYPFRLTNKAIRILDLHSVEEAKRLNHDMLTPEHVLLGIFHETDSIVVNVLNKLKIDIEKIKFDIESSMVKSTSNTKLF
GKIPPSPRIQHLISRAAEEAKSLGDNCISTEHLLLGILKEENGIAYNVLTSYNLDLKTLRHEMMRIRGKSGSSSNISESS
SSTIQEDNTARTPTLDKFARDLTKMAREKALDRVIGRENEVMRVVQILSRRKKNNPILLGEPGVGKTAIVEGLAEKIVST
DVPDILLKKRVLSLDLSSVVAGTKYRGEFEERIKNIVMEIKKVGNIIIFIDELHTLIGAGGAEGALDAANMLKPALSRGE
IQCIGATTINEYKKYIEKDGALVRRFQPINVEEPSIEDTIEILNGIKSKYEEHHKVKYTDGAIYASAVLSKRYIFERHLP
DKAIDLIDEAGSRARLMNMVRPQELKDLENKIKELNQEKETVVKNQNFEEAVKLRDAIKSLQEELDKKEAEWRSERDKTE
TIINEDDIRHVISEITNIPVKRLLDSESKRLIGMEDELHSKIVGQKEAISSISKAIRRARAGLKSTKKPLGSFIFLGPTG
VGKTALAKVLSEFMFGDSDALIRIDMSEFMEKFAVSRLIGAPPGYVGYEEGGGLTEKVRRKPYSLILFDEIEKAHPDITN
ILLQVLEEGQLTDNFGRKVDFSNTIIIITSNLGARDIVKGTSLGFNAIGSEKDINDMKNFAMEELKQNFNPEFLNRIDDI
IVFHTLTKEDLKDIIEIMLRELNEAIKDRNIFISLTDDAKNYIIDKGFDKKYGARSLRRAIQKEVEDYISTEILFGHIEE
GDNINVDSDGQSLLFNVEKLKTYRENEVEELSKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlyB YP_006706710.1 hemolysin B VFG0079 Protein 0.0 51
hlyB YP_006706710.1 hemolysin B VFG0080 Protein 7e-143 51