Gene Information

Name : clpB (B2904_orf1734)
Accession : YP_006707813.1
Strain : Brachyspira pilosicoli B2904
Genome accession: NC_018607
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1791459 - 1794038 bp
Length : 2580 bp
Strand : +
Note : -

DNA sequence :
ATGGATTATAATAAATATACAATAAAAGCCCAAGAGGCAGTAAATGAAGCTGCTAATATAGCTAATGGTGAAGACCATAA
TGAAATAAAAAGCGAGCATTTACTTCTTGCATTATTAAAACAAGAGGACGGACTTATTCAGCCTTTAGTAGAAAGAATAG
GCGTTCCTATAAATACGTTAATAGATAAAACTCAAAGATTAGTTGATGAAAATGTAAAGGTTACAGGTGAAAATGTGCAG
TTACATTTATCTACTAATGCTGGTAAAGTTTTAGCAAAAGCAGAAAAAGAAGCTAATGCTTTAAAAGACCAATATGTATC
AACAGAGCATATATTCTTAGCACTTGTTGAAGCTGACAACAAAGCAGGCGATATGCTTAGAAAAAGCGGAATAAGTAAAA
AAGAAGTTTTAAGTGCATTAAAAGATTTAAGAAAAGGTCAAAGTGTAAATAGCCAAGACCCAGAAGCAAAAATGCAGGCA
CTTGATAAATACTGCCGTGATTTAACAGCATTAGCAGAAGCAGAAAAAATTGACCCTGTTATAGGACGTGATGAAGAGAT
AAGACGTGTTATGCAGGTCTTGTCAAGAAGAACTAAAAATAACCCTGTGCTTATAGGTGAGCCTGGTGTTGGTAAGACTG
CTATTGTTGAAGGACTTGCAAGAAGAATAGTTTCTCAAGATGTACCTGAAGGACTTAAAGATAAAAGGCTATTAGCTTTA
GATTTAGGTGCATTAGTAGCTGGTGCAAAATTCAGAGGAGAGTTTGAAGAGAGACTAAAAGCTGTTATCACAGAGATAGA
AAAATCTGAAGGAAGCATTATATTATTTATAGATGAGCTTCACACACTTGTAGGAGCTGGTGCTACAGAGGGAGCAATGG
ACGCTTCTAACCTTTTAAAACCTGCATTAGCAAGAGGCGAATTAAGAGCAATAGGTGCTACTACTTTAGATGAATATAGA
AAATATATTGAAAAAGATAAAGCACTTGAGAGAAGATTCCAACAAGTTTATTGTAAAGAGCCTAGTGTTGAAGATACTAT
TTCAATATTAAGAGGCTTAAAAGATAAATACGAAGTTCATCATGGTGTAAGAATAAAAGACGATGCATTAGTTGCTGCTG
CTGTTTTATCCAACAGGTATATAACTAACAGATTCTTACCAGACAAAGCTATTGACTTGGTAGATGAGGCTGCAAGCCAA
TTAAAAATAGAAATAGACAGTCAGCCTACTGAACTTGATAAAATTGAAAGAAAGATTTTACAGCTTAATATAGAAAAGCA
AGCTCTTTCAAAAGAAAATGATGCAGCATCTAAAGAGAGATTAGAAAAACTTGAAAAAGAATTATCTGAACTTTCAGAAG
AGCGTAATGCTATGAAACTTCAATGGGATAATGAAAAAGGAAGAATTGAAGAGACTAGAAAACTAAAAGAAGAACTTGAA
GCTTTAAATATAAAAGAGACTCAATATACAAGAGAAGGCAATTTAGCAAAGGCTGCTGAAATAAAATATGGTAAAATACC
AGAATTACAGAAAAAATTAGAAGAAGCTACTAAGGCTATGGAAGAAGCTAAAAACTCTGACAAGAAAGGTCTTTTAAGAG
AAGAGATTTCTGAAGATGATATAGCTAGAGTAATATCTGTATGGACTGGAATACCTGTAAGTAAAATGCTTACAAGTGAA
AAACAAAAATACTTACAGCTTGAAGAAGTATTACATAAAAGAGTTGTAGGACAAGATGAGGCTATAACTTCAGTTGCTGA
TGCCATAAGAAGAAACAGAGCAGGACTTTCTGATGAAAACAAACCGCTTGGAAGTTTCTTATTTATAGGACCTACTGGGG
TTGGTAAAACAGAGCTTGCTAAAACACTTGCTGATTTCTTGTTTAGCGATGAAAAAGCTTTAACAAGAATTGATATGAGT
GAATATATGGAGAAGTTTTCTGTTACTAGACTTATAGGAGCTCCTCCTGGATATGTAGGTTATGATGAGGGAGGACAATT
AACAGAAGCCGTTAGAAGAAGACCTTATTCTGTTATACTATTTGATGAGATAGAAAAAGCTCACCCTGATGTATTTAATG
TTTTACTTCAGGTATTAGATGATGGAAGGCTTACTGACGGACAAGGAAGAATAGTAGATTTCAAAAATGCTATTATCATA
ATGACAAGTAATTTGGGTTCTGACCTTATTCTTGAAGCTAATGATACTAATGATATCAAAGAAAAAATTCAAGAGTTACT
AAAAATATCATTTAGACCAGAGTTCTTAAACAGAATAGATGAGATAATAACATTTACTAGACTTGACAAAAAATACATTG
CTGAGATAGTAAGAAATCAAATAGCAAGAGTTGCTAACAGACTTAAAGATAGAAGAATAACTTTAGATGTAAGCGATGAA
GCTATAGACTATATTGCTGATATTGGTTATGACCCTCAGTTTGGAGCAAGACCATTAAAAAGAGCAATACAAAACTTTAT
AGAAAACCAACTAGCTAAAGAAATGTTAGCGGGCAAATATTTAGAAGGAGATACTATAAAAGTTATTAAATCAGGAGACG
GTTTGGTTTTTGAAAAATAA

Protein sequence :
MDYNKYTIKAQEAVNEAANIANGEDHNEIKSEHLLLALLKQEDGLIQPLVERIGVPINTLIDKTQRLVDENVKVTGENVQ
LHLSTNAGKVLAKAEKEANALKDQYVSTEHIFLALVEADNKAGDMLRKSGISKKEVLSALKDLRKGQSVNSQDPEAKMQA
LDKYCRDLTALAEAEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSQDVPEGLKDKRLLAL
DLGALVAGAKFRGEFEERLKAVITEIEKSEGSIILFIDELHTLVGAGATEGAMDASNLLKPALARGELRAIGATTLDEYR
KYIEKDKALERRFQQVYCKEPSVEDTISILRGLKDKYEVHHGVRIKDDALVAAAVLSNRYITNRFLPDKAIDLVDEAASQ
LKIEIDSQPTELDKIERKILQLNIEKQALSKENDAASKERLEKLEKELSELSEERNAMKLQWDNEKGRIEETRKLKEELE
ALNIKETQYTREGNLAKAAEIKYGKIPELQKKLEEATKAMEEAKNSDKKGLLREEISEDDIARVISVWTGIPVSKMLTSE
KQKYLQLEEVLHKRVVGQDEAITSVADAIRRNRAGLSDENKPLGSFLFIGPTGVGKTELAKTLADFLFSDEKALTRIDMS
EYMEKFSVTRLIGAPPGYVGYDEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRIVDFKNAIII
MTSNLGSDLILEANDTNDIKEKIQELLKISFRPEFLNRIDEIITFTRLDKKYIAEIVRNQIARVANRLKDRRITLDVSDE
AIDYIADIGYDPQFGARPLKRAIQNFIENQLAKEMLAGKYLEGDTIKVIKSGDGLVFEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-97 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_006707813.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2084 Protein 2e-105 43
clpB YP_006707813.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2076 Protein 1e-109 41