Gene Information

Name : hlyB (WESB_0643)
Accession : YP_006703201.1
Strain : Brachyspira pilosicoli WesB
Genome accession: NC_018604
Putative virulence/resistance : Virulence
Product : hemolysin B
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 686964 - 689468 bp
Length : 2505 bp
Strand : +
Note : -

DNA sequence :
ATGTCTTATCCATTTCGTCTTACTAATAAAGCTATAAGAATATTAGACTTACACTCTGTGGAAGAAGCTAAGAGATTAAA
TCATGATATGCTTACTCCAGAGCATGTTTTATTAGGAATATTTCATGAAACTGATTCAATAGTTGTGAATGTTTTAAATA
AATTAAAAATAGATATAGAAAAAATTAAATTTGATATAGAATCTTCTATGGTAAAATCTACAAGCAACACTAAATTGTTT
GGTAAGATACCTCCATCACCACGCATTCAGCATTTAATAAGCAGAGCGGCAGAAGAGGCTAAATCATTAGGAGATAATTG
TATAAGCACAGAACATTTACTTCTTGGTATTTTAAAAGAGGAAAATGGAATAGCATATAATGTACTTACTAGCTATAATT
TAGATTTAAAAACATTAAGACATGAGATGATGAGAATTAGAGGTAAATCTGGTTCTTCATCAAATATTTCTGAATCTTCT
TCTAGCACTATTCAAGAAGATAACACAGCAAGAACTCCTACTTTAGATAAGTTTGCACGTGATTTAACTAAAATGGCTAG
AGAAAAGGCTTTAGATAGAGTGATAGGCAGAGAAAACGAGGTAATGAGAGTTGTACAGATACTTTCAAGGAGAAAGAAAA
ATAACCCTATATTATTAGGAGAGCCTGGTGTTGGTAAGACTGCTATAGTTGAGGGGTTGGCTGAAAAGATTGTTTCTACT
GATGTGCCTGATATATTATTAAAAAAGAGAGTTTTGAGTTTAGATTTATCTTCTGTTGTTGCTGGTACTAAATATAGAGG
TGAGTTTGAAGAGAGAATAAAAAACATAGTAATGGAGATAAAGAAAGTTGGCAATATTATAATATTTATAGATGAGCTTC
ATACTTTAATTGGAGCAGGAGGAGCAGAGGGAGCTTTAGATGCTGCTAATATGCTTAAGCCTGCACTTTCACGCGGAGAG
ATTCAATGTATTGGTGCTACTACAATTAATGAATATAAAAAATATATAGAAAAAGATGGTGCTTTGGTGAGAAGATTTCA
GCCTATCAATGTTGAAGAGCCTTCTATTGAAGATACTATAGAAATATTAAATGGAATAAAATCTAAATATGAAGAGCATC
ATAAAGTAAAATATACTGATGGGGCTATTTATGCTTCTGCTGTATTAAGTAAAAGATATATATTTGAAAGACATTTACCA
GATAAGGCTATAGATTTAATTGATGAGGCAGGTTCGAGAGCAAGACTTATGAATATGGTAAGACCTCAGGAATTAAAAGA
TTTAGAAAATAAAATAAAAGAGCTTAATCAAGAAAAAGAGACTGTTGTAAAAAATCAGAATTTTGAAGAGGCTGTTAAAT
TAAGAGATGCTATAAAATCTTTACAAGAGGAATTGGATAAAAAAGAAGCTGAGTGGAGAAGCGAAAGAGACAAAACAGAA
ACAATTATTAATGAAGATGATATAAGACATGTAATATCAGAAATTACAAATATACCAGTAAAAAGATTATTAGATTCTGA
GAGTAAAAGACTTATTGGTATGGAAGATGAACTTCACAGTAAGATAGTAGGTCAGAAAGAGGCTATATCATCTATATCAA
AAGCTATAAGAAGGGCAAGAGCCGGATTAAAAAGCACTAAAAAACCGCTTGGAAGTTTTATATTTTTAGGTCCTACTGGT
GTTGGTAAAACTGCTTTAGCTAAAGTACTTTCAGAATTTATGTTTGGAGATAGTGATGCTCTTATAAGAATAGATATGAG
TGAGTTTATGGAGAAGTTTGCAGTAAGCAGACTTATTGGAGCTCCTCCTGGATATGTTGGATATGAAGAGGGAGGCGGAC
TTACAGAGAAGGTGAGAAGAAAACCTTATTCTTTAATACTTTTTGATGAGATAGAAAAAGCTCACCCTGACATCACAAAC
ATACTTTTACAGGTGCTTGAAGAGGGGCAGCTTACAGATAACTTTGGAAGAAAGGTTGATTTCTCTAATACTATAATTAT
TATAACAAGCAACTTGGGTGCAAGAGATATTGTTAAAGGAACTTCTTTAGGATTCAATGCCATTGGAAGTGAAAAAGATA
TTAATGACATGAAAAACTTTGCTATGGAAGAATTGAAGCAGAATTTCAATCCAGAGTTTTTAAACAGAATAGATGATATT
ATAGTATTCCATACTCTTACAAAAGAAGATTTGAAAGATATTATAGAGATTATGCTTAGAGAGTTGAATGAAGCTATAAA
AGATAGAAATATTTTTATAAGTTTAACTGATGATGCAAAAAATTATATAATAGATAAAGGCTTTGACAAGAAATATGGCG
CAAGAAGTTTAAGACGTGCTATACAAAAAGAGGTTGAAGATTATATTAGTACAGAGATACTTTTCGGGCATATTGAAGAG
GGCGATAATATAAATGTTGATTCTGATGGGCAGTCGCTGCTATTTAATGTTGAAAAGGTAAAGACCTACAGAGAAAATGA
GGTAGAAGAGTTATCTAAGAGTTGA

Protein sequence :
MSYPFRLTNKAIRILDLHSVEEAKRLNHDMLTPEHVLLGIFHETDSIVVNVLNKLKIDIEKIKFDIESSMVKSTSNTKLF
GKIPPSPRIQHLISRAAEEAKSLGDNCISTEHLLLGILKEENGIAYNVLTSYNLDLKTLRHEMMRIRGKSGSSSNISESS
SSTIQEDNTARTPTLDKFARDLTKMAREKALDRVIGRENEVMRVVQILSRRKKNNPILLGEPGVGKTAIVEGLAEKIVST
DVPDILLKKRVLSLDLSSVVAGTKYRGEFEERIKNIVMEIKKVGNIIIFIDELHTLIGAGGAEGALDAANMLKPALSRGE
IQCIGATTINEYKKYIEKDGALVRRFQPINVEEPSIEDTIEILNGIKSKYEEHHKVKYTDGAIYASAVLSKRYIFERHLP
DKAIDLIDEAGSRARLMNMVRPQELKDLENKIKELNQEKETVVKNQNFEEAVKLRDAIKSLQEELDKKEAEWRSERDKTE
TIINEDDIRHVISEITNIPVKRLLDSESKRLIGMEDELHSKIVGQKEAISSISKAIRRARAGLKSTKKPLGSFIFLGPTG
VGKTALAKVLSEFMFGDSDALIRIDMSEFMEKFAVSRLIGAPPGYVGYEEGGGLTEKVRRKPYSLILFDEIEKAHPDITN
ILLQVLEEGQLTDNFGRKVDFSNTIIIITSNLGARDIVKGTSLGFNAIGSEKDINDMKNFAMEELKQNFNPEFLNRIDDI
IVFHTLTKEDLKDIIEIMLRELNEAIKDRNIFISLTDDAKNYIIDKGFDKKYGARSLRRAIQKEVEDYISTEILFGHIEE
GDNINVDSDGQSLLFNVEKVKTYRENEVEELSKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlyB YP_006703201.1 hemolysin B VFG0079 Protein 0.0 51
hlyB YP_006703201.1 hemolysin B VFG0080 Protein 5e-143 51