Gene Information

Name : clpB (WESB_0993)
Accession : YP_006703550.1
Strain : Brachyspira pilosicoli WesB
Genome accession: NC_018604
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1075986 - 1078565 bp
Length : 2580 bp
Strand : -
Note : -

DNA sequence :
ATGGATTATAATAAATATACAATAAAAGCCCAAGAGGCAGTAAATGAAGCTGCTAATATAGCTAATGGTGAAGACCATAA
TGAAATAAAAAGCGAGCATTTACTTCTTGCATTATTAAAACAAGAGGACGGACTTATTCAGCCTTTAGTAGAAAGAATAG
GCATTCCTATAAATACGTTAATAGATAAAACTCAAAGATTAGTTGATGAAAATGTAAAGGTAACAGGAGAAAATGTGCAG
TTACATCTCTCTACTAATGCCGGTAAAGTTTTAGCAAAAGCAGAAAAAGAAGCTAATGCTTTAAAAGACCAATATGTATC
AACAGAGCATATATTCTTAGCACTTGTTGAAGCTGACAACAAAGCAGGCGACATGCTTAGAAAAAGCGGAATAAGTAAAA
AAGAAGTTTTAAGTGCATTAAAAGATTTAAGAAAAGGTCAAAGCGTAAATAGCCAAGACCCAGAAGCAAAAATGCAGGCA
CTTGATAAATACTGCCGTGATTTAACAGCATTAGCAGAAGCAGAAAAAATTGACCCTGTTATAGGACGTGATGAAGAGAT
AAGACGTGTTATGCAGGTATTGTCAAGAAGAACTAAAAATAACCCTGTGCTTATAGGTGAGCCTGGTGTTGGTAAGACTG
CTATTGTTGAAGGACTTGCAAGAAGAATAGTTTCTCAAGATGTACCTGAGGGACTTAAAGATAAAAGGCTATTAGCTTTA
GATTTAGGTGCATTAGTAGCTGGTGCAAAATTCAGAGGAGAGTTTGAAGAGAGATTAAAAGCTGTTATCACAGAGATAGA
AAAATCTGAAGGAAGCATTATATTATTTATAGATGAGCTTCACACACTTGTAGGAGCTGGTGCTACAGAGGGAGCAATGG
ACGCTTCTAACCTATTAAAACCTGCATTAGCAAGAGGCGAATTAAGAGCAATAGGTGCTACTACTTTAGATGAATATAGA
AAATATATTGAAAAAGATAAAGCACTTGAGAGAAGATTCCAACAGGTTTATTGTAAAGAGCCTAGTGTTGAAGATACTAT
TTCAATACTTAGAGGCCTAAAAGATAAATACGAAGTTCATCATGGTGTAAGGATAAAAGACGATGCATTAGTTGCTGCTG
CTGTTTTATCCAACAGGTATATAACTAACAGATTCTTACCAGACAAAGCTATTGACTTGGTAGATGAAGCTGCTAGCCAA
TTAAAAATAGAGATAGACAGTCAGCCTACTGAACTTGATAAAATAGAGAGAAAGATTTTACAGCTTAATATAGAAAAACA
AGCTCTTTCAAAAGAAAATGATGCAGCATCTAAAGAGAGATTAGAAAAACTTGAAAAAGAATTATCTGAACTTTCTGAAG
AGCGTAATGCTATGAAACTTCAATGGGATAATGAAAAAGGAAGAATTGAAGAGACTAGAAAATTAAAAGAAGAACTTGAA
GCTTTAAATATAAAAGAGACTCAATATACAAGAGAAGGTAATTTAGCAAAGGCTGCTGAAATAAAATATGGTAAAATACC
AGAACTTCAGAAAAAATTAGAAGAAGCAACTAAGGCTATGGAAGAAGCTAAAAACTCTGACAAGAAAGGTCTTTTAAGAG
AAGAGATTTCTGAAGATGATATAGCTAGAGTAATATCTGTATGGACTGGAATACCTGTAAGTAAAATGCTTACAAGCGAA
AAACAAAAATACTTACAGCTTGAAGAAGTGCTGCATAAAAGAGTTGTAGGACAAGATGAAGCTATCACTTCAGTTGCTGA
CGCAATAAGAAGAAACAGAGCAGGACTTTCTGATGAAAACAAACCTCTTGGAAGTTTCTTATTTATAGGACCTACTGGAG
TTGGTAAAACTGAGCTTGCTAAGACTCTTGCTGATTTCTTGTTTAGCGATGAAAAAGCTTTAACAAGAATTGATATGAGT
GAGTATATGGAGAAGTTTTCTGTTACTAGACTTATAGGAGCTCCTCCTGGATATGTAGGTTATGATGAAGGAGGACAATT
AACAGAAGCAGTTAGAAGAAGACCTTATTCTGTTATACTATTTGATGAGATAGAAAAAGCTCACCCTGATGTATTTAATG
TTTTACTTCAGGTGTTAGATGACGGAAGACTTACTGACGGACAAGGAAGAATAGTAGATTTCAAAAATGCTATTATCATA
ATGACAAGTAATTTGGGTTCTGACCTTATTCTTGAAGCTAATGATACTAATGATATCAAAGAAAAAATTCAAGAGTTACT
AAAAATGTCATTTAGACCAGAGTTCTTAAACAGAATAGATGAGATAATAACATTTACTAGACTTGACAAAAAATACATTG
CTGAGATAGTAAGAAATCAAATAGCAAGAGTTGCTAACAGACTTAAAGATAGAAGAATAACTTTAGATGTAAGCGATGAA
GCTATAGACTATATTGCTGATATTGGTTATGACCCTCAGTTTGGAGCAAGACCATTAAAAAGAGCAATACAGAATTATAT
AGAAAACCCACTAGCTAAAGAAATGTTAGCGGGCAAATATTTAGAAGGAGATACTATAAAAGTTATTAAATCAGGAGACG
GTTTGGTTTTTGAAAAATAA

Protein sequence :
MDYNKYTIKAQEAVNEAANIANGEDHNEIKSEHLLLALLKQEDGLIQPLVERIGIPINTLIDKTQRLVDENVKVTGENVQ
LHLSTNAGKVLAKAEKEANALKDQYVSTEHIFLALVEADNKAGDMLRKSGISKKEVLSALKDLRKGQSVNSQDPEAKMQA
LDKYCRDLTALAEAEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSQDVPEGLKDKRLLAL
DLGALVAGAKFRGEFEERLKAVITEIEKSEGSIILFIDELHTLVGAGATEGAMDASNLLKPALARGELRAIGATTLDEYR
KYIEKDKALERRFQQVYCKEPSVEDTISILRGLKDKYEVHHGVRIKDDALVAAAVLSNRYITNRFLPDKAIDLVDEAASQ
LKIEIDSQPTELDKIERKILQLNIEKQALSKENDAASKERLEKLEKELSELSEERNAMKLQWDNEKGRIEETRKLKEELE
ALNIKETQYTREGNLAKAAEIKYGKIPELQKKLEEATKAMEEAKNSDKKGLLREEISEDDIARVISVWTGIPVSKMLTSE
KQKYLQLEEVLHKRVVGQDEAITSVADAIRRNRAGLSDENKPLGSFLFIGPTGVGKTELAKTLADFLFSDEKALTRIDMS
EYMEKFSVTRLIGAPPGYVGYDEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRIVDFKNAIII
MTSNLGSDLILEANDTNDIKEKIQELLKMSFRPEFLNRIDEIITFTRLDKKYIAEIVRNQIARVANRLKDRRITLDVSDE
AIDYIADIGYDPQFGARPLKRAIQNYIENPLAKEMLAGKYLEGDTIKVIKSGDGLVFEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-98 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_006703550.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2084 Protein 2e-105 42
clpB YP_006703550.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2076 Protein 3e-109 41