Gene Information

Name : hly (LMOSLCC2376_0173)
Accession : YP_006689371.1
Strain : Listeria monocytogenes SLCC2376
Genome accession: NC_018590
Putative virulence/resistance : Virulence
Product : listeriolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 190962 - 192551 bp
Length : 1590 bp
Strand : +
Note : -

DNA sequence :
ATGAAAAAAATAATGCTAGTTTTTATTACACTTATATTAATTAGTCTACCAATAGCACAACAAACTGAAGCAAAGGACGC
ATCTGCATTCCATAAAGAAGATTTAATTTCATCCATGGCACCACCAGCATCTCCGCCTGCAAGTCCTAAGACGCCAATCG
AAAAGAAACACGCGGATGAAATCGATAAGTATATACAAGGATTGGATTACAATAAAAACAATGTATTAGTATACCACGGA
GATGCAGTGACAAATGTGCCGCCAAGAAAAGGTTACAAAGATGGAAATGAATATATCGTTGTGGAGAAAAAGAAGAAATC
CATCAATCAAAATAATGCAGACATCCAAGTTGTAAATGCAATTTCGAGCCTAACATATCCAGGTGCTCTCGTAAAAGCGA
ATTCGGAATTAGTAGAAAATCAACCAGATGTTCTCCCTGTAAAACGTGATTCATTAACACTTAGCATCGATTTGCCAGGA
ATGACTAATCAAGACAATAAAATCGTTGTAAAAAATGCTACTAAATCGAATGTTAACAACGCAGTAAATACATTAGTGGA
AAGATGGAATGAAAAATATGCTCAAGCTTATCCGAATGTAAGTGCAAAAATTGATTATGATGACGAAATGGCTTACAGTG
AATCACAATTAATTGCAAAATTTGGTACTGCATTTAAAGCTGTAAATAATAGTTTGAATGTAAACTTCGGCGCAATCAGT
GAAGGGAAAATGCAAGAAGAAGTCATTAGTTTTAAACAAATTTACTATAACGTGAATGTTAATGAACCTACAAGACCTTC
CAGATTTTTCGGCAAAGCTGTTACTAAAGAGCAGTTGCAAGCGCTTGGAGTAAATGCAGAAAATCCTCCTGCATATATCT
CAAGTGTGGCATACGGCCGTCAAGTTTATTTGAAATTATCGACTAATTCCCATAGTACTAAAGTAAAAGCTGCTTTTGAT
GCTGCCGTAAGTGGGAAATCTGTCTCAGGTGATGTAGAATTAACAAATATCATCAAAAATTCTTCCTTCAAAGCCGTAAT
TTACGGTGGTTCCGCAAAAGATGAAGTTCAAATCATCGATGGCAACCTCGGAGACTTACGAGATATTTTGAAAAAAGGTG
CTACTTTTAATCGAGAAACACCAGGAGTTCCCATTGCTTATACAACAAATTTCTTAAAAGACAATGAATTAGCTGTTATT
AAAAACAACTCAGAATATATTGAAACAACTTCAAAAGCTTATACAGATGGAAAAATTAATATTGATCACTCTGGAGGCTA
CGTTGCTCAATTCAACATCTCTTGGGATGAAATAAATTATGATCCTGAAGGTAACGAAATTGTTCAACATAAAAACTGGA
GCGAAAACAATAAAAGCAAGCTAGCTCATTTCACATCGTCCATCTATTTGCCAGGTAACGCAAGAAATATTAATGTTTAC
GCCAAAGAATGCACTGGTTTAGCTTGGGAATGGTGGAGAACGGTAATTGATGACCGGAACTTACCACTTGTGAAAAATAG
AAATATCTCCATCTGGGGCACTACGCTTTATCCGAAATATAGTAATAGTGTAGATAATCCAATCGAATAA

Protein sequence :
MKKIMLVFITLILISLPIAQQTEAKDASAFHKEDLISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHG
DAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPG
MTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAIS
EGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFD
AAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVI
KNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEINYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVY
AKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNSVDNPIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 0.0 99
slo YP_281505.1 streptolysin O Virulence Not named Protein 8e-99 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hly YP_006689371.1 listeriolysin O VFG0074 Protein 0.0 99
hly YP_006689371.1 listeriolysin O VFG1363 Protein 4e-107 44
hly YP_006689371.1 listeriolysin O VFG2275 Protein 3e-104 44
hly YP_006689371.1 listeriolysin O VFG0976 Protein 4e-99 43