Gene Information

Name : R0052_01545 (R0052_01545)
Accession : YP_006655125.1
Strain : Lactobacillus helveticus R0052
Genome accession: NC_018528
Putative virulence/resistance : Virulence
Product : ATP-dependent protease ATP-binding subunit ClpC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 282484 - 284964 bp
Length : 2481 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGAAAATTCATATAGTAAAAGCGTTAATCAAGTGTTAGAAATTGCGCGTGAACAAGCACAGGAGTTTCATCATCGGCT
AATTGGTACTGAGCATGTGTTATTGGCTATGGTGATTGAAACTGAAGGTGAAGCAGGAAAAATCTTGCGCTCATGGGGAT
TGACGCCAACTGCCGTACGAGAAGAGATTGAACGTTACACAGGCTATGGCTCAGCAGCTAAGTCAAGCTACATGGAAATG
TCACCTCGTTTAAGCTTAGCGTTAGATTATGCCAAAAGACAGGCTGACCAAGGTGGATATAAAGAAATTGAAACTAATCA
TGTTTTGCTAGGAATAACTGCTAGTGAACAGGTTTTGTCAGCCATGATTTTAAAGAACTTAAATGTTGATATTGGCCGTT
TGCGTCAAGATGTTAATGACAGCTTGGATCAAGAACAAGACTTTGGCGATTCAGCAAGCTGGTTAGGCAATAGCAATACC
GCTACTGGCCAAAAGAAACGTAAAAATAGTACTACACCAACTCTAGATAAAGTAGCGGTTAATTTAAATCAACGCACCCG
TGAAGGTGGAATTGATCCAGTTATTGGCCGTGAAAAAGAAATTAAGCGAGTTATTCAAATTTTATCTCGTCGTACTAAGA
ACAATCCAATTTTGGTAGGCGAATCTGGTGTAGGTAAAACTGCGGTCGCCGAAGCAATTGCTACAGAAATTGTTAATAAA
AAAGTTCCAGAAGGCTTGCTTGATAAGCGAGTAATGGCTCTTAACATGGGCAGTTTAGTAGCAGGCACTAAGTATCGTGG
TGAATTTGAAGATAGAATGAAAAAGATTTTGGATGAAATTGCCAAAGACGGTAAAGTCATTCTATTTGTCGATGAAATGC
ATACTTTGATTGGTGCTGGTGGTGCTGAAGGGGCAATTGATGCTTCTAATATTTTGAAACCTTCACTTGCGCGCGGCGAT
ATTCAAATGATTGGTGCTACTACATTTGATGAATATCAAAAGTACATTGAAAAGGATCAAGCATTGGCTCGTCGTTTCCA
ACAAGTACGTTTGAATGAACCTACTAAGAAGGATACGTTAGCTATTTTAAAGGGACTTAGACCTAAGTATGAAAAGTTCC
ACCATGTGACTATTTCAGATGCTAGTCTTGAGGATGCTGTTGATTTATCTAGTCGGTACATTACTAATCGGTTCTTGCCA
GATAAGGCGATTGATTTGGTAGATGAGGCTAGTGCAGCAGTTAAAATTAGAACTAATGTTGGTTCAAACAAAGATTTGGT
TCAAATTAATGAAAAGATAAAGAATATTATTGAACAAAAGAATGAAGCAGCTACGAGTCAGAACTTTGTTAAAGCAGCTC
AACTTCAAGAAGCACAAAACAATTTGCAAATGCAGCGAGAAGAAATGGAGAATGCATTGCAAGTTAAGGTTAGTGCTGAG
GCTGTTGTTGGCCCCGAAGATATTGCCAAGGTAGTATCTGACTGGACAGGTGTACCTGTTACTCAGATGAAGAGGGATGA
AAGTCGCCAATTAGCTAACTTAGAGAGCATTTTGCATAAACGCGTGATTGGGCAAGATAAGGCTGTTTCAGCTGTAGCTC
GTGCAATTCGTCGTAGCAGAAGCGGTATTAAGGATGAGCGCCGTCCAATTGGATCATTCTTGTTCTTAGGGCCAACAGGT
GTAGGTAAGACTGAATTAGCTAAATCAGTTGCAGCAGCAATGTTTGGGTCAGAAGATAATTTGATCAGATTAGATATGTC
TGAATACATGGATCAAATTGCCTCAAGCAAGTTAATTGGCTCAGCTCCTGGTTATGTTGGCTATGAAGAGGGCGGACAAC
TTTCTGAACAAGTTCGTCGTCATCCATATTCAGTTGTTTTGCTTGATGAAGTGGAAAAAGCTCATCCTGATGTATTTAAT
TTGCTTTTGCAAGTTTTGGATGAAGGATTTTTGACAGATTCTAAAGGCAGAAAAGTCGACTTTAGAAATACAATCATCAT
TATGACTTCTAATTTGGGTTCACGTACGTTATTTGACAGCAAGGCTGTAGGTTTCAATGCTGATAGGGTTGACCAAGCTA
AAGTAAGACAAGCTAAAGTTCAACAGGCAATTAAGCAATTCTTCCGTCCGGAATTTTTGAACCGAATTGATGAAACGATT
ATCTTTGATGAATTAACTAAGAAGCAGTTGCGGGACATTGTAACTTTACTTACTCACAAGTTGGTAGTTCGTTTGCAAAA
GAAGGGAATTACGCTTAGGATTTCCCGTGCCGCTTTGGATAAAATTGTTAAAGATGGTTATGACCCTGAAAATGGTGCTC
GTCCACTTAGAAGAGCAATCCAAAATGATATCGAAGATAAATTAGCAGAAATGTTGATTACAGGTGAAGTAAAAGCAAAC
GACACTTTGAAAATTGGTAGTCAACATGGTCATTTGAAATTTGATGTTGTGCCAGAGAAAAAACTGGTGAAAACTAAGTA
A

Protein sequence :
MENSYSKSVNQVLEIAREQAQEFHHRLIGTEHVLLAMVIETEGEAGKILRSWGLTPTAVREEIERYTGYGSAAKSSYMEM
SPRLSLALDYAKRQADQGGYKEIETNHVLLGITASEQVLSAMILKNLNVDIGRLRQDVNDSLDQEQDFGDSASWLGNSNT
ATGQKKRKNSTTPTLDKVAVNLNQRTREGGIDPVIGREKEIKRVIQILSRRTKNNPILVGESGVGKTAVAEAIATEIVNK
KVPEGLLDKRVMALNMGSLVAGTKYRGEFEDRMKKILDEIAKDGKVILFVDEMHTLIGAGGAEGAIDASNILKPSLARGD
IQMIGATTFDEYQKYIEKDQALARRFQQVRLNEPTKKDTLAILKGLRPKYEKFHHVTISDASLEDAVDLSSRYITNRFLP
DKAIDLVDEASAAVKIRTNVGSNKDLVQINEKIKNIIEQKNEAATSQNFVKAAQLQEAQNNLQMQREEMENALQVKVSAE
AVVGPEDIAKVVSDWTGVPVTQMKRDESRQLANLESILHKRVIGQDKAVSAVARAIRRSRSGIKDERRPIGSFLFLGPTG
VGKTELAKSVAAAMFGSEDNLIRLDMSEYMDQIASSKLIGSAPGYVGYEEGGQLSEQVRRHPYSVVLLDEVEKAHPDVFN
LLLQVLDEGFLTDSKGRKVDFRNTIIIMTSNLGSRTLFDSKAVGFNADRVDQAKVRQAKVQQAIKQFFRPEFLNRIDETI
IFDELTKKQLRDIVTLLTHKLVVRLQKKGITLRISRAALDKIVKDGYDPENGARPLRRAIQNDIEDKLAEMLITGEVKAN
DTLKIGSQHGHLKFDVVPEKKLVKTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-161 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
R0052_01545 YP_006655125.1 ATP-dependent protease ATP-binding subunit ClpC VFG0079 Protein 0.0 51
R0052_01545 YP_006655125.1 ATP-dependent protease ATP-binding subunit ClpC VFG0080 Protein 5e-133 49