Gene Information

Name : guaA (R0052_01385)
Accession : YP_006655097.1
Strain : Lactobacillus helveticus R0052
Genome accession: NC_018528
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 250427 - 251977 bp
Length : 1551 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
GTGGCTAAAAATCTAGACTATTTTGATAAAATTATTGTTCTTGACTTTGGTAGTCAATACAACCAATTGATTACTCGACG
CATTCGTGACTTCGGTATTTATTCAGAACTTTTACCTCACGATCTTTCTATTGCCAAGATTAAAGAAATGCATCCCAAGG
GCATTATTTTTTCTGGTGGTCCTAATAGTGTTTACGATGATGGTGCATTAAAAGTAGATCCAGAAATCTTCAAGTTGGGT
ATCCCAATTTTAGGTATTTGTTATGGAATGCAGCTCATGTCATATGACTTAGGCGGTAAGGTTGAACAGGCTGAGAACAA
AGAATATGGTCGTGCTAATATTACCGTTGAAGATCCTGATAGTGCATTGTTTAAGGGCCTGCCAAGTAAGCAATATGTTT
GGATGAGTCATGGTGATTTGGTAACTAAGGCTCCTAACGGCTTTGAGGTAACTGCTTCAAGCAAGAACTGTCCAATTGCT
GCTATTGCTAATCCAGATAAAAAGTTTTACGGTATTCAATTCCACGCAGAAGTACGTAATTCAGAATATGGTTTAGACAT
CTTGAAGCACTTTGCCTTTGATGTTTGTGGTGCTGAGACTAACTGGACCATGAACGACTTTATCGACATGAAGGTTGACG
ATATTCGTAAAGAAGTTGGTGACAAGAAGGTTATCTTAGGACTTTCAGGCGGTGTGGATTCCAGCGTTACTGCTACTCTT
TTACACAAAGCAATTGGCGATCAATTGACTGCAATTTTCGTTGATCACGGGATGCTGCGTAAAGATGAAGGCGACCAAGT
AATGCAAGCCTTGAATAAGGATCTTGGCGTCAACATTATTCGCGTTAACGCACAAAAGAGATTTTTGGACAAGTTAAAGG
GTGTTACTGATCCTGAACAAAAGCGTAAGATCATCGGTAAGGAATTTATCGAAGTCTTCAATGAAGAAGCTAAGAAGTTA
AAGGATGTAAACTTCTTAGCTCAAGGTACGCTTTATACTGATGTCATTGAATCAGGGACTAACACTGCCCAAACTATCAA
GTCTCACCACAACGTTGGTGGCCTTCCTAAGGACATGCACTTCAAGTTAATTGAACCCCTTCGTAAGTTGTTCAAGGATG
AAGTTCGTGAACTTGGTGAAAGATTAGGCATTCCACATGACTTAGTATGGCGTCAGCCATTCCCAGGTCCAGGTCTTGGT
ATTCGCGTGCTTGGCGAAGTTACAGAAGACAAGCTCAAGATTGTGCGTGATTCCGATGCGATTTTGCGTGAAGAAATCAA
GAAGGCTGGTTTGCAAGAAAAGATCTGGCAATACTTCACAGTTTTACCAGGTATTCGTTCAGTTGGCGTTATGGGTGACG
GCCGTACTTATGACTACACCATTGGTATTCGTGCCGTTACTTCAATTGATGGGATGACTGCTGATTTTGCCCAAATTCCA
TGGGATGTACTTGGTCATATTTCAGATAGAATCGTCAATGAAGTAGATAACGTTAACCGTGTAGTCTACGATGTGACGAG
TAAGCCACCTTCAACTATTGAATGGGAATAA

Protein sequence :
MAKNLDYFDKIIVLDFGSQYNQLITRRIRDFGIYSELLPHDLSIAKIKEMHPKGIIFSGGPNSVYDDGALKVDPEIFKLG
IPILGICYGMQLMSYDLGGKVEQAENKEYGRANITVEDPDSALFKGLPSKQYVWMSHGDLVTKAPNGFEVTASSKNCPIA
AIANPDKKFYGIQFHAEVRNSEYGLDILKHFAFDVCGAETNWTMNDFIDMKVDDIRKEVGDKKVILGLSGGVDSSVTATL
LHKAIGDQLTAIFVDHGMLRKDEGDQVMQALNKDLGVNIIRVNAQKRFLDKLKGVTDPEQKRKIIGKEFIEVFNEEAKKL
KDVNFLAQGTLYTDVIESGTNTAQTIKSHHNVGGLPKDMHFKLIEPLRKLFKDEVRELGERLGIPHDLVWRQPFPGPGLG
IRVLGEVTEDKLKIVRDSDAILREEIKKAGLQEKIWQYFTVLPGIRSVGVMGDGRTYDYTIGIRAVTSIDGMTADFAQIP
WDVLGHISDRIVNEVDNVNRVVYDVTSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-175 68
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-175 68
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-175 68
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-131 51