Gene Information

Name : R0052_11205 (R0052_11205)
Accession : YP_006656733.1
Strain : Lactobacillus helveticus R0052
Genome accession: NC_018528
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1984052 - 1985236 bp
Length : 1185 bp
Strand : +
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence : 
ATGGAATTTGATACAAAATTAATTCACGGTGGCATCAGCGAAGACAAATACACAGGCGCAACATCAGTCCCAATCTATAT
GGCATCCACCTTTCATCAACAGAAGATTGGTGAAAACGAATACGAATATTCCCGTTCGGGTAACCCCACCCGGGAAGCGG
TTGAAAAATTAATTGCCGATTTGGAAGACGGCACCGCTGGCTTTGCGTTTGCTTCCGGTTCGGCGGCCATCGATACGGTG
TTCTCACTATTTTCTGCCGGCGATCATTTCGTCATTGGCAATGACGTCTACGGTGGGACTTTCCGCTTGATTGACGCGGT
TTTAAAACGATTCGGCATGACGTTTACCGTCGTTGATACCCGCGACCTGCAAGCCGTTAAAGCCGCCATCACCCCCGCCA
CAAAGGCCATTTATTTGGAAACCCCGACCAATCCACTGCTGCGGGTAACCGATATCGCTGCCGTCGCTAAAATTGCTAAG
GACCGTGGTATTTTAAGCATTATCGACAACACTTTCTCATCGCCATACGTTCAACGGCCCTTAGACCTTGGCGTGGATAT
CGTTTTGCACAGTGCTTCTAAGTATCTTGGTGGCCATAGTGATCTGGTTGCCGGCCTGGTAGTCACTAAGGATCAAGCCC
TTGGCGAAAAAATTGGGTACCTGCAAAATGCCATCGGCGGCATCTTGGCACCCCAGGAGAGCTGGTTATTGCAACGGGGA
ATGAAGACCCTCTCACTTAGAATGCGGGCTCATTTGGCCAATGCGGAAGTAATCTTCAATTATTTGAAAAATCAGCCGCT
GGTCAGCAAAATTTACTATCCTGGCGATCCTAACAATCCGGATTACGAAGTTGCTCAGAAACAGATGCACGGATTTGGCG
CAATGATCTCGTTCGAATTACAAGCCGGTCTGGATCCCAAACAATTTGTCGAACAACTCCAAGTTATCACCCTGGCCGAA
AGTCTGGGCGCTCTTGAAAGTCTCATCGAAATTCCAGCCTTGATGACTCACGGTTCAATCCCCCGTGACATCCGGCTTAA
AAACGGCATCAAGGACGAACTAATCCGTCTGTCAGTCGGCGTTGAGGATCAAAAAGACCTATTAGCCGACCTGGAACGTG
GATTCGATAAACTAAAGGGGAGCCATCAAGATGTTTCAAACAGCAAGGTCCATTCTCAAGCGTGA

Protein sequence : 
MEFDTKLIHGGISEDKYTGATSVPIYMASTFHQQKIGENEYEYSRSGNPTREAVEKLIADLEDGTAGFAFASGSAAIDTV
FSLFSAGDHFVIGNDVYGGTFRLIDAVLKRFGMTFTVVDTRDLQAVKAAITPATKAIYLETPTNPLLRVTDIAAVAKIAK
DRGILSIIDNTFSSPYVQRPLDLGVDIVLHSASKYLGGHSDLVAGLVVTKDQALGEKIGYLQNAIGGILAPQESWLLQRG
MKTLSLRMRAHLANAEVIFNYLKNQPLVSKIYYPGDPNNPDYEVAQKQMHGFGAMISFELQAGLDPKQFVEQLQVITLAE
SLGALESLIEIPALMTHGSIPRDIRLKNGIKDELIRLSVGVEDQKDLLADLERGFDKLKGSHQDVSNSKVHSQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-87 52
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-88 52
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-67 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
R0052_11205 YP_006656733.1 cystathionine beta-lyase BAC0207 Protein 2e-66 45