Gene Information

Name : R0052_07990 (R0052_07990)
Accession : YP_006656175.1
Strain : Lactobacillus helveticus R0052
Genome accession: NC_018528
Putative virulence/resistance : Virulence
Product : alkaline phosphatase synthesis transcriptional regulatory protein phoP
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1402098 - 1402814 bp
Length : 717 bp
Strand : -
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
TTGAGAATCTTAATGGTTGAAGATGATAATTCCGTCGCTGAAATGATGGGAATGTTTTTCAAAAAAGAAGGTTGGCAGCA
AGATATCGCTGTCGACGGTGTCGAAGCCGTCGATATGTTTAAAGAAAATGCAGATAAGTATGATTTGATTACATTAGATT
TGAATTTGCCTAAAAAAGATGGTATTCAAGTTGCTAAGGAAGTAAGAGCTATTTCTCCTACTGTTCCGATTATTATGCTT
ACTGCTAGGGGCAGTGAATCAGATCAAGTTCTAGGATTAGGAATTGGTGCTGATGAGTATGTGACTAAGCCATTTAGTCC
AATCGCCTTAATTGCCCGTATCAAGGCACTTCATCGTCGCGTGATGATGGAAGAAGACGTTCAAACACAAGAAAATAATA
ATCAAGAATATGAAATTCAGACTGCTCATCTAAAGATTTCTAAGGATAGACGAGAAGTTTTATTTGATGACCAACCAGTT
GTTGATTTAACGCCGAAGGAATTTGATTTGTTATATACAATGGCGCAAAAGCCTAAGCAAGTCTTTTCGCGTGATCAATT
ATTAGAGCTGGTCTGGGGATATGAGTATTATGGTGAAGAACGAACTGTTGACGCCCATATTAAAAAATTGCGCCAAAAAC
TAGAAAAAGTTGGTGCCAAGGTTATCCAAACAGTCTGGGGCGTTGGCTATAAGTTTGACGATTCGCAGGTCAAATAA

Protein sequence : 
MRILMVEDDNSVAEMMGMFFKKEGWQQDIAVDGVEAVDMFKENADKYDLITLDLNLPKKDGIQVAKEVRAISPTVPIIML
TARGSESDQVLGLGIGADEYVTKPFSPIALIARIKALHRRVMMEEDVQTQENNNQEYEIQTAHLKISKDRREVLFDDQPV
VDLTPKEFDLLYTMAQKPKQVFSRDQLLELVWGYEYYGEERTVDAHIKKLRQKLEKVGAKVIQTVWGVGYKFDDSQVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 6e-35 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 6e-35 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_012469.1.7685629. Protein 1e-39 43
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP HE999704.1.gene2815. Protein 6e-41 43
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP CP001918.1.gene5135. Protein 1e-25 43
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_002952.2859905.p0 Protein 9e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_009641.5332272.p0 Protein 6e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_013450.8614421.p0 Protein 6e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_007793.3914279.p0 Protein 6e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_007622.3794472.p0 Protein 8e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_002745.1124361.p0 Protein 6e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_009782.5559369.p0 Protein 6e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_002951.3237708.p0 Protein 6e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_003923.1003749.p0 Protein 6e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP NC_002758.1121668.p0 Protein 6e-41 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP AE000516.2.gene3505. Protein 8e-36 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP AF155139.2.orf0.gene Protein 2e-41 41
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP FJ349556.1.orf0.gene Protein 2e-40 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP VFG1563 Protein 3e-35 42
R0052_07990 YP_006656175.1 alkaline phosphatase synthesis transcriptional regulatory protein phoP VFG1702 Protein 3e-35 42