Gene Information

Name : R0052_06780 (R0052_06780)
Accession : YP_006655969.1
Strain : Lactobacillus helveticus R0052
Genome accession: NC_018528
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1178496 - 1180265 bp
Length : 1770 bp
Strand : -
Note : COG0469 Pyruvate kinase

DNA sequence :
ATGAAGAAAACTAAGATTGTTAGTACTTTAGGACCAGCTTCAAACGATATTGAAACTATTACTGCTTTAGCTAAAGCTGG
TGCAAACGTATTCCGTTTCAACTTCTCACACGGTGATCACCCAGAACACCTTGCTCGTATGAAGATGGTTCGTCAAGTGG
AAAAGGATACTGGTATGCTTCTTGGCATCGACCTTGACACTAAGGGTGCTGAAATCAGAACCACTGAACAAGAAGGTGGT
AAGTTTACTATTAATACCGGTGATATGATCCGTGTATCAATGGACGACACCAAGAAGGGTAACAAGGACATGATCCACGT
TACCTACGAAGGTTTGTACGATGATACTCACGTTGGTGGTCACGTATTAATCGACGATGGTTTGGTTGACCTTTTGATTA
AGGAAAAGGATGACGCTAAGAGAGAATTAGTTTGTGAAGCTCAAAACACTGGTGTTATTGGCTCAAAGAAGGGTGTTAAC
GCTCCTGGTGTTGAAATCCGCCTTCCAGGTATCACTGAAAAGGATACTGACGACATTAAGTTCGGTTTACAATACGGTAT
TAACTTCATTACTGCTTCATTTGCACGTAAGGCTCAAGACATCTTAGACATTCGTAAGCTTTGTGAAGAAGCTGGCGCAG
ATTACGTTAAGATCTTCCCTAAGATTGAATCACAAGAAGGTATTGACAACGCTGACGAAATCTTACAAGTTTCAGATGGT
GTGATGGTAGCTCGTGGTGACATGGGTGTTGAAATTCCATTTATGGAAGTTCCATTTGTACAAAAGAGCTTAATCCGCAA
GGCTAACGCACTTGGTAAGCCAGTTATTACTGCTACTCAAATGCTTGACTCAATGCAAGAAAACCCACGTCCAACTCGTG
CCGAAGTTTCTGACGTTGCTAACGCTGTTCTTGATGGTACTGACGCAACTATGCTTTCAGGTGAATCAGCAAACGGTCTT
TACCCAGTTAAGGCTGTTAAGGCAATGGCTGAAATTGACGAACGTACTGAAAAAGAAATGCTTAAGCGTAACACTTTAGC
ACTTCAAAGATTCGAAGCTTACAAGGGTTCAAACGTAACTGAAGCTATCGGTGAATCAGTTGTACGTACTGCTCAAGAAT
TAGGTGTTAAGACTATCATTACTGCTACTAACTCAGGTTACACTGCACGTATGATTTCTAAGTACCGTCCAAACGCAGAC
ATCATTGCTTTGACTTTCGATGAAAAGATCCAACACTCATTGGGTATCGTTTGGGGTGTACAACCATTATTGACTGAAAA
GCCTAAGTCAACTGATGACATGTTTGAAGTAGCTGCTAAGGTAGCTAAGGAAAAGGGCTTTGTTAAGGATGGCGACCTTG
TAATCATCGTTGCTGGTGTTCCAGTTGGTGACTCAGGTACAACTAACTTGATGAGGTTACAAATTATCGGTAACAAGCTT
GTTCAAGGTTTAGGTGTTGGTAACGGTTCAGTTATCGGCAAGGCTGTTGTAGCAAACTCAGCTGAAGAAGCTAACAGCAA
GGTTAAGGAAGGCGACATCTTAGTTGCTAAGTCTACTGACCCAGACTACAACCCAGCTATCAAGAAGGCTTCAGGCTTAG
TTGTTGAAGCTTCAGGTTTGACTTCACACGCTGCAGTTATCGGTTTATCATTAGGTATCCCAGTTGTTGTTGGTACTACT
AACGCTACTGAAAAGATTTCTGATGGTTTAACTATTACTGTTGACGCTCGTCGTGGTGCTATCTACCAAGGCGAAATCTC
AAACCTTTAA

Protein sequence :
MKKTKIVSTLGPASNDIETITALAKAGANVFRFNFSHGDHPEHLARMKMVRQVEKDTGMLLGIDLDTKGAEIRTTEQEGG
KFTINTGDMIRVSMDDTKKGNKDMIHVTYEGLYDDTHVGGHVLIDDGLVDLLIKEKDDAKRELVCEAQNTGVIGSKKGVN
APGVEIRLPGITEKDTDDIKFGLQYGINFITASFARKAQDILDIRKLCEEAGADYVKIFPKIESQEGIDNADEILQVSDG
VMVARGDMGVEIPFMEVPFVQKSLIRKANALGKPVITATQMLDSMQENPRPTRAEVSDVANAVLDGTDATMLSGESANGL
YPVKAVKAMAEIDERTEKEMLKRNTLALQRFEAYKGSNVTEAIGESVVRTAQELGVKTIITATNSGYTARMISKYRPNAD
IIALTFDEKIQHSLGIVWGVQPLLTEKPKSTDDMFEVAAKVAKEKGFVKDGDLVIIVAGVPVGDSGTTNLMRLQIIGNKL
VQGLGVGNGSVIGKAVVANSAEEANSKVKEGDILVAKSTDPDYNPAIKKASGLVVEASGLTSHAAVIGLSLGIPVVVGTT
NATEKISDGLTITVDARRGAIYQGEISNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-78 47
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-78 47
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-78 47
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-78 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
R0052_06780 YP_006655969.1 pyruvate kinase VFG0479 Protein 1e-78 47