Gene Information

Name : B005_4271 (B005_4271)
Accession : YP_006643331.1
Strain : Nocardiopsis alba ATCC BAA-2165
Genome accession: NC_018524
Putative virulence/resistance : Virulence
Product : (2,3-dihydroxybenzoyl)adenylate synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 4487672 - 4489336 bp
Length : 1665 bp
Strand : +
Note : -

DNA sequence : 
ATGAACGACCGCCCCGGCCCCCGCGCCGTCGACCCCGCCGACTGGACCCCCTGGCCCCGCGAGTACGCCGACACCTATCG
GGCCGCCGGTCTCTGGACCGGCGAGACCTTCCCCGCCTTCCTGAGGGACCGCGCCGCCCGTTTCGGCGAGCGGACCGCCG
TCGTGGACGGCGACCTGCGCTGGACCTACGCCGAACTGGACCGGCGCGCCGACGCCCTGGCCGCCGGTCTGTCCCGCCTG
GGCGTGCGCGCGGGGGAGCGGGTCGTGGTGCACCTGCCCAACGTCGCGTCCCTGTTCGAGGTGGTGTTCGCGCTGTTCAG
GCTGGGCGCGCTGCCCGTCTACGCGCTGCCCGCCCATCGCCGCAGCGAACTGCTGCACCTGGCGGGCACCGCCGAGGCCG
TCGCCCTGATCACCACCGACCTCCAGGGCGCCTTCGACTGCCGACCCATGGCGGCGCGGGTCCGCGCGGAGGTCCCCTCG
CTGGAACACGTCGTCGTGGTGGGCGAGGCCGGTGACGAGGAGGGGTTCACCGCCCTGGAGGCGCTGCGCGCCGAACCCGA
CACCGCGATCCTCGCCGAACCCGACCCCGGATCGGTCGCCTTCTTCCAGCTCTCCGGCGGTACCACCGGGCTGCCCAAGC
TCATCCCCCGGACCCACGACGACTACCTGTACTCGGTGCGGGCCAGCGCCGACATCTGCGGCCTGGACACCGACACCGTC
TACCTGACCGCGTTGCCGGCCGTCCACAACTTCCCGATGAGCTCACCCGGGTTCCTCGGCGTGCTGCACGCGGGCGGCAC
CGTGGTCACCGCGCCCGACCCCTCCCCGGCGACCTGTCTGCCCCTGATCGAACGCGAGCACGTCACGCACACGGCGGTCG
TCCCGCCCGTGGCCATGCTGTGGATGGACGCGGTCGAACACGGCTCCCAGGGCGAACGCGACCTGTCCGACCTGCGCGTC
CTCCAGGTCGGCGGCGCCACCTTCCCACCGGAGGCGGCCCGCCGGGTCGCCCCGGTGCTGGGCTGCGCCCTCCAACAGGT
CTTCGGGATGGCCGAGGGGCTGGTCAACTACACCAGGGACGGCGACCCCGACGAGGTCGTCACCGGTACCCAGGGCCGCC
CGATCAGCGACCACGACGAGATCCTCATCGTCGACGACCGGGACCACCCGGTCCCCGACGGCGAACCCGGCCACCTGCTG
ACCCGGGGGCCCTACACGATCCGGGGCTACTACCGGGCGCCCGAGCACAACGCCGTCGCCTTCACCGATGACGGCTTCTA
CCGCACCGGCGACATCGTGCGCCGTCACCCCTCCGGCGCCCTCGTCGTCGCCGGACGCGCCAAGGACCAGATCAACCGGG
GCGGGGAGAAGATCGGCGCCGAGGAGATCGAGAACCACCTCCTGGCCCACCCGGCGGTCCACGACGCCTCCCTCGTCGCC
CTCCCCGACCCCTACCTGGGCGAACGCACCCACGCCTACGTCATCGCCCGGGGCGAGGCGCCCACACGGGGCGAACTGCT
CGCCTTCCTGCGCGAGCGGGGCCTGGCCGCCTACAAGATCCCCGACCGCGTCAGCTTCGTGGACGCCTTCCCGGCCACGG
CCGTCGGCAAGACCTCCAAGCGCGACCTGCGCGCGGCACGCACCACCTCCGGAACGGACCACTGA

Protein sequence : 
MNDRPGPRAVDPADWTPWPREYADTYRAAGLWTGETFPAFLRDRAARFGERTAVVDGDLRWTYAELDRRADALAAGLSRL
GVRAGERVVVHLPNVASLFEVVFALFRLGALPVYALPAHRRSELLHLAGTAEAVALITTDLQGAFDCRPMAARVRAEVPS
LEHVVVVGEAGDEEGFTALEALRAEPDTAILAEPDPGSVAFFQLSGGTTGLPKLIPRTHDDYLYSVRASADICGLDTDTV
YLTALPAVHNFPMSSPGFLGVLHAGGTVVTAPDPSPATCLPLIEREHVTHTAVVPPVAMLWMDAVEHGSQGERDLSDLRV
LQVGGATFPPEAARRVAPVLGCALQQVFGMAEGLVNYTRDGDPDEVVTGTQGRPISDHDEILIVDDRDHPVPDGEPGHLL
TRGPYTIRGYYRAPEHNAVAFTDDGFYRTGDIVRRHPSGALVVAGRAKDQINRGGEKIGAEEIENHLLAHPAVHDASLVA
LPDPYLGERTHAYVIARGEAPTRGELLAFLRERGLAAYKIPDRVSFVDAFPATAVGKTSKRDLRAARTTSGTDH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 9e-96 48
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-96 48
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-96 48
ybtE CAA21394.1 - Virulence HPI Protein 9e-96 48
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 6e-95 48
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-95 48
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-96 48
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-95 48
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-96 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
B005_4271 YP_006643331.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0168 Protein 8e-116 53
B005_4271 YP_006643331.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0932 Protein 2e-106 49
B005_4271 YP_006643331.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG1817 Protein 5e-101 49