Gene Information

Name : A79E_4459 (A79E_4459)
Accession : YP_006638219.1
Strain : Klebsiella pneumoniae 1084
Genome accession: NC_018522
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4730401 - 4732227 bp
Length : 1827 bp
Strand : +
Note : -

DNA sequence :
ATGCAACTTTACCTGTGCGAAAAACCCTCTCAGGCGCGCGATATCGCCCGTGTTCTTGACGCCCGTAACCGCAGCGACGG
CTACCTGCATAACGCCACCGTGACCATCACCTGGTGCTTCGGCCATCTGCTGAGCATGGCCGCGCCGGAGGATTACGATC
CGGCGCTGAAACACTGGCGGGCAGAGCATCTGCCGTTTATTCCCCCGGCATGGCGGCTGGTGATCCGCCCGGAGGTGCGC
AAGCAGTTCCGTATCATCGAAAAGCTGCTGAAACAGGCGGATGCAGTGGTGATTGCCACCGATGCCGACCGCGAAGGCGA
AACCATCGCCCGTGAAATTCTGGAGCAATGTCGCTGGCGCGGTCCGGTCCAGCGGCTGTGGCTGTCGGCACTGGATGACG
CCAGTATCCACAAGGCGCTTGCTGCGATGCGATCCGGTGACAGTACGTATCCGCTGTATCAGGCTGGACTGGCGCGCGCC
CGCGCCGACTGGCTGGTCGGCATCAACATGACCCGCGCCTGCACGCTGATGAACCGGCGGCACAAAGGCGTGCTCTCCGT
GGGCCGGGTGCAGACGCCGACCTTACGCCTGGTGGTGGAACGCGACCGGGAGATATCCCGCTTCACGCCCCGCCCCTGGT
GGCGGGTGGACGCCCGGTTGCATGCTGAGGGCACTACCTTTCTGGCGCAGTGGCAACCCGATGGGGTGTACTGTGACGAC
GAAGGCCGCTGTATCCGTGAATCCGCCGCCCGTGAGGCCACTGCGAGCCTGCAACAGGCCGGGACCACGCTGGTACTGGA
TGTGACCACCCGGCGGGAGAAAACGCCGCCACCGCTGGCCTTCACCCTCAGCGCCCTGCAGCAGGTCTGCTCAAAACAGT
GGGGCATGGGCGCGCAGGAGGTACTGGATATCGCCCAGCGCCTGTATGAAACCCATAAGGCCACCACCTATCCGCGCACC
GACTGCGGCTGGCTGCCGCTCTCCATGCACACTGAAGCACCGCAGGTTCTGGCGGCGCTGGTCGCCAGCGACATCTCACT
GCAGCCCCTCGCCACGCAACTGAATTTGCAACAACACTCCCGGCTATGGGACGACAGCAAAATCACCGCCCACCATGGCA
TCATCCCGACCCGTAAAACGGTAGATCTGACGCAGATGAATGACAGCGAGCGCAAGGTTTACGGCCTGGTACGCAGCCAT
TTTCTGGCGCAGTTTCTGTCGGACCATGAGGTGGATAAAACCGACCTGCGCCTGAACTGCGCTGGGGAAACGCTGGCTGC
CCGAGGCTCAGTCGTGATTGTCAGCGGCTGGCAACAACTGTTTTTACGCGAGATGGCAACACATTCACCGGAAGAAACGC
AGTCACTTCCCGTCCTGCAACAGGGACAAACCTGCCAGGTGGAACAGGTAGACGTTCGCGCCCGTCAGACTCAACCGCCG
GAGCACTACACCGAAGGGACGCTGATTGCCGCGATGAAAAACGCCGCCCGTTTTGTCAGCGATGAGCGCTTGAAACAGCG
GCTGAAAGAGAACGCCGGTATTGGCACCGAAGCCACCCGCGCCGGGATTATCCAGACGCTGCTTAAGCGTGGTTATCTGA
TTAAGCAACGCCGCTTTCTGTTGGCAACGGATACCGCCAGCGCGCTGATTGACGCCCTGCCGGAAAAGCTGAAAGATCCG
GGCACCACTGCACTGTGGGAGCAGATGCTGGATGACATCGCGACGGGGAAAATGGGGCTGGAGGCGTTCCTGGTGCAGCA
GCAAGAAACCGTTACAGCGCTCACGGCTCAAATAGTCAGAGGCCAGAAAAGTGGCTCATCAGGTTAG

Protein sequence :
MQLYLCEKPSQARDIARVLDARNRSDGYLHNATVTITWCFGHLLSMAAPEDYDPALKHWRAEHLPFIPPAWRLVIRPEVR
KQFRIIEKLLKQADAVVIATDADREGETIAREILEQCRWRGPVQRLWLSALDDASIHKALAAMRSGDSTYPLYQAGLARA
RADWLVGINMTRACTLMNRRHKGVLSVGRVQTPTLRLVVERDREISRFTPRPWWRVDARLHAEGTTFLAQWQPDGVYCDD
EGRCIRESAAREATASLQQAGTTLVLDVTTRREKTPPPLAFTLSALQQVCSKQWGMGAQEVLDIAQRLYETHKATTYPRT
DCGWLPLSMHTEAPQVLAALVASDISLQPLATQLNLQQHSRLWDDSKITAHHGIIPTRKTVDLTQMNDSERKVYGLVRSH
FLAQFLSDHEVDKTDLRLNCAGETLAARGSVVIVSGWQQLFLREMATHSPEETQSLPVLQQGQTCQVEQVDVRARQTQPP
EHYTEGTLIAAMKNAARFVSDERLKQRLKENAGIGTEATRAGIIQTLLKRGYLIKQRRFLLATDTASALIDALPEKLKDP
GTTALWEQMLDDIATGKMGLEAFLVQQQETVTALTAQIVRGQKSGSSG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 5e-160 53
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 7e-160 53
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 7e-160 53
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 3e-151 53
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 2e-155 53
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-153 53
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 8e-150 52
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 4e-159 51