Gene Information

Name : mccB (B657_27250)
Accession : YP_006630821.1
Strain : Bacillus subtilis QB928
Genome accession: NC_018520
Putative virulence/resistance : Resistance
Product : bifunctional cystathionine gamma-lyase/homocysteinegamma-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.1
Position : 2716440 - 2717579 bp
Length : 1140 bp
Strand : -
Note : -

DNA sequence :
ATGAAGAAAAAAACATTGATGATACATGGCGGAATCACAGGTGATGAGAAAACAGGCGCAGTTTCCGTGCCGATTTATCA
AGTAAGCACGTACAAGCAGCCGAAAGCAGGGCAGCATACAGGCTACGAGTATTCAAGAACGGCCAATCCGACTCGAACCG
CTCTCGAAGCACTTGTGACAGAACTGGAAAGCGGGGAAGCAGGCTATGCGTTCAGCTCAGGAATGGCTGCCATTACAGCG
GTTATGATGCTGTTTAACAGCGGAGATCATGTCGTGTTGACTGATGATGTGTACGGCGGAACATATCGCGTGATGACAAA
GGTGCTTAACCGTCTTGGCATTGAATCAACATTTGTTGATACGAGCAGCAGGGAAGAAGTTGAAAAAGCGATTCGCCCTA
ATACAAAAGCAATTTATATTGAAACACCGACAAACCCGTTGCTCAAAATCACCGACCTGACGCTCATGGCTGATATCGCA
AAAAAAGCGGGTGTTCTGCTTATCGTAGACAATACCTTTAATACTCCTTATTTTCAACAGCCGCTTACTTTAGGCGCTGA
TATCGTACTGCACAGTGCGACAAAATATCTTGGCGGACACAGTGATGTCGTCGGAGGTTTAGTTGTGACAGCTTCGAAAG
AGCTTGGAGAAGAGCTGCATTTTGTGCAAAACTCCACAGGCGGCGTGCTCGGCCCTCAAGATTCCTGGCTGTTAATGAGA
GGAATCAAAACGTTGGGACTCAGAATGGAAGCGATCGATCAAAATGCGCGGAAAATCGCAAGCTTTCTTGAGAATCACCC
TGCTGTCCAAACGTTATATTACCCTGGTTCTTCAAATCATCCCGGACATGAGCTTGCAAAAACGCAAGGAGCGGGCTTCG
GCGGCATGATCTCCTTTGATATTGGCAGTGAAGAACGGGTTGATGCGTTTTTAGGAAATCTGAAACTGTTTACCATTGCT
GAAAGCCTGGGGGCGGTTGAAAGCTTAATTTCTGTTCCTGCAAGAATGACACATGCCTCTATTCCGAGAGAACGCCGGCT
TGAGCTCGGCATTACGGACGGCTTGATCAGAATTTCTGTAGGAATTGAAGATGCGGAAGACTTGTTGGAAGATATCGGCC
AAGCGCTTGAAAATATATAA

Protein sequence :
MKKKTLMIHGGITGDEKTGAVSVPIYQVSTYKQPKAGQHTGYEYSRTANPTRTALEALVTELESGEAGYAFSSGMAAITA
VMMLFNSGDHVVLTDDVYGGTYRVMTKVLNRLGIESTFVDTSSREEVEKAIRPNTKAIYIETPTNPLLKITDLTLMADIA
KKAGVLLIVDNTFNTPYFQQPLTLGADIVLHSATKYLGGHSDVVGGLVVTASKELGEELHFVQNSTGGVLGPQDSWLLMR
GIKTLGLRMEAIDQNARKIASFLENHPAVQTLYYPGSSNHPGHELAKTQGAGFGGMISFDIGSEERVDAFLGNLKLFTIA
ESLGAVESLISVPARMTHASIPRERRLELGITDGLIRISVGIEDAEDLLEDIGQALENI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-109 59
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-107 58
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-77 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mccB YP_006630821.1 bifunctional cystathionine gamma-lyase/homocysteinegamma-lyase BAC0207 Protein 1e-68 44