Gene Information

Name : aadK (B657_26790)
Accession : YP_006630775.1
Strain : Bacillus subtilis QB928
Genome accession: NC_018520
Putative virulence/resistance : Resistance
Product : aminoglycoside 6-adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.-
Position : 2667121 - 2667975 bp
Length : 855 bp
Strand : -
Note : -

DNA sequence :
ATGCGAAGTGAGCAGGAAATGATGGACATTTTTTTGGACTTTGCTTTGAACGATGAGAGAATCCGATTGGTCACTTTGGA
AGGGTCACGTACAAACAGAAATATCCCTCCTGACAACTTCCAAGATTATGACATCTCGTATTTTGTAACTGATGTAGAAT
CTTTTAAAGAAAATGATCAGTGGCTCGAAATCTTTGGGAAGCGCATTATGATGCAAAAACCAGAAGATATGGAGCTTTTT
CCTCCCGAATTAGGTAATTGGTTTTCATACATTATTCTTTTTGAGGATGGCAACAAATTAGATCTAACCCTTATTCCAAT
TCGTGAAGCAGAAGATTATTTTGCTAATAACGATGGTTTGGTTAAGGTATTGCTTGATAAGGATTCGTTCATCAACTATA
AAGTGACCCCAAATGATCGCCAATACTGGATAAAAAGGCCGACTGCAAGGGAATTTGATGATTGCTGTAATGAGTTCTGG
ATGGTTTCGACTTACGTAGTAAAAGGACTAGCAAGAAATGAAATCCTTTTTGCCATTGACCATTTAAATGAAATTGTACG
TCCTAATTTATTGAGAATGATGGCCTGGCATATCGCATCTCAGAAAGGGTATTCATTTAGTATGGGGAAGAACTATAAAT
TTATGAAGCGGTACCTTTCAAATAAAGAATGGGAGGAACTCATGTCTACATATTCTGTGAATGGGTATCAGGAAATGTGG
AAGTCTTTATTTACTTGCTATGCATTATTTAGAAAGTATTCAAAAGCTGTATCAGAAGGTCTTGCATATAAGTATCCTGA
TTACGATGAAGGTATTACTAAGTATACGGAAGGTATTTATTGCTCAGTAAAGTGA

Protein sequence :
MRSEQEMMDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQWLEIFGKRIMMQKPEDMELF
PPELGNWFSYIILFEDGNKLDLTLIPIREAEDYFANNDGLVKVLLDKDSFINYKVTPNDRQYWIKRPTAREFDDCCNEFW
MVSTYVVKGLARNEILFAIDHLNEIVRPNLLRMMAWHIASQKGYSFSMGKNYKFMKRYLSNKEWEELMSTYSVNGYQEMW
KSLFTCYALFRKYSKAVSEGLAYKYPDYDEGITKYTEGIYCSVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 1e-81 60
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 5e-81 58
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 5e-81 58
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 9e-76 58
aadE AFJ97257.1 streptomycin aminoglycoside 6-adenyltransferase Not tested Not named Protein 2e-56 55
SAKOR_00397 YP_008490581.1 Aminoglycoside 6-adenylyltransferase Not tested vSa¥á Protein 3e-45 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadK YP_006630775.1 aminoglycoside 6-adenylyltransferase FN594949.1.gene25.p0 Protein 2e-76 58
aadK YP_006630775.1 aminoglycoside 6-adenylyltransferase NC_006663.1.orf0.gen Protein 2e-74 58
aadK YP_006630775.1 aminoglycoside 6-adenylyltransferase AJ489618.1.orf2.gene Protein 2e-57 56