Gene Information

Name : Desmer_3913 (Desmer_3913)
Accession : YP_006623620.1
Strain : Desulfosporosinus meridiei DSM 13257
Genome accession: NC_018515
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.15
Position : 4074131 - 4075432 bp
Length : 1302 bp
Strand : -
Note : PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; flagellar protein export ATPase FliI

DNA sequence :
ATGGGGGCGTGGAATCTGTTAGCTGAGACTGTGGATCGCTTAGAGCCGTTCTCTGCTCAAGGCAGGGTCTCCAAAATTGT
CGGTTTGATGGTAGAATCAGCGGGTCCTCGGGCTAGTGTGGGAGAATATTGCCATATTATTACCCGAGGCGGCCTGGAAC
TTCCGGCTGAAGTAGTAGGTTTTCGAGATTCGACAACACTGTTGATGCCCCTGGGAGAGCTTGAAGGAATTGCTCCCGGA
GACCGTGTTCTTTCTCAACGGCAAAAGTTGACCGTGTCTGTGGGTCCCGGCCTTCTCGGTCGGATTTTTGATGGCTTGGG
ACATCCTCTGGATGGTCGCCCGCTTCAGACGATAACAGCATACCCGCTGCAGAATAAACCACCAAGTGCTATCCTGCGTC
CTCGAATTCAAGACCCATTAAGTGTTGGGGTTAGAACGATTGACGGAATCCTGACAATCGGCCGAGGGCAGAGGATGGGT
ATTTTCGCCGGGTCAGGTGTAGGGAAAAGTACTCTGCTGGGGATGATGGCTAGAAATACTGTTGCGGATATCAATGTTAT
TGCCCTGATCGGCGAGCGAGGTCGAGAATTACGAGATTTTATTGAGAAGGATTTAGGTCCGGAAGGCTTAGCCCGATCTG
TAATTATTGTAGCTACATCAGATCAGCCAGCCTTAGTGCGTTTAAAGGCAGCCCTAACTGCTACTGCTGTTGCAGAGTAT
TTCAGGGATCAAGGAAAAAACGTTCTCCTGATGATGGACTCGGTGACTCGATTTGCTATGGCTCAACGGGAAGTAGGCCT
GACGGTGGGAGAACCCCCGGCGACTCGCGGATACCCACCTTCTGTCTTTGCACTTTTGCCAAAGCTGCTGGAAAGGGCGG
GCATGGCGGAGGTAGGAAGTATCACCGGGATTTACACGGTGCTAGTGGATGGAGATGACCATAATGAGCCTATCGCCGAC
TCGGTGCGAGGTATTCTGGATGGACATATTGTTCTAACGAGAGAATTAGCTATGCAGAACATGTTTCCGGCAATTGACAT
TTTGCAATCCGTTAGTCGGGTTATGAATGATGTTGTCAGCCCTGACCAAAAAACTTTAGCCGGACAGGTTCGTGAATATA
TCGCTATCTATCGTGATGCTAAGGATTTAATTGACATTGGGGCATATACTCCGGGAAGTAATCCTAAGATTGATGCAGCC
ATTGCTCATATGGATCGTATTCAAGGTTTTTCACGGCAAATGGTCGACGAATATGTTACCTATCCAGAGATGCTTAAACA
ATTGCAAGGGATTTTTAGTTAG

Protein sequence :
MGAWNLLAETVDRLEPFSAQGRVSKIVGLMVESAGPRASVGEYCHIITRGGLELPAEVVGFRDSTTLLMPLGELEGIAPG
DRVLSQRQKLTVSVGPGLLGRIFDGLGHPLDGRPLQTITAYPLQNKPPSAILRPRIQDPLSVGVRTIDGILTIGRGQRMG
IFAGSGVGKSTLLGMMARNTVADINVIALIGERGRELRDFIEKDLGPEGLARSVIIVATSDQPALVRLKAALTATAVAEY
FRDQGKNVLLMMDSVTRFAMAQREVGLTVGEPPATRGYPPSVFALLPKLLERAGMAEVGSITGIYTVLVDGDDHNEPIAD
SVRGILDGHIVLTRELAMQNMFPAIDILQSVSRVMNDVVSPDQKTLAGQVREYIAIYRDAKDLIDIGAYTPGSNPKIDAA
IAHMDRIQGFSRQMVDEYVTYPEMLKQLQGIFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-103 54
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-103 54
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-102 53
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-102 53
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-102 53
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-101 52
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 5e-102 52
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 5e-102 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-101 52
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-102 52
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-85 50
escN AAL57542.1 EscN Virulence LEE Protein 8e-90 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 8e-90 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 8e-90 49
escN AAC31513.1 L0034 Virulence LEE Protein 6e-90 49
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 5e-90 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 6e-90 49
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-90 49
escN CAC81862.1 EscN protein Virulence LEE II Protein 4e-90 49
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-90 49
escN AAC38383.1 EscN Virulence LEE Protein 1e-90 49
escN AAK26715.1 EscN Virulence LEE Protein 8e-90 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-90 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-90 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 6e-90 49
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-87 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 6e-88 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-87 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-88 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-86 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-86 47
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-84 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 8e-85 47
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-85 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-84 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-75 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-88 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-75 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-78 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-79 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-79 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-67 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 4e-74 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 4e-74 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-67 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-67 41
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-67 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 9e-107 54
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 5e-102 52
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 5e-101 52
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 9e-107 51
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 3e-89 50
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 9e-98 50
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 3e-90 49
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 8e-91 49
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 1e-93 49
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 3e-88 48
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 2e-72 43
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG1008 Protein 2e-68 42
Desmer_3913 YP_006623620.1 type III secretion system ATPase, FliI/YscN VFG0555 Protein 5e-68 41