Gene Information

Name : BCK_12275 (BCK_12275)
Accession : YP_006596556.1
Strain : Bacillus cereus FRI-35
Genome accession: NC_018491
Putative virulence/resistance : Resistance
Product : DNA-binding response regulator PhoP
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2446916 - 2447635 bp
Length : 720 bp
Strand : +
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence :
ATGAACAATCGTATTTTAGTAGTTGATGATGAGGAGTTTATCTTAACTTTAATCGAATTTAATTTACAACAAGCTGGTTT
TGAAGTGATAACAGCGATGGATGGAGAAATGGCGCTTCAAAAAGCGACAACAGAACGTCCAGATTTAATTATATTAGATT
TAATGCTTCCAAAAATGGATGGTATGGAAGTATGTAAAGAATTACGATTGCAGCGCGTTATGACACCGATTTTAATGTTA
ACAGCAAAAGATGATGAATTTGATAAGGTGCTAGGTCTTGAACTTGGGGCTGATGATTATATGACGAAGCCATTTAGTCC
AAGGGAAGTTGTCGCGCGTGTGAAGGCAATTTTACGCCGTACGAAATTACAACAAGAAGAGCAAGTTACAGAATCATCAG
ATGAAGAGAGCATTACAATTGCTGAACTTAAAATTTTACCAGAGTTTTATGAGGCTTATTTCCAAGGAAGAAAGCTTGAA
TTAACACCAAAAGAATTTGAACTACTTGTTTATCTTGCGAAAAATAAAAGTCGCGTATTAACGCGTGATCAATTATTAAG
TGCTGTATGGAATTATGATTTCGCTGGTGATACACGAATTGTTGACGTTCATATTAGCCATTTGCGCGATAAAATTGAAC
AAAATACGAAAAAACCGACGTACATTAAAACGATACGTGGTTTAGGATATAAATTAGAGGAGCCAAAAGGGGATGAATAA

Protein sequence :
MNNRILVVDDEEFILTLIEFNLQQAGFEVITAMDGEMALQKATTERPDLIILDLMLPKMDGMEVCKELRLQRVMTPILML
TAKDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRRTKLQQEEQVTESSDEESITIAELKILPEFYEAYFQGRKLE
LTPKEFELLVYLAKNKSRVLTRDQLLSAVWNYDFAGDTRIVDVHISHLRDKIEQNTKKPTYIKTIRGLGYKLEEPKGDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 3e-34 41
vanRB NP_815956.1 DNA-binding response regulator VanRB Not tested Not named Protein 2e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP HE999704.1.gene2815. Protein 4e-73 66
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_009782.5559369.p0 Protein 6e-75 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_002951.3237708.p0 Protein 6e-75 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_007622.3794472.p0 Protein 7e-75 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_002758.1121668.p0 Protein 6e-75 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_009641.5332272.p0 Protein 6e-75 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_013450.8614421.p0 Protein 6e-75 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_002952.2859905.p0 Protein 1e-74 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_007793.3914279.p0 Protein 6e-75 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_003923.1003749.p0 Protein 6e-75 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_002745.1124361.p0 Protein 6e-75 63
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_012469.1.7686381. Protein 1e-62 56
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP AE016830.1.gene1681. Protein 7e-64 55
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_012469.1.7685629. Protein 4e-54 53
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP BAC0197 Protein 1e-28 44
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP AE000516.2.gene3505. Protein 4e-41 44
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP001918.1.gene5135. Protein 9e-32 44
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP001485.1.gene721.p Protein 5e-36 43
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP004022.1.gene3215. Protein 2e-36 43
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP BAC0533 Protein 2e-34 43
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP000647.1.gene4257. Protein 2e-34 43
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP AF155139.2.orf0.gene Protein 3e-38 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP FJ349556.1.orf0.gene Protein 1e-39 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP000034.1.gene3834. Protein 2e-33 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP001138.1.gene4273. Protein 7e-34 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_002695.1.915041.p Protein 2e-33 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP BAC0039 Protein 1e-36 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP001138.1.gene2239. Protein 7e-36 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP000034.1.gene2186. Protein 1e-36 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP BAC0596 Protein 7e-36 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP001918.1.gene3444. Protein 4e-36 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_002695.1.916589.p Protein 1e-36 42
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP AF310956.2.orf0.gene Protein 1e-34 41
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP U35369.1.gene1.p01 Protein 9e-34 41
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP AE016830.1.gene2255. Protein 9e-34 41
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_014475.1.orf0.gen Protein 1e-39 41
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP NC_005054.2598277.p0 Protein 1e-39 41
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP HE999704.1.gene1528. Protein 4e-31 41
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP AF162694.1.orf4.gene Protein 3e-35 41
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP CP004022.1.gene1676. Protein 2e-32 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP VFG1389 Protein 1e-35 46
BCK_12275 YP_006596556.1 DNA-binding response regulator PhoP VFG1386 Protein 2e-40 43