Gene Information

Name : ECENHK_18140 (ECENHK_18140)
Accession : YP_006580083.1
Strain : Enterobacter cloacae ENHKU01
Genome accession: NC_018405
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3878762 - 3880051 bp
Length : 1290 bp
Strand : -
Note : COG1055 Na+/H+ antiporter NhaD and related arsenite permeases

DNA sequence :
ATGTTACTGGCAGGCGCTATTTTTGTCCTGACCCTTGTTTTGGTTATCTGGCAGCCGAAGGGGGTGGGAATTGGCTGGAG
CGCGACGCTGGGCGCAGCCCTGGCTTTAATTTCAGGCGTTGTGCATTTAGGCGATATTCCGGTGGTGTGGAATATCGTCT
GGAACGCGACGGCAACGTTTATTGCCGTCATTATTATTAGCCTGCTGCTTGATGAATCCGGCTTTTTCGAATGGGCAGCG
CTGCATGTTTCGCGTTGGGGAAACGGTCGGGGCCGTTTGCTCTTTACCTATATCGTTCTGCTCGGCGCAGCGGTGGCTGC
ACTGTTTGCCAACGACGGTGCTGCTCTTATTCTGACACCGATCGTGATTGCCATGCTGCTGGCATTAGGGTTCAGCAAAG
GCACCACGCTGGCATTCGTGATGGCCGCCGGCTTTATTGCCGATACCGCCAGCCTGCCGCTTATTGTGTCAAACCTGGTG
AATATTGTTTCGGCAGACTTCTTCGGTCTGGGGTTCACCGAATACGCGTCGGTGATGGTTCCGGTCGATATTGCAGCCAT
TGTCACCACGCTTGTGATGCTGCATCTGTTCTTTCGCAAAGATATCCCGCCGACTTACGAGCTGTCTCTTCTTAAGACAC
CGGCAAAAGCGATTAAAGATCCGGCGACGTTTCGTACCGGCTGGGTCGTTTTAATTCTGTTGCTGGTAGGTTTTTTCGTC
CTTGAGCCGCTCGGTATTCCGGTGAGCGCGATTGCGGCGGTGGGGGCCGTCATCCTGTTTGCCGTGGCGAAACGCGGCCA
TGCCATTAACACGGGCAAAGTGCTGCATGGCGCACCCTGGCAGATCGTCATCTTCTCGCTGGGGATGTACCTGGTGGTCT
ACGGTCTGCGCAACGCCGGGCTTACCGAATACCTTTCAGGTGTGCTGAACGTGCTGGCGGATAAAGGACTCTGGGCCGCG
ACGCTGGGTACCGGCTTCCTGACGGCTTTCCTGTCTTCCATCATGAATAACATGCCGACCGTGCTGGTTGGGGCGCTCTC
TATTGATGGCAGCACCGCAACCGGTGTTATCAAAGAGGCGATGATCTACGCCAACGTGATTGGCTGCGACCTGGGGCCAA
AAATCACCCCTATTGGGAGCCTGGCAACGCTGCTCTGGCTGCATGTCCTTTCACAGAAGAACATGACGATTACCTGGGGA
TATTATTTCCGCACCGGGATCGTTATGACTCTGCCTGTGCTATTTGTAACGCTGGCCGCGCTGGCGCTACGTCTCTCTTT
CACTTTGTAA

Protein sequence :
MLLAGAIFVLTLVLVIWQPKGVGIGWSATLGAALALISGVVHLGDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAA
LHVSRWGNGRGRLLFTYIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFGLGFTEYASVMVPVDIAAIVTTLVMLHLFFRKDIPPTYELSLLKTPAKAIKDPATFRTGWVVLILLLVGFFV
LEPLGIPVSAIAAVGAVILFAVAKRGHAINTGKVLHGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADKGLWAA
TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTATGVIKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTITWG
YYFRTGIVMTLPVLFVTLAALALRLSFTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 2e-167 94
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 5e-100 59
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 5e-98 58
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-101 58

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECENHK_18140 YP_006580083.1 arsenical pump membrane protein BAC0578 Protein 2e-171 97
ECENHK_18140 YP_006580083.1 arsenical pump membrane protein BAC0576 Protein 2e-170 97
ECENHK_18140 YP_006580083.1 arsenical pump membrane protein BAC0031 Protein 2e-166 94
ECENHK_18140 YP_006580083.1 arsenical pump membrane protein BAC0577 Protein 2e-160 91
ECENHK_18140 YP_006580083.1 arsenical pump membrane protein BAC0575 Protein 7e-103 59
ECENHK_18140 YP_006580083.1 arsenical pump membrane protein BAC0574 Protein 2e-100 59