Gene Information

Name : guaA (ECENHK_16370)
Accession : YP_006579735.1
Strain : Enterobacter cloacae ENHKU01
Genome accession: NC_018405
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 3503947 - 3505524 bp
Length : 1578 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGACGGAAAACATTCATAAACATCGCATCCTCATCCTCGATTTTGGTTCTCAGTACACTCAGCTGGTGGCGCGTCGCGT
ACGTGAACTGGGCGTTTACTGCGAACTGTGGGCGTGGGATGTCACGGAAGCACAGATTCGCGAATTCAATCCAAGCGGCA
TCATCCTGTCCGGCGGCCCGGAAAGCACCACCGAAGAGAACAGCCCGCGCGCGCCGCAGTACGTGTTCGAAGCAGGCGTG
CCGGTATTCGGTGTCTGCTACGGTATGCAGACCATGGCCATGCAGCTGGGCGGCCACGTAGAAGGCTCTAACGAGCGTGA
GTTCGGCTATGCACAGGTAGAAGTCGTCACCGACAGCGCACTGGTGCGTGGTATCGAAGACTCCCTGACCGCTGACGGCA
AACCGCTGCTGGACGTGTGGATGAGCCACGGCGACAAGGTCACCGCTATCCCGTCTGATTTCGTAACCGTTGCCAGCACC
GAAAGCTGCCCGTTCGCTATCATGGCGAACGAAGAAAAGCGCTTCTACGGCGTGCAGTTCCATCCGGAAGTGACCCACAC
CCGTCAGGGTATGCGCATGCTGGAGCGCTTCGTGCGCGACATCTGCCAGTGTGAAGCGCTGTGGACCCCGGCAAAAATCA
TCGACGACGCCGTGGAGCGTATCCGCCAGCAGGTTGGTGATGACAAAGTGATCCTCGGCCTCTCCGGCGGCGTCGACTCC
TCCGTGACCGCGATGCTGCTGCACCGTGCCATCGGCAAAAACCTGACCTGCGTCTTCGTGGACAACGGTCTGCTGCGTCT
GAACGAAGCCCAGCAGGTGATGGACATGTTCGGTGACCACTTCGGTCTGAACATCGTTCATGTGGAAGGCGAGCAGCGCT
TCCTGGACGCGCTGAAAGGCGAGAACGATCCGGAAGCCAAGCGTAAAATCATCGGCCGCGTATTCGTGGAAGTGTTCGAC
GAAGAAGCGCTGAAGCTGGAAGACGTTAAATGGCTGGCACAGGGCACTATCTATCCTGACGTGATTGAATCAGCTGCTTC
AGCAACCGGTAAAGCACACGTCATCAAATCTCACCACAACGTGGGCGGCCTGCCGAAAGAGATGAAGATGGGTCTGGTTG
AACCGCTGCGCGAGCTGTTCAAAGATGAAGTACGCAAGATCGGTCTGGAACTGGGTCTGCCGTACGACATGCTCTACCGT
CACCCGTTCCCGGGCCCGGGGCTCGGCGTGCGCGTACTGGGTGAAGTGAAGAAAGAGTACTGCGACCTGCTGCGTCGCGC
AGACGCGATCTTCATCGAAGAGCTGCACAAAGCTGACCTTTACAACAAGGTAAGCCAGGCGTTCACCGTGTTCCTGCCGG
TTCGCTCTGTCGGCGTGATGGGTGATGGCCGTAAGTACGACTGGGTTGTCTCCCTGCGTGCGGTGGAAACCATCGACTTC
ATGACCGCGCACTGGGCGCACCTGCCGTATGACTTCTTAGGCCGCGTGTCTAACCGCATCATCAACGAAGTGAACGGTAT
TTCCCGCGTGGTGTATGACATCAGCGGTAAGCCACCGGCTACGATTGAATGGGAATAA

Protein sequence :
MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIREFNPSGIILSGGPESTTEENSPRAPQYVFEAGV
PVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVVTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVERIRQQVGDDKVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAQQVMDMFGDHFGLNIVHVEGEQRFLDALKGENDPEAKRKIIGRVFVEVFD
EEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-128 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-128 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-128 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-111 48