Gene Information

Name : ECENHK_14300 (ECENHK_14300)
Accession : YP_006579331.1
Strain : Enterobacter cloacae ENHKU01
Genome accession: NC_018405
Putative virulence/resistance : Virulence
Product : Aerobactin siderophore biosynthesis protein iucA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3022744 - 3024486 bp
Length : 1743 bp
Strand : +
Note : COG4264 Siderophore synthetase component

DNA sequence :
ATGCGTACTCTGCCCCGCTCCGCCGGTACAGACGTTGCGGCCCAGTGTTTTTTAAACGCCCTGCTGCGCGAAACGACGGA
CTGGCGCTATCTCCCCGCAGCCGCTGCGGATGAGCTGGCGCATATTCATATCCCGCTTTCTCCCGCTCAGGCCCTGCGGG
TTCCGGTACGCTATTTCTCCCCCACCCAGCACCATCAGTACTGTTTCCCGGCAATGCTTATCCAGAGCGATAGCGACTGC
GGTGACGCCGTCACATATACCCAACTGGTTGATTTACTTCTTGAAAAACCATCAGTAAAAGGCGTTCTTGATGCCGATAC
GCTGGCGCGTTTTAAGCAACGCGTGCTGGAAAGTCATGCGCATACCTGGCAGGCGATCGACCTGCGCCACAGCTGGTCCA
CGCTGCGTGATAAACCGCTGACGTTTGCTGAAGCAGAACAGGCGCTGCTGGTCGGCCACGCATTTCACCCGGCACCGAAG
TCGCACGAGCCATTCAACGAAACCGAAGCGCGACGCTATCTGCCTGATTTTGCCTCCCGTTTCCCGCTGCGCTGGTTTGC
CGTTGAGAGCACGCGCATTGCTGGTGACAGCCTGAACGTCTCCCTGCGCGAACGTCTGCTGCGCTTCGCCGCCCAGAGCG
CGCCTGAGCTGCTCGGCCACTTCACCGACACGCGCTGGCTGTTGCCTATGCACCCATGGCAGGCAGAGCATCTGCTGGGT
CAGGCCTGGTGCCAGCGTCTGGTGGAAAACGGTTCATTGCAGGATCTGGGCGAAGCGGGCGCACAGTGGCTGCCCACCAG
CTCGTCCCGCTCGCTGTACTGCGAATCCAACAGCGACATGATTAAATTCTCCCTCAGCGTGCGCCTGACCAATTCCGTCC
GCACGCTGTCGGTGAAAGAAGTTAAGCGCGGGATGCGCCTGGCGCGCCTGGCGAAAACGGAACGCTGGCAAACGCTTCAG
GCACGCTACCCGACGATGCGCGTGATGCAGGAAGATGGCTGGGCGGGGTTGCGTGACGAAAACGGCGTGGTGCAGGAAGA
GAGCCTGATGGCCCTGCGCGTCAATCTGCTGTTTGACACGCCGGACACGCAGACCAACGTGCTGGTCAGCCTGACCCAGG
CTGCCCCGGATGGCGGTGACAGCCTGCTGGCTGCGGCAGTGCGTCGTCTGAGCCAGCGTCTGGATTTACCCCTCGCTCAG
GCCGCACGCTGCTGGCTGGACGCCTATTGCGACCGCGTGTTACTTCCCCTGTTCAGCGCCGAGGCGGACTACGGCCTGGT
GCTGCTCGCCCACCAGCAAAATATCCTGGTTGAGATGCAGCAGGATTTCCCCGTCGGGCTTATCTACCGTGACTGCCAGG
GCAGCGCCTGGACCGAAGGAGCCGACGGGTGGCTGAAAGAGGCGGGTGAAACTGACGTGGAAAACCGCTTCGGTGAGAGC
CAGCTGCTGCGCTACTTCCCTTACTACCTGCTGCTGAACTCCACCCTTGCGGTGACTGCCGCCCTTGCCGCCGCCGGTTT
CGACAGTGAAGAGCGCCTGATGGCGCGCGTACGTGACGCGCTGGTCTCGCTGCGCCGTACGGCGAAGCAGACCCGCTGCC
TTGACTACGTGCTGGACAGCCCGACCTGGAACTGCAAAGGCAACTTCTTCTGTTATCTGCACGATCGCAACGAAAACACC
ATCGCCGATCCGGCGGTGATCTATTTCGACTTTAGCAACCCGTTCTACAAGGAGAAGGCGTAA

Protein sequence :
MRTLPRSAGTDVAAQCFLNALLRETTDWRYLPAAAADELAHIHIPLSPAQALRVPVRYFSPTQHHQYCFPAMLIQSDSDC
GDAVTYTQLVDLLLEKPSVKGVLDADTLARFKQRVLESHAHTWQAIDLRHSWSTLRDKPLTFAEAEQALLVGHAFHPAPK
SHEPFNETEARRYLPDFASRFPLRWFAVESTRIAGDSLNVSLRERLLRFAAQSAPELLGHFTDTRWLLPMHPWQAEHLLG
QAWCQRLVENGSLQDLGEAGAQWLPTSSSRSLYCESNSDMIKFSLSVRLTNSVRTLSVKEVKRGMRLARLAKTERWQTLQ
ARYPTMRVMQEDGWAGLRDENGVVQEESLMALRVNLLFDTPDTQTNVLVSLTQAAPDGGDSLLAAAVRRLSQRLDLPLAQ
AARCWLDAYCDRVLLPLFSAEADYGLVLLAHQQNILVEMQQDFPVGLIYRDCQGSAWTEGADGWLKEAGETDVENRFGES
QLLRYFPYYLLLNSTLAVTAALAAAGFDSEERLMARVRDALVSLRRTAKQTRCLDYVLDSPTWNCKGNFFCYLHDRNENT
IADPAVIYFDFSNPFYKEKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucA NP_839223.1 siderophore biosynthesis protein Virulence SHI-2 Protein 2e-172 65
iucA NP_709454.2 siderophore biosynthesis protein Virulence SHI-2 Protein 2e-172 65
iucA AAD44746.1 IucA Virulence SHI-2 Protein 1e-172 65
iucA YP_002414046.1 aerobactin siderophore biosynthesis protein Virulence Not named Protein 9e-173 65
iucA AAK71631.1 IucA Virulence SHI-3 Protein 1e-156 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECENHK_14300 YP_006579331.1 Aerobactin siderophore biosynthesis protein iucA VFG0615 Protein 7e-173 65
ECENHK_14300 YP_006579331.1 Aerobactin siderophore biosynthesis protein iucA VFG0940 Protein 4e-173 65
ECENHK_14300 YP_006579331.1 Aerobactin siderophore biosynthesis protein iucA VFG1081 Protein 8e-157 61