Gene Information

Name : hpcC (PGA1_c32220)
Accession : YP_006574588.1
Strain : Phaeobacter gallaeciensis DSM 17395
Genome accession: NC_018290
Putative virulence/resistance : Virulence
Product : 5-carboxymethyl-2-hydroxymuconic semialdehyde dehydrogenase HpcC
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.-
Position : 3378491 - 3380002 bp
Length : 1512 bp
Strand : -
Note : -

DNA sequence :
ATGAGCCAGCTCGACAGCAATATCGGCAAATTGGAGAGCTATCTTGCGCGGTTCCGCGACACAGGGATCCGGAATCGGAT
CGCAGGCGCGGATGTGGCCGGAGGGGCTGGCGTGTTCCAGACCATATCCCCGGTCGACAAAAGCGTGATCTGTGATGTGG
CGCATGGGACGGCGGCTGACATTGATGCTGCTGCTCAGGCTGCGCGACAGGCCTTCGCGGAATGGCGGGATCTGCCTGCG
GTCCAGCGCAAGAAAATTCTGATCCGCATTGCAGAGGGCATTGAGGCGCGTGCAGAGGAGATCGCACTCTGTGAATGCTG
GGATACCGGCCAAGCCTACAAATTCATGTCCAAGGCCGCCCTGCGCGGGGCCGAGAATTTTCGCTATTTTGCTGATCAGG
TGGTGCAGGCCCGGGACGGGCAGCACCTGCAATCCCCGACGCTGATGAATGTGACCACCCGTGTGCCTATCGGCCCGGTT
GGGGTGATCACCCCCTGGAACACGCCCTTCATGCTCTCGACCTGGAAGATTGCGCCGGCGCTTGCTGCGGGATGCACGGT
TGTCCACAAACCCGCCGAAGCGTCGCCGCTGACAGCCCGCCTGCTTGTCGAAATCGCTGAGGAGGCCGGCCTGCCGCCGG
GAGTGCTGAATACGGTCAACGGGTTTGGCGATGAGGCGGGCAAGGCGCTTTGCGAACATCCGGCGATTAGGGCCATCGCC
TTCGTCGGGGAGTCGCGCACCGGCAGCCTGATTACCAAACAGGGCGCAGACACACTGAAACGCAACCATCTCGAATTGGG
CGGCAAAAACCCTGTCATCGTTTTTGAGGATGCAGATCTTGAGCGCGCTCTGGATGCAGTGATTTTCATGATCTACTCGA
TCAACGGGGAACGCTGCACCTCCTCGTCGCGGTTGCTGATACAAGACAGTATAAGGGACGATTTTGAAGCCCGGCTGATC
GAGCGCATCAACAATATCAAGGTTGGTCACCCGCTGGACCCCACGACAGAAATCGGGCCGCTTGTCAGCGAAGAGCATTT
CAACAAGGTCACCAGCTATTTCGATATTGCGACGAAAGAGGGCGCAACCATTGCGGCCGGCGGCGAACCCGTAGGCGAAG
AGGGGTATTTCATAAGGCCCACCCTGTTCACGGATGCGCGCAATGACATGCGTATCGCTCAGGAGGAGATCTTTGGCCCG
GTGCTGACATCGATCCCGTTTACCACCGAAGCAGAGGCGCTGGCGCTGGCCAATGACACGGCGTACGGGCTTACCGGCTA
TCTCTGGACCAACGATCTAACTCGGGCGCTGCGCTTCACCGACAGGCTGGAAGCGGGCATGATCTGGGTGAACTCAGAGA
ATGTGCGCCATCTACCAACGCCCTTCGGTGGCGTCAAAGCCTCCGGTATTGGTCGCGACGGCGGCGATTGGTCGTTTGAA
TTCTACATGGAGCAAAAACACATCGGTTTCGCCACCGGCTCCCACAAGATTACGAAGTTAGGAGCGCTCTGA

Protein sequence :
MSQLDSNIGKLESYLARFRDTGIRNRIAGADVAGGAGVFQTISPVDKSVICDVAHGTAADIDAAAQAARQAFAEWRDLPA
VQRKKILIRIAEGIEARAEEIALCECWDTGQAYKFMSKAALRGAENFRYFADQVVQARDGQHLQSPTLMNVTTRVPIGPV
GVITPWNTPFMLSTWKIAPALAAGCTVVHKPAEASPLTARLLVEIAEEAGLPPGVLNTVNGFGDEAGKALCEHPAIRAIA
FVGESRTGSLITKQGADTLKRNHLELGGKNPVIVFEDADLERALDAVIFMIYSINGERCTSSSRLLIQDSIRDDFEARLI
ERINNIKVGHPLDPTTEIGPLVSEEHFNKVTSYFDIATKEGATIAAGGEPVGEEGYFIRPTLFTDARNDMRIAQEEIFGP
VLTSIPFTTEAEALALANDTAYGLTGYLWTNDLTRALRFTDRLEAGMIWVNSENVRHLPTPFGGVKASGIGRDGGDWSFE
FYMEQKHIGFATGSHKITKLGAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-88 48
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-73 43
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-73 43
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-73 43
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-72 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-73 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hpcC YP_006574588.1 5-carboxymethyl-2-hydroxymuconic semialdehyde dehydrogenase HpcC VFG0082 Protein 3e-73 42