Gene Information

Name : prrA (MSMEI_5513)
Accession : YP_006570248.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_018289
Putative virulence/resistance : Virulence
Product : Two component transcriptional regulator, winged helix family
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5757064 - 5757774 bp
Length : 711 bp
Strand : +
Note : -

DNA sequence :
ATGGACAGTACTACCAGCGGCATGGCCTCGCCGAGGGTGCTTGTGGTGGATGACGACCCCGACGTGCTCGCCTCACTCGA
ACGCGGGCTGCGGCTGTCCGGATTCGACGTGTCGACAGCCGTGGACGGGGCCGAGGCGCTGCGCAGCGCCACCGAGACGC
GCCCCGACGCCATCGTGCTCGACATCAACATGCCCGTCCTCGACGGTGTCAGCGTGGTGACCGCGCTCCGCGCCATGGAC
AACGACGTGCCGGTGTGCGTGTTGTCCGCGCGCAGCAGTGTCGACGACCGCGTCGCGGGGCTCGAAGCCGGCGCCGACGA
CTACCTGGTGAAACCGTTCGTGCTGGCCGAACTCGTGGCGCGGGTCAAGGCGCTGCTGCGCCGCCGCGGCTCGTCGGCCA
CGTTCTCGTCGGAGACCATCCAGGTCGGCCCGCTCGAGGTGGACATCCCGGGCCGTCGCGCGCGCGTCAACGGCGTCGAC
GTCGACCTGACCAAGCGCGAGTTCGACCTGCTCGCCGTGCTGGCCGAGCACAAGACCGCGGTGCTCTCGCGCGCCCAGCT
GCTCGAGCTGGTGTGGGGCTACGACTTCGCGGCCGACACCAACGTCGTCGACGTGTTCATCGGCTACCTGCGCCGGAAGC
TCGAAGCCGGTGGCGCGCCCCGATTGCTGCACACCGTGCGAGGCGTCGGTTTCGTCCTGCGGACCCAGTAG

Protein sequence :
MDSTTSGMASPRVLVVDDDPDVLASLERGLRLSGFDVSTAVDGAEALRSATETRPDAIVLDINMPVLDGVSVVTALRAMD
NDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSSATFSSETIQVGPLEVDIPGRRARVNGVD
VDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRTQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-25 42
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 6e-25 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family BAC0083 Protein 7e-32 46
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family BAC0125 Protein 2e-30 45
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family BAC0197 Protein 6e-25 44
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family AE000516.2.gene3505. Protein 1e-28 44
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_003923.1003417.p0 Protein 2e-32 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_013450.8614146.p0 Protein 2e-32 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_002951.3238224.p0 Protein 2e-32 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_007793.3914065.p0 Protein 2e-32 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_002758.1121390.p0 Protein 2e-32 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_010079.5776364.p0 Protein 2e-32 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_002952.2859858.p0 Protein 2e-32 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_007622.3794948.p0 Protein 2e-32 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family HE999704.1.gene1528. Protein 3e-31 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family BAC0111 Protein 7e-27 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_012469.1.7685629. Protein 1e-27 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family BAC0638 Protein 5e-24 42
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family BAC0308 Protein 3e-27 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_002952.2859905.p0 Protein 2e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_002745.1124361.p0 Protein 3e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_009782.5559369.p0 Protein 3e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_002951.3237708.p0 Protein 3e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_003923.1003749.p0 Protein 3e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_002758.1121668.p0 Protein 3e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_007622.3794472.p0 Protein 2e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_009641.5332272.p0 Protein 3e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_013450.8614421.p0 Protein 3e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family NC_007793.3914279.p0 Protein 3e-28 41
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family HE999704.1.gene2815. Protein 6e-27 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family VFG1389 Protein 7e-84 94
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family VFG1390 Protein 1e-41 50
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family VFG1386 Protein 7e-36 45
prrA YP_006570248.1 Two component transcriptional regulator, winged helix family VFG0596 Protein 6e-26 42