Gene Information

Name : ureC (MSMEI_3540)
Accession : YP_006568298.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_018289
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 3688993 - 3690726 bp
Length : 1734 bp
Strand : -
Note : -

DNA sequence :
ATGACCGCACTGTCACGGAGCAACTACGCCGCGCTGTTCGGTCCCACCACCGGGGACCGCATCCGGCTGGCCGACACCGA
CCTGCTGATCGAGATCACCGAGGACCGCAGCGGCGGACCGGAGCTCGCCGGTGACGAGGCCGTGTTCGGCGGCGGCAAGG
TGTTGCGCGAGTCCATGGGGCAGGGCCGGGCCACCCGCGCCGACGGCGCCCCCGACACCGTCATCACCGGAGCGGTGATC
CTCGACCACTGGGGGATCATCAAGGCCGACATCGGGATCCGCGACGGCCGGATCGTTGCGATCGGCAAGGCGGGCAACCC
CGACATCATGTCGGGCGTGCACCCCGATCTGGTGGTCGGCCCGTCCACCGAGATCATCGCGGGCAACGGTCGCATCCTCA
CCGCGGGTGCCATCGACTGCCACGTGCACCTGATCTGCCCGCAGATCATGGACGAGGCGCTCGGCGGCGGCATCACCACG
ATCATCGGCGGCGGCACCGGCCCGGCCGAGGGCACCAAGGCCACCACGGTCACGCCGGGCGCATGGCATCTGGCGCGCAT
GCTCGAGTCCCTGGACTCCTGGCCCATGAACATCGTGCTGCTGGGCAAGGGCAACACCGTCAGCGCCGACTCGATGTGGG
AGCAGTTGCGCGGCGGCGCAGCGGGTTTCAAGCTCCACGAGGATTGGGGCACCACCCCGGCGGCCATCGACGCGTGCCTT
ACGGTGTGCGACGCCGCAGGCGTGCAGGCGGCCATCCACACCGACACGCTCAACGAGATGGGCTTCGTCGAGGACACCCT
GGCCGCCATCGGCGGCCGCTCGATCCACGCCTACCACACCGAGGGTGCCGGCGGCGGGCACGCGCCGGACATCATCACGG
TGGCGGGCCATCCCAACGTGCTGCCCAGCTCCACCAACCCGACCCGGCCGCACACCGTCAACACCCTCGACGAGCACCTG
GACATGCTGATGGTCTGCCATCACCTGAAACCCAGTGTGCCCGAGGATCTCGCGTTCGCCGAGAGCCGTATCAGGCCGTC
GACCATCGCGGCCGAGGACCTGCTGCACGACATCGGGGCCATCTCGATGATCGGCAGTGACGCGCAGGCCATGGGCCGCA
TCGGCGAGGTCGTGATGCGCACCTGGCAGACCGCGCACGTGATGAAGCGCCGCCGCGGCGCGCTGGAAGGCGACGGCTCT
GGGAAGAACGGCGCGGACAACCTGCGCGCGCGCCGCTACGTCGCCAAGTACACGATCTGTCCCGCGGTCGCGCACGGCCT
CGACCACGAGATCGGCTCGGTCGAGGTCGGCAAGCTCGCGGATCTGGTGCTGTGGGAGCCCGCGTTCTTCGGGGTGCGCC
CGCATGCGGTGATCAAGGGCGGCATGATCGCGTGGGCCGCGATGGGCGACGCCAACGCGTCGATCCCGACACCGCAGCCC
GTGCTGCCGCGGCCCATGTTCGGAGCCGCACCGGCCGCAGCGGCCGCGACCTCGGTGCACTTCGTGGCGCCGCAGGCCAT
CGAGGACGGCCTGGCCGAACGCATCGACGTCAGGCGGAAACTCGTCGCGGTCAAGGACGTCCGCAAGGTCGGCAAGGCGC
AGATGCCGCTCAACGACGCGCTGCCACGCATCGAGGTCGAACCCGACACGTTCACGGTGCGCATCGACGGCGAGGTGTGG
GACGAACAACCCGCCGCCGAGCTACCCATGGCACAGCGATACTTCCTGTTCTAG

Protein sequence :
MTALSRSNYAALFGPTTGDRIRLADTDLLIEITEDRSGGPELAGDEAVFGGGKVLRESMGQGRATRADGAPDTVITGAVI
LDHWGIIKADIGIRDGRIVAIGKAGNPDIMSGVHPDLVVGPSTEIIAGNGRILTAGAIDCHVHLICPQIMDEALGGGITT
IIGGGTGPAEGTKATTVTPGAWHLARMLESLDSWPMNIVLLGKGNTVSADSMWEQLRGGAAGFKLHEDWGTTPAAIDACL
TVCDAAGVQAAIHTDTLNEMGFVEDTLAAIGGRSIHAYHTEGAGGGHAPDIITVAGHPNVLPSSTNPTRPHTVNTLDEHL
DMLMVCHHLKPSVPEDLAFAESRIRPSTIAAEDLLHDIGAISMIGSDAQAMGRIGEVVMRTWQTAHVMKRRRGALEGDGS
GKNGADNLRARRYVAKYTICPAVAHGLDHEIGSVEVGKLADLVLWEPAFFGVRPHAVIKGGMIAWAAMGDANASIPTPQP
VLPRPMFGAAPAAAAATSVHFVAPQAIEDGLAERIDVRRKLVAVKDVRKVGKAQMPLNDALPRIEVEPDTFTVRIDGEVW
DEQPAAELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-160 61
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-160 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-155 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-155 56
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-155 56
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-155 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_006568298.1 urease subunit alpha VFG0270 Protein 3e-140 55