Gene Information

Name : MSMEI_1506 (MSMEI_1506)
Accession : YP_006566274.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_018289
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD+)
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 1634948 - 1636471 bp
Length : 1524 bp
Strand : +
Note : -

DNA sequence :
ATGACTGTTTACGCACGTCCGGGCGCAGACGGCGCCAAGATGTCGTTCCAGGCCCGCTACGACAACTACATCGGCGGCGA
GTGGGTCGCCCCGGTCGAGGGCCGCTACTTCGAGAATCCGACGCCGGTGACCGGTCAGGTGTTCTGCGAGGTGGCCCGCT
CCAGCGAGGCCGACATCGACAAGGCTCTCGACGCCGCACACGCCGCGGCGCCCGCGTGGGGCAAGACCGCCCCGGCCGAG
CGCGCGCTGATCCTCAACCGCATCGCCGATCGCATGGAGGAGAACCTCGAATCCATCGCGCTGGCCGAGTCGTGGGACAA
CGGCAAGCCGATCCGCGAGACGCTCAACGCCGACATCCCGCTGGCCATCGACCACTTCCGCTACTTCGCGGGCGTGCTGC
GTGCCCAGGAAGGCTCGCTGAGCCAGATCGACGAGGACACCGTCGCCTACCACTTCCACGAGCCGCTGGGCGTGGTCGGG
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCGGTGTGGAAGCTGGCCCCGGCCCTGGCTGCGGGCAACGCCGTCGT
CCTCAAGCCCGCCGAGCAGACCCCTGTCTCGGTGCTCTACCTGTTCTCACTCATCGGCGACCTGCTGCCCGCCGGTGTGG
TCAACATCGTCAACGGGTTCGGTGTGGAGGCCGGCAAGCCGCTGGCGTCGAGCAACCGCATCGCCAAGATCGCGTTCACC
GGTGAGACCACCACGGGCCGGCTGATCATGCAGTACGCGTCGCAGAACCTGATCCCGGTGACCCTGGAACTCGGCGGCAA
GAGCCCCAACATCTTCTTCAACAACGTGCTCGCGCAGGCCGACGACTACCAGGACAAGGCGCTGGAGGGCTTCACGATGT
TCGCCCTCAACCAGGGTGAGGTGTGCACGTGCCCGTCGCGGTCGCTGATCCAGTCCGACATCTTCGACGAGTTCCTCGAG
CTCGCCGCGATCCGCACCAAGGCCGTGCGCCAGGGCGATCCGCTGGACACCGAGACCATGATCGGTGCGCAGGCGTCCAA
CGATCAGCTGGAGAAGATCCTGTCCTACATCGAGATCGGCAAATCCGAAGGGGCCAAGCTGATCACGGGGGGAGAGCGTG
CGCAGCTCGGCGGCGATCTCAACGGCGGCTACTACGTGGCGCCGACGATCTTCACGGGCAACAACAAGATGCGCATCTTC
CAGGAGGAGATCTTCGGCCCGGTCGTGGCGGTCACGTCGTTCAGCGACTACGACGACGCCATCTCGATCGCCAATGACAC
GCTCTACGGTCTGGGTGCCGGTGTGTGGAGCCGCGACGGCAACATCGCCTACCGCGCGGGCCGCGACATCAAGGCCGGCC
GGGTGTGGACCAACTGCTACCACCAGTACCCCGCGCACGCCGCGTTCGGTGGCTACAAGCAGTCCGGCATCGGGCGTGAG
ACCCACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTTTCGTACAGCAACAAGGCCCAGGGATTCTT
CTGA

Protein sequence :
MTVYARPGADGAKMSFQARYDNYIGGEWVAPVEGRYFENPTPVTGQVFCEVARSSEADIDKALDAAHAAAPAWGKTAPAE
RALILNRIADRMEENLESIALAESWDNGKPIRETLNADIPLAIDHFRYFAGVLRAQEGSLSQIDEDTVAYHFHEPLGVVG
QIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPVSVLYLFSLIGDLLPAGVVNIVNGFGVEAGKPLASSNRIAKIAFT
GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNNVLAQADDYQDKALEGFTMFALNQGEVCTCPSRSLIQSDIFDEFLE
LAAIRTKAVRQGDPLDTETMIGAQASNDQLEKILSYIEIGKSEGAKLITGGERAQLGGDLNGGYYVAPTIFTGNNKMRIF
QEEIFGPVVAVTSFSDYDDAISIANDTLYGLGAGVWSRDGNIAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRE
THKMMLDHYQQTKNLLVSYSNKAQGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-143 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-152 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-152 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-152 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-151 61
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-69 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MSMEI_1506 YP_006566274.1 aldehyde dehydrogenase (NAD+) VFG0082 Protein 6e-144 62