Gene Information

Name : MSMEI_1062 (MSMEI_1062)
Accession : YP_006565837.1
Strain : Mycobacterium smegmatis MC2 155
Genome accession: NC_018289
Putative virulence/resistance : Virulence
Product : Urease alpha subunit, (Urea amidohydrolase alpha subunit)
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 1159353 - 1161059 bp
Length : 1707 bp
Strand : +
Note : -

DNA sequence :
GTGACGACCATCGACCGCCGCGCGTATGCGCGTATGTTCGGGCCCACCAGGGGTGACCGGATCCGGCTCGCCGATTCGGA
TCTGTTCGTCGAGGTCGAGCACGACCACACCGTGGCGGGCTACGAGTTGCTCAGTGGCGCAGGCAAATCCGTGCGCGACG
GCGAGGGGTACCGGCCGTCGTCCAAACCGTCCGACGGCGCGCTCGACTACGTCATCATGAACGCCGTCGTGATCGACGCT
GTCGCCGGGATCATCAAGTGCGACATCGGTATCCGCGACGGGCGCATCGTCGGCATCGGCAAGGCGGGCAACCCGGACAC
CATGCCGGGGGTCACCGAAAGCATGGTCGTCGGCAGCGCCACCACGCCGATCCCGGCCGAGGGCATGATCGTCACGGCGG
GTGCCATCGAGACGCACGCGCACCTGATCTCGCCGCAGCAGACCGAACACGCGTTGTCGACGGGCACCACCACGCTCATC
GGCGGTTCACTGGGCCCGTCGTTCGAGGTCGCGACCGGCGGCCCGCGCAACCTCGGCATGTTCCTCAAGGCCGGTGACTA
CACGCCCATGAACTACGTGCCGTTCGGGCGGGGTTCGTCGGATCCGGCCGCGGTGCTGGAGATGGTGGCCGCAGGCGCGG
GCGCGGTCAAGATCCACGAGGACTTCGGCGCCTCGCCCGACATCATCGACAAGACGTTGCAGGCCGCGGATTCCGCAGAT
TTCGCGGTGCATCTGCACACCGATTCGATCAACGAGTTCGGGTTCTCCGAGACCACCATGTTGACGATCGGCGACCGGAC
CATCCACCTCTATCACGTCGAGGGTGCGGGCGGCGGGCACGCACCCGACCTGATCCGGTGCGTGAGCTTCGACAACGTCA
TCCCGGGCACCACCAACCCCACCAACCCGTACACGTTGGGCGGTCTCGACGAAGGTGTGCCGATGACCATGGCGGCGCAC
CTGATGAACTGGGAGTCGCCCGAGGACATCGCATTTGCCGAGGCCCGCATCCGCCCGCAGACCATGGTGGCCGAGGATCT
CCTGCACGACATGGGCGCCATCTCGATCTTCGGCAGCGACACCCAGGGCATGGGGCGAGTCGCGGAGAACATCGCCAACT
GCTGGCAATTGGCCGCGGTCATGAAACAGCGTGTCGGGCGCCTGCCGGAGGAGAAGACCGTCGCGGCCGACAACGAACGC
GTCAAGCGCTACATCGCGAAATTGACCATCAACCCGGCCATCTCGGTCGGCGCCGACGATCACATCGGTTCGGTCGAGGT
GGGCAAGGTCGCCGACCTGGTGATCTGGAAACCCGCGTTCTTCGGCGTCAAACCGCAGGTGGTGCTCAAGAACGGCTACA
TCGCGTGGGCCGCGCTCGGCGATGCGGCCGGGTCCATCTCGTCGTCCGAACCGATCATCCAGCGCCCCAACTGGGCCGCC
CTGGGCGACGCGGCCGCCGACGGCGGATTCGTGTTCATGTCCTCACTGGCCATCGACGCCGGTGTGCCCGAACGCCTCGG
GCTGCGCAAGCATGTACTGCCCATCAAGTCGGTGCGCTCGCTGCGCAAGAAGGACATGGTGCGCAACGACGCCCTGCCGC
ACGTCGAGGTCGATCCGCGCACCTTCGACGTGCGGGCCGACGGGGTACTGCTCACCGCCGAACCCGCTGTCAGCGTGCCG
TTTTCGCGGAAGTTCCTGCTGCGATGA

Protein sequence :
MTTIDRRAYARMFGPTRGDRIRLADSDLFVEVEHDHTVAGYELLSGAGKSVRDGEGYRPSSKPSDGALDYVIMNAVVIDA
VAGIIKCDIGIRDGRIVGIGKAGNPDTMPGVTESMVVGSATTPIPAEGMIVTAGAIETHAHLISPQQTEHALSTGTTTLI
GGSLGPSFEVATGGPRNLGMFLKAGDYTPMNYVPFGRGSSDPAAVLEMVAAGAGAVKIHEDFGASPDIIDKTLQAADSAD
FAVHLHTDSINEFGFSETTMLTIGDRTIHLYHVEGAGGGHAPDLIRCVSFDNVIPGTTNPTNPYTLGGLDEGVPMTMAAH
LMNWESPEDIAFAEARIRPQTMVAEDLLHDMGAISIFGSDTQGMGRVAENIANCWQLAAVMKQRVGRLPEEKTVAADNER
VKRYIAKLTINPAISVGADDHIGSVEVGKVADLVIWKPAFFGVKPQVVLKNGYIAWAALGDAAGSISSSEPIIQRPNWAA
LGDAAADGGFVFMSSLAIDAGVPERLGLRKHVLPIKSVRSLRKKDMVRNDALPHVEVDPRTFDVRADGVLLTAEPAVSVP
FSRKFLLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 8e-100 49
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 8e-100 49
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-97 46
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-96 46
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-96 46
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-96 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MSMEI_1062 YP_006565837.1 Urease alpha subunit, (Urea amidohydrolase alpha subunit) VFG0270 Protein 2e-100 47