Gene Information

Name : merA (MRBBS_0156)
Accession : YP_006556507.1
Strain : Marinobacter sp. BSs20148
Genome accession: NC_018268
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 162130 - 163533 bp
Length : 1404 bp
Strand : +
Note : -

DNA sequence :
ATGAGTGACAACAACTTGCACATCGTAGTGATTGGCAGCGGCGGTAGTGCCATGGCCGCCGCCCTGAAGGCGACTGAACG
CGGTGCCCGAGTGACACTCATCGAGTGCGGCACCATCGGTGGAACCTGCGTCAACACTGGCTGTGTGCCCTCCAAAATCA
TGATCCGGGCGGCCCACATCGCTCATTTGCGCCGCAAAAGTCCATTTGACGAAAGCATCACGGCGACCGAACCCATAATC
GACCGCCCCCTGTTGCTGGCCCAACAGCAGGCCCGTGTTGATGAACTGCGGCACTCCAAGTATGAAGGGATCTTGGAAGA
AAACCTTGATATCACGGTCGTGCAGGGTGAGGCTCGTTTTATGGATGCCAGTACGGTGCGGGTCAATGGTGCTGACGGCA
AGGAACACGAGATCGGCTTTGACCGTGCGTTCATTGGTACCGGTGCGCGGCCAACCATACCGCCGATTCCGGGCCTGCCC
GATACGCCATACTGGACCTCCACCACTGCGCTTGCCAGTGACACCATTCCGGACCGATTGATTGTCATCGGGGCCTCGGT
GGTGGCGGTGGAACTGGCCCAGGCGTTTGCCCGGCTGGGTAGCGAGGTGACGATTCTGGCACGCAGCAGGCTATTATCTC
GTGAAGACCCCGCTGTTGGAGAAGCCATTCAAACAGCGTTCCAGGCTGAGCGTATAAGCGTCCTGAATGACACGCAGGCG
AGCCAGGTCAGCTATACCAATGATGAGTTCATTGTCGCCTCGAATGCCGGGGAGCTGCGGGCCGATCGACTTCTGGTGGC
GGTGGGTCGCACCCCGAACACTGAAAGGCTGAACCTGAATGCGATCGACGTAGAGACAGATCACGGTGCCGTCATCGTGA
ACGATCAACTCCAGACTCGGGTGCCGGGCATTTACGCCGCTGGCGACTGTACCAACCAGCCCCAGTTTGTTTATGTAGCC
GCCGCCGGAGGCAGCCGGGCTGCGGTGAATATGACCGGCGGCGATGCACGGTTGGATCTCAGCGCCATGCCGGCGGTGGT
CTTTACCAATCCCCAGGTGGCTACTGTCGGCCTGACAGCAGCCGAGGCCGTCAGGCGGGGCTTCAAAGTGGACACCCGTT
CGCTCAATCTGGAAAACGTGCCGCGGGCGCTGGTGAATTTCGAGACTGGCGGTTTTATCAAGATGGTGGCCGAGCGTGGC
TCAGGACGGTTGCTTGGGGTCCAGGCGGTCACCGGCGAGGCGGGTGAACTGATCCAGACGGCGGTGATGGCACTGCGGGC
GCGCATGACCGTGCAAGAGATCGGCGACGAGCTGTTTCCCTATCTCACCATGGTGGAGGGGCTGAAGCTCTGTGCCCAAA
CCTTTACCAAGGACGTCACCAAGTTGTCCTGTTGTGCCGCCTGA

Protein sequence :
MSDNNLHIVVIGSGGSAMAAALKATERGARVTLIECGTIGGTCVNTGCVPSKIMIRAAHIAHLRRKSPFDESITATEPII
DRPLLLAQQQARVDELRHSKYEGILEENLDITVVQGEARFMDASTVRVNGADGKEHEIGFDRAFIGTGARPTIPPIPGLP
DTPYWTSTTALASDTIPDRLIVIGASVVAVELAQAFARLGSEVTILARSRLLSREDPAVGEAIQTAFQAERISVLNDTQA
SQVSYTNDEFIVASNAGELRADRLLVAVGRTPNTERLNLNAIDVETDHGAVIVNDQLQTRVPGIYAAGDCTNQPQFVYVA
AAGGSRAAVNMTGGDARLDLSAMPAVVFTNPQVATVGLTAAEAVRRGFKVDTRSLNLENVPRALVNFETGGFIKMVAERG
SGRLLGVQAVTGEAGELIQTAVMALRARMTVQEIGDELFPYLTMVEGLKLCAQTFTKDVTKLSCCAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AFG30120.1 MerA Not tested PAGI-2 Protein 6e-149 69
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 8e-149 69
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 6e-149 69
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-150 69
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-150 69
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-150 69
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 7e-148 68
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 3e-149 68
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 3e-148 68
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 7e-145 67
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 1e-86 44
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 1e-86 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_006556507.1 mercuric reductase BAC0652 Protein 5e-149 68
merA YP_006556507.1 mercuric reductase BAC0653 Protein 6e-151 68
merA YP_006556507.1 mercuric reductase BAC0650 Protein 1e-147 65
merA YP_006556507.1 mercuric reductase BAC0651 Protein 6e-87 44
merA YP_006556507.1 mercuric reductase BAC0224 Protein 6e-84 42