Gene Information

Name : aadK (EFD32_2820)
Accession : YP_006539177.1
Strain : Enterococcus faecalis D32
Genome accession: NC_018221
Putative virulence/resistance : Resistance
Product : aminoglycoside 6-adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.-
Position : 2901238 - 2902155 bp
Length : 918 bp
Strand : -
Note : -

DNA sequence : 
ATGAGATCAGAAAAGGAAGTTTATGATATTGTTTTGAATTTTGCAAAAACAGACAAACGCATTCGCATGGTTACTTTGGA
AGGATCTAGAACAAATACAAATATTCCGCCTGATGATTTTCAGGATTTTGATATTACTTTTTTTGTTACGGATATGGACA
GCTTCACAAGTGATGATAAATGGCTAGATATATTTGGTGAAAGGTTGATTCTGCAAAAGCCGGAAGATATGGAATTATTT
CCAGCTGTAGAAAAGGGATTTTCATATTTAATGCTGTTTACTGATGATGTTAAGATAGATTTAACTTTGCTGCCGCTGGA
ACTGATAGACGAGTATTTTACATGGGATAAACTGGTAAAGTTACTGTTGGATAAAGACAACCGTATCGTAAAGCCGCCAA
TACCAACGGATATAGACTACCACTTGCAGAAGCCTACTCAAAGAATGTTTGACGATTGCTGTAATGAATTTTGGAATACT
ACAACATATGTAGTAAAGGGCTTATGCCGCAAAGAAATTCTTTTTGCTATTGACCATATGAATGATATAGTACGAAAAGA
ATTGCTTCGCATGATTTCCTGGCTGATTGGTATCAAACAGGGATTTCATTTCAGTTTGGGAAAAAACTATAAATTTATGA
AGCAATATGTCCCAGAGGAATTGTGGGAACGACTTATGTCCACTTATAATATGGATTCCTATCCCCATATGTGGGAATCC
TTTGAACAATGTATGGCATTGTTCCGGGAGGTTTCGTCAGAAGTGGCATGCCAGTTGGATTACCAGTATCCACTATATGA
TGAAAAAATCAGTAATTATGTGATTCGGCAAAAGAAAAATATGGCATTGAAGATGATAACAAATAAAATTTTTTCAATCG
AAAAAATTTATTTTGATTATTCAATTTTGAAAAACTGA

Protein sequence : 
MRSEKEVYDIVLNFAKTDKRIRMVTLEGSRTNTNIPPDDFQDFDITFFVTDMDSFTSDDKWLDIFGERLILQKPEDMELF
PAVEKGFSYLMLFTDDVKIDLTLLPLELIDEYFTWDKLVKLLLDKDNRIVKPPIPTDIDYHLQKPTQRMFDDCCNEFWNT
TTYVVKGLCRKEILFAIDHMNDIVRKELLRMISWLIGIKQGFHFSLGKNYKFMKQYVPEELWERLMSTYNMDSYPHMWES
FEQCMALFREVSSEVACQLDYQYPLYDEKISNYVIRQKKNMALKMITNKIFSIEKIYFDYSILKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 4e-123 99
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 2e-82 64
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 2e-79 63
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 2e-79 63

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadK YP_006539177.1 aminoglycoside 6-adenylyltransferase FN594949.1.gene25.p0 Protein 1e-94 73
aadK YP_006539177.1 aminoglycoside 6-adenylyltransferase NC_006663.1.orf0.gen Protein 1e-75 65