Gene Information

Name : metB (MYCMA_0638)
Accession : YP_006520406.1
Strain : Mycobacterium abscessus GO 06
Genome accession: NC_018150
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 1212492 - 1213664 bp
Length : 1173 bp
Strand : +
Note : -

DNA sequence :
ATGAGTGAGCAGCGCAGCGCCGCCGACGCGTCTCGGTGGCAAGGGTTTTCCACAAGGGCCATCCACGGCGGTTTCCACGC
CGATCCGCAGACCGGTGCGGTCAACGTGCCGATCTACGCCAGTTCGACCTTCGCCCAAGATGGCGTCGGTCAGCTGCGTG
GAGGATTCGAATACGCACGCACCGGAAATCCCACGCGTGCCGTTCTCGAAGCCTCTTTGGCGGCATTGGAAGACGCCCAC
TTCGGCAGGGCGTTCAGTTCCGGGATGGCGGCCACCGACTGCGTGTTGCGCGCGCTGCTGAGGCCGGGCGATCACCTGAT
CATCCCCAACGATGCCTACGGCGGCACCTTCCGTCTGATCGACAAGGTCTTCTCGCAGTGGGGGATCAGTCACACTCCGG
TGCCGGTGGCCGACGTCGATGCCATCCGTGCGGCAATTACCCCCACCACCAAGCTGATCTGGCTGGAGACGCCGACCAAT
CCGCTGCTGAGTATCGCCGATATTGCGGCGGTCGCCCAGGTGGCGGCGGAGCGTTCCGTGAAGCTGTTGGTGGACAACAC
TTTCGCCTCACCGGCGCTGCAGCAGCCGCTGAATCTCGGCGCCGATATCGCGCTGCACTCCACCACCAAATACATTGGCG
GACATTCCGATGTCGTTGGAGGAGCCTTGCTCACCAACGACGAGGAGCTGGACACCGCGTTCGCGTTCCTGCAGAACGGG
GCGGGTGCGGTGCCGGGCCCGTTCGACGGCTACCTGACCTACCGGGGTATCAAGACCTTGGCATTGCGCATGCAGCGACA
CAGCGAGAACGCGCAAGCGGTGGCCGAGTACCTGGCCGGCCACTCCGCCGTCGCGCAGACGATCTACCCGGGGCTGGAAA
GCCACCCGGGACATGCCGTGGCCGCCAGGCAGATGCGTGGCTTCGGCGGCATGGTCAGTGTGCGGTTGGCCGGAGGACGC
CAGGCGGCACTCGACTTGTGCTCGCGAACAGAGCTTTTCATTCTGGCTGAGTCCTTGGGCGGGGTGGAGTCCCTGATCGA
GCACCCGGGAGCCATGACGCACGCGTCGACGGCGGGATCGCTGCTGGAGGTGCCGGACGATCTGGTGCGGTTGTCGGTGG
GCATCGAGGAGGTCGGCGATCTGATCGGCGACCTCGAGCAGGCGTTGCGTTAA

Protein sequence :
MSEQRSAADASRWQGFSTRAIHGGFHADPQTGAVNVPIYASSTFAQDGVGQLRGGFEYARTGNPTRAVLEASLAALEDAH
FGRAFSSGMAATDCVLRALLRPGDHLIIPNDAYGGTFRLIDKVFSQWGISHTPVPVADVDAIRAAITPTTKLIWLETPTN
PLLSIADIAAVAQVAAERSVKLLVDNTFASPALQQPLNLGADIALHSTTKYIGGHSDVVGGALLTNDEELDTAFAFLQNG
AGAVPGPFDGYLTYRGIKTLALRMQRHSENAQAVAEYLAGHSAVAQTIYPGLESHPGHAVAARQMRGFGGMVSVRLAGGR
QAALDLCSRTELFILAESLGGVESLIEHPGAMTHASTAGSLLEVPDDLVRLSVGIEEVGDLIGDLEQALR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-73 48
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-72 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-57 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_006520406.1 cystathionine gamma-synthase BAC0207 Protein 1e-61 42