Gene Information

Name : mprA (MYCMA_0574)
Accession : YP_006520346.1
Strain : Mycobacterium abscessus GO 06
Genome accession: NC_018150
Putative virulence/resistance : Virulence
Product : response regulator mprA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1090211 - 1090903 bp
Length : 693 bp
Strand : +
Note : -

DNA sequence : 
GTGCCTGTGCGAATTCTTGTAGTCGACGACGATCGTGCTGTGCGCGAGTCGTTGCGGCGTTCCTTGTCCTTCAATGGGTA
CTCGGTCGATCTGGCCGAGGATGGTGTCGACGCGTTGAATGTGATCGCCAACGATCGCCCCGACGCATTGGTGCTCGACG
TCATGATGCCCAAGCTCGACGGCCTTGAGGTGTGTCGTCGCCTGCGCAGCACGGGGGATGATCTGCCGATCCTGGTCCTT
ACCGCTCGCGATTCGGTCTCGGAGCGAGTGGCCGGGCTGGATGCGGGCGCCGACGACTACCTGCCCAAGCCCTTTGCGCT
GGAGGAGCTGCTGGCCCGGATGCGCGCGCTGCTGCGCCGCACCACGATCGACGAATCGGCCGATGCCGCCACGCTCAGCT
TCGGCGATCTGACACTGGACCCCGTCACGCGTGAGGTGCATCGAGGCACCCGGTCGATCAGCCTGACGCGCACGGAATTT
GCGCTGCTTGAAATGCTCATGGCCAATCCCCGGCGGGTGCTCACCCGCAGCCGCATCCTCGAAGAGGTATGGGGGTTCGA
CTTCCCGACGTCCGGTAATGCCCTCGAGGTGTACGTCGGCTACCTACGACGCAAGACCGAGGCCGAAGGGGAGCTCCGGC
TCATTCACACCGTCCGCGGTGTCGGCTACGTGCTGCGGGAGACCCCTCCGTAA

Protein sequence : 
MPVRILVVDDDRAVRESLRRSLSFNGYSVDLAEDGVDALNVIANDRPDALVLDVMMPKLDGLEVCRRLRSTGDDLPILVL
TARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTTIDESADAATLSFGDLTLDPVTREVHRGTRSISLTRTEF
ALLEMLMANPRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKTEAEGELRLIHTVRGVGYVLRETPP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-31 41
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-30 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mprA YP_006520346.1 response regulator mprA BAC0083 Protein 8e-35 47
mprA YP_006520346.1 response regulator mprA HE999704.1.gene1528. Protein 1e-38 46
mprA YP_006520346.1 response regulator mprA BAC0125 Protein 1e-34 45
mprA YP_006520346.1 response regulator mprA BAC0638 Protein 3e-28 45
mprA YP_006520346.1 response regulator mprA BAC0308 Protein 3e-32 44
mprA YP_006520346.1 response regulator mprA BAC0347 Protein 5e-29 42
mprA YP_006520346.1 response regulator mprA BAC0111 Protein 1e-33 42
mprA YP_006520346.1 response regulator mprA BAC0197 Protein 5e-30 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mprA YP_006520346.1 response regulator mprA VFG1390 Protein 8e-85 88
mprA YP_006520346.1 response regulator mprA VFG1386 Protein 5e-44 50
mprA YP_006520346.1 response regulator mprA VFG1389 Protein 2e-42 50
mprA YP_006520346.1 response regulator mprA VFG0596 Protein 9e-32 41