Gene Information

Name : aldA (MYCMA_0515)
Accession : YP_006520288.1
Strain : Mycobacterium abscessus GO 06
Genome accession: NC_018150
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 979513 - 981033 bp
Length : 1521 bp
Strand : +
Note : -

DNA sequence :
ATGGCGAAGTACGCGGCACCCGGAACCGAGGGCAGTGCAGTCACTTTCGCGCCCAGGTACGAGAACTTCATCGGCGGGGA
ATGGGTTGCCCCGGCGGATGGCCAGTACTTCGAGAACGCCTCTCCGATCGACGGCAAGGTGTTCACCCAGGTTGCCCGCG
GCACCGCGCCGGATATCGAGAAGGCGCTGGACGCGGCGCACGCCGCGGCCGAGGGGTGGGGTAACACCTCGGCCGCTGAA
CGGTCGAACGCCTTGCTGCGGATCGCCGACCGGATGGAACAGCACATCGAGAGGCTCGCGGTCGCCGAAACCTGGGATAA
CGGCAAGCCGATCCGGGAAAGTCTGAACGCCGATATCCCGCTGGCAATCGATCACTTCCGCTACTTCGCCGGTGTGCTCC
GAGCCCAGGAGGGGTCGATCTCCGAGATTGACCACGACACCGTGGCCTATCACTTCCACGAGCCGCTGGGCGTTGTCGGG
CAGATCATCCCGTGGAACTTCCCCCTGTTGATGGCCGTGTGGAAGCTGGCTCCGGCGCTGGCGGCGGGCAACTGTGTGGT
GCTCAAGCCCGCCGAACAGACGCCCGCCTCGATCCTGGTGCTGATGGAGCTGATTGCCGACTTGCTGCCATCCGGAACCG
TGAACGTGGTCAACGGTTTTGGTGTGGAGGCCGGTAAGCCGCTGGCCTCCAGCCCGCGCATCGCCAAGATCGCGTTTACC
GGCGAGACCACCACGGGGCGCCTCATCATGCAGTACGCGACGGAGAACATCATCCCGGTCACGCTGGAACTCGGCGGTAA
GAGCCCCAACATCTTCATGCCCGACGTGATGGCCGCCGACGACGCCTTCCTGGACAAGGCGCTTGAGGGCTTCACCATGT
TCGCGCTCAACCAGGGTGAGGTGTGCACCTGCCCCTCGCGTGCGTTGGTGCACGCATCCATCTACGACGAGTTCATCGCT
CGTGCTATCACGCGCGTGGAGGCGATCGTAGGCGGTGATCCGCTCGACGAAGACACCATGATCGGTGCGCAAGCAAGCAA
TGACCAATATGAAAAGATCTTGTCGTACATCGATATTGGGCGGCAAGAGGGTGCGCAGGTACTGACCGGCGGAGATGCGC
GCAAGGTCGCCGAATACCCCGACGGCGCATACATCCAGCCCACGGTGTTCGCCGGTACCAACAACATGCGCATCTTCCAA
GAGGAGATCTTCGGCCCGGTGCTGTCGGTGGCGAAGTTCGACTCATTGGATGAGGCATTGAAGATCGCCAACGACACCCT
GTATGGCCTCGGCGCCGGGGTGTGGTCGCGCGATATGACCAACGCCTACCGGCTGGGTCGCGGTATCAAGGCCGGGCGGG
TGTGGACCAACTGCTATCACCAGTACCCGGCGCATGCCGCTTTCGGCGGCTACAAGAAGTCGGGCATCGGGCGCGAGAAC
CACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACATCTTGGTGAGCTATTCACCCGATGCCGCGGGCTTCTTCTG
A

Protein sequence :
MAKYAAPGTEGSAVTFAPRYENFIGGEWVAPADGQYFENASPIDGKVFTQVARGTAPDIEKALDAAHAAAEGWGNTSAAE
RSNALLRIADRMEQHIERLAVAETWDNGKPIRESLNADIPLAIDHFRYFAGVLRAQEGSISEIDHDTVAYHFHEPLGVVG
QIIPWNFPLLMAVWKLAPALAAGNCVVLKPAEQTPASILVLMELIADLLPSGTVNVVNGFGVEAGKPLASSPRIAKIAFT
GETTTGRLIMQYATENIIPVTLELGGKSPNIFMPDVMAADDAFLDKALEGFTMFALNQGEVCTCPSRALVHASIYDEFIA
RAITRVEAIVGGDPLDEDTMIGAQASNDQYEKILSYIDIGRQEGAQVLTGGDARKVAEYPDGAYIQPTVFAGTNNMRIFQ
EEIFGPVLSVAKFDSLDEALKIANDTLYGLGAGVWSRDMTNAYRLGRGIKAGRVWTNCYHQYPAHAAFGGYKKSGIGREN
HKMMLDHYQQTKNILVSYSPDAAGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-150 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-158 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-158 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-158 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-158 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-75 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_006520288.1 aldehyde dehydrogenase VFG0082 Protein 6e-151 63