Gene Information

Name : thiC (MYCMA_2333)
Accession : YP_006522068.1
Strain : Mycobacterium abscessus GO 06
Genome accession: NC_018150
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase
Function : -
COG functional category : -
COG ID : -
EC number : 4.1.99.17
Position : 4262372 - 4264012 bp
Length : 1641 bp
Strand : +
Note : -

DNA sequence :
ATGTCGACCCCATCATCCCGTTCCCAGGCCCCGGAAACCGTCACCACGGGTCCGATTCAGGGCAGCGAAAAGATCTACCA
GGAATTGCCCAACGGCCTGCGGGTGCCGCAGCGCCGCGTCAATCTCACCAATGGCGAGTATCTGGACCTGTACGACACCT
CCGGCCCGTACACCGACGCCAACGCAGTCATCGATCTGCACAAGGGCCTGCCACCCCGCGCCGGAATCGTGACCGACCGC
GGCACCCAGTTGCAGCGTGCCCGCGCCGGTGAGATCACCGCCGAGATGGAGTTCATCGCCGTGCGCGAGGGAGTGCCCGC
CGAGTTGGTGCGCACCGAGGTCGCGGCGGGCAGAGCCGTCATTCCCGCCAACCACAAGCACCCGGAGAGCGAGCCGATGA
TCATCGGCAAGGCCTTCGGGGTGAAGATCAATGCCAATATCGGCAACTCAGCCGTCACCTCCTCTATCGCCGAGGAGGTC
GAGAAGATGGTGTGGGCCATCCGCTGGGGTGCCGACAACATCATGGACCTTTCCACCGGGAAAGACATCCACCAGACTCG
CGAGTGGATCCTGCGCAACTCTCCCGTCCCCGTCGGCACCGTGCCGATCTACCAGGCGCTGGAGAAGACCAACGGCGACC
CCGCCGCCCTTACCTGGGAGTTGTACCGCGACACCGTGATCGAGCAGGCCGAGCAAGGCGTGGACTACATGACGGTGCAC
GCCGGTGTGCTGCTGCGGTACGTGCCGCTCACTGCCAAGCGCGTCACCGGCATCGTCTCGCGCGGCGGCTCGATCATGGC
CGCCTGGTGCCTGGCACACCACCGGGAATCATTCCTGTACACCCACTTCGAGGAACTGTGCGAGATCCTGGCGCGCTACG
ACGTGACCTTCTCGCTCGGCGACGGCCTGCGCCCCGGATCCATCGCCGACGCCAACGACGAGGCGCAGTTCGCCGAGCTG
CGCACCCTCGGTGAGCTCACCAAGATCGCGAAATCCCATGGTGTGCAGGTGATGATCGAAGGCCCCGGCCACGTACCGAT
GCACAAGATCGTCGAGAACGTGAAGCTCGAGGAAGAACTCTGCGAAGAGGCCCCGTTCTACACCCTGGGCCCGCTGGCCA
CCGATATCGCTCCTGCGTATGACCACATCACCTCGGCAATCGGCGCGGCCATCATCGCCCAGGCCGGGACCGCGATGCTG
TGCTACGTCACCCCCAAGGAGCACCTGGGCCTGCCGGATCGCAAGGACGTCAAGGACGGTGTGATCGCCTACAAGATCGC
CGCTCACTCCGCCGATCTCGCCAAGGGGCACCCGCGGGCACAGCTCCGCGACAATGCCTTGTCCAAGGCGCGCTTCGAGT
TCCGCTGGGAGGATCAGTTCAATCTCTCGCTGGACCCGGACACCGCTCGCGAATTCCACGACGAGACGCTGCCCGCCGAG
CCGGCCAAGACGGCGCACTTCTGCTCGATGTGCGGCCCCAAGTTCTGCTCGATGCGCATCACCGCCGACATCCGGGAATT
CGCCGCCGAGAACGGCCTGGAGACCCAGGAGGACATCGACGCGATGCTGGCACGCGGCATGGAGGAGAAGTCTGCGGAGT
TCGCCGAACACGGCAACCGGGTCTATCTGCCCATCGCATAG

Protein sequence :
MSTPSSRSQAPETVTTGPIQGSEKIYQELPNGLRVPQRRVNLTNGEYLDLYDTSGPYTDANAVIDLHKGLPPRAGIVTDR
GTQLQRARAGEITAEMEFIAVREGVPAELVRTEVAAGRAVIPANHKHPESEPMIIGKAFGVKINANIGNSAVTSSIAEEV
EKMVWAIRWGADNIMDLSTGKDIHQTREWILRNSPVPVGTVPIYQALEKTNGDPAALTWELYRDTVIEQAEQGVDYMTVH
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFEELCEILARYDVTFSLGDGLRPGSIADANDEAQFAEL
RTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVKLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAML
CYVTPKEHLGLPDRKDVKDGVIAYKIAAHSADLAKGHPRAQLRDNALSKARFEFRWEDQFNLSLDPDTAREFHDETLPAE
PAKTAHFCSMCGPKFCSMRITADIREFAAENGLETQEDIDAMLARGMEEKSAEFAEHGNRVYLPIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-157 68
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-157 68
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 5e-155 66