Gene Information

Name : pyk (MYCMA_1429)
Accession : YP_006521177.1
Strain : Mycobacterium abscessus GO 06
Genome accession: NC_018150
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 2681547 - 2682965 bp
Length : 1419 bp
Strand : -
Note : -

DNA sequence :
GTGACGAGACGCGGAAAGATCGTTTGTACCCTCGGCCCTGCGACCGGTTCGGCCGAGCTTGTGCGTGCGCTCGTCGATGC
CGGTATGGACGTCGCACGGTTGAACTTCAGCCACGGCGAGCATGCCGACCACGAGCAGAACTACCGCTGGGTGCGCAAGG
CATCCGACGATTCCGGGCGGGCGGTGGGCGTGCTCGCCGATCTTCAGGGCCCCAAGATCAGACTGGGCAGATTCGCTACC
GGGTCCGCCCACTGGGCCACCGGCGAACAGGTCCGCATCACCGTTGAGGACGTGGTGGGCACCCCGGACCGGGTTTCCAC
CACGTACAAGCAGTTGGCGGCGGATGCTGCCGTCGGCGACAGACTCCTGGTCGACGACGGAAAGGTCGGCCTGACGGTCG
AAGCGATCGAGGGCGATGACGTCGTCTGCCGGGTGACCGAGGGAGGACCGGTCAGCAACAACAAGGGGTTGTCGCTGCCG
GGCATGAACGTCTCGGTGCCCGCCCTTTCCGAGAAGGACATCGCCGACTTGGAGTTCGCATTGCGGCTCGGCGTCGATCT
CATCGCCCTGTCCTTCGTGCGCTCGCCCAGCGATGTGGAGCTGGTGCACGCCGTCATGGACCGCGTGGGACGCCGCGTGC
CGGTGATCGCCAAGCTGGAGAAGCCGGAGGCCGTCGCCAACCTCGAGGCGATCGTGTTGGCCTTCGACGCGATCATGGTC
GCCCGCGGGGACCTCGGTGTGGAGCTGCCGCTGGAAGATGTGCCCATCGTGCAGAAGCGGGCTATCCAGATCGCTCGGGA
AAACGCGCGCCCGGTCATCGTGGCCACCCAGATGCTCGAGTCGATGATCGAGAATTCGCGGCCGACCCGCGCCGAGGCCT
CCGATGTGGCCAACGCGGTCCTGGATGGTGCCGACGCCGTGATGCTGTCGGGGGAGACCTCGGTGGGCAAGTATCCGCTG
GAGGCGGTGCGGACCATGGCCCGCATCGTGTCCGCGGTGGAGAGCCATTCGGTGAGTGCGCCGCCGTTGACCCACGTTCC
GCGCACCAAACGTGGGGTCATCTCGTACGCGGCACGTGACATCGGGGAGCGCCTCAACGCCAAGGCTCTGGTCGCCTTCA
CGCAGTCCGGCGATACCGTCCGCCGACTGGCCCGGCTGCATACTCCGCTGCCGGTGCTGGCCTTCACCCCGCTGCCGGAG
GTGCGTAGCCAGCTGGCACTCACGTGGGGGACGGAAACCTTCATCGTCCCGGTGATGGAGACCACCGACGGCATGATTCA
ACAGGTGGATACGGCATTGCTGGAGATGGAGCGCTATCAGCGGGGAGATCTCGTGGTGATCGTCGCGGGCGCTCCACCCG
GGACAGTAGGCTCGACCAATCTGATCCACGTGCACCGGATCGGCGAGGACGACCACTAG

Protein sequence :
MTRRGKIVCTLGPATGSAELVRALVDAGMDVARLNFSHGEHADHEQNYRWVRKASDDSGRAVGVLADLQGPKIRLGRFAT
GSAHWATGEQVRITVEDVVGTPDRVSTTYKQLAADAAVGDRLLVDDGKVGLTVEAIEGDDVVCRVTEGGPVSNNKGLSLP
GMNVSVPALSEKDIADLEFALRLGVDLIALSFVRSPSDVELVHAVMDRVGRRVPVIAKLEKPEAVANLEAIVLAFDAIMV
ARGDLGVELPLEDVPIVQKRAIQIARENARPVIVATQMLESMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYPL
EAVRTMARIVSAVESHSVSAPPLTHVPRTKRGVISYAARDIGERLNAKALVAFTQSGDTVRRLARLHTPLPVLAFTPLPE
VRSQLALTWGTETFIVPVMETTDGMIQQVDTALLEMERYQRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-77 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-77 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-77 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-77 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006521177.1 pyruvate kinase VFG0479 Protein 6e-78 41